Questions about ergotamine products and migraine headache

[aspiringchemist]

Are ergotamine products like cafergot etc still used in the US clinically? Does anyone have experiences using these products as prescribed to abort migraine headache?

I know that the various triptan medications have largely replaced ergotamine (if not completely).

This inquiry is regarding the treatment of migraine headache and has nothing to do with obtaining a precursor. Of course I am not seeking medical advice, just knowledge and experience.

 

[Jekyl Anhydride]

It appears to be slim pickins and pricey, but still available.

https://www.drugs.com/answers/cafergot-discontinued-604344.html

https://www.goodrx.com/dihydroergotamine-mesylate

 

[aspiringchemist]

Thanks Jekyl.
Most of the clinical research I've found is 50+ years old. Desperate times have me thinking outside the box. If someone has failed trials with all the triptans available perhaps it's worth trying an ergotamine product.

I personally don't know much about the similarities and differences between triptans and ergotamine products but intend to research as well as speak to the treating neurologist.

 

[fairnymph]

When I worked in retail pharmacy 12yrs ago we occasionally dispensed it.