4mg suboxone to oxy conversion?

[lman_15]

I've been on suboxone maintenance for roughly a year, I started off with a dosage of 24mg, have managed to taper down a significant amount and am currently at 3mg-4mg per day. I'm planning on jumping off the suboxone and switching to oxy, what's a safe dosage to start with? My plan was to take my suboxone early as possible the day before, then the following day wait as long as possible to take my first dose of oxy. Lemme know your thoughts as to:
1) what is a good individual/one use dose ?
2) what would be a realistic daily dose be ?
3) how often will I have to redose over the course of the day to stay well?

Thanks in advance,

lman

 

[Keif' Richards]

Hey Iman! First, I have a few questions for you if you don't mind. I know you're not new to Bluelight and I'm not remotely condescending when I say, please let's try to keep the discussion moving along in an academic, HR-centered fashion. I'm not sure what your purposes are and have no judgement either way, but you're aware of our dislike for "how can I get high/buzz etc." type threads, so please be kind!

Is this for pain management purposes or are you maintaining a habit and merely switching your DOC? This is important on multiple levels, because for those who are unaware, being high, intoxicated, euphorious and experiencing analgesia do not follow linear paths in most individuals. It's a much, much more complicated beast trying to appropriately treat someone's pain vs. trying to prevent them from experiencing withdrawal.

What is your previous experience with Oxycodone? Do you have a benchmark? When you say "realistic", what does this mean; financially, legally, socially? Again, your last question is heavily based upon whether you desire analgesia or euphoria as a primary objective. An individual should be able to maintain with 3 or even 2 dosages of Oxycodone per day, but 3 is going to be the norm, preferably equidistant. Frequency is also heavily dependent upon your sleep schedule. If you can sleep until morning without needing a midnight dose, great.

To provide effective analgesia, you're likely going to need up to 4 individual dosages per day. If analgesia is what you're after truly, then while I and the rest of the fam are happy to help, a pain management specialist will ultimately be more beneficial to you. Anyway, let me know and we will go from there!

The conversion from Buprenorphine to other Opioids and vice versa is not simple or straightforward. Prior to getting back to me, try to educate yourself regarding the basic differences between Agonist/Antagonists and Agonists.

 

[lman_15]

Hey brother thanks for the quick reply, I really appreciate it!

"let's try to keep the discussion moving along in an academic, HR-centered fashion. I'm not sure what your purposes are and have no judgement either way, but you're aware of our dislike for "how can I get high/buzz etc." type threads, so please be kind!"

100% brother, I couldn't agree with you more, this isn't a "how can I get high/buzz" thread this is a "how can I avoid overdosing and dying when switching from subs to oxy after a significant break from hard opiates" thread, my genuine intent is to figure out how I can move from a maintenance dose of suboxone to a functional dose of oxy

"Is this for pain management purposes or are you maintaining a habit and merely switching your DOC"

I'm switching my DOC from subs (dr prescribed) to oxy (street purchased), which I know is inadvisable however, I'm here to help myself not overdose and not die, so please keep the lecturing part regarding how I shouldn't be using opiates, etc, away as they're not helpful, the switch is going to happen either way, it's just a matter of whether I'll have the information necessary to make educated choices around dosage and frequency of use, so no pain management strictly withdrawal management

"What is your previous experience with Oxycodone? Do you have a benchmark? When you say "realistic", what does this mean; financially, legally, socially? Again, your last question is heavily based upon whether you desire analgesia or euphoria as a primary objective. An individual should be able to maintain with 3 or even 2 dosages of Oxycodone per day, but 3 is going to be the norm, preferably equidistant. Frequency is also heavily dependent upon your sleep schedule. If you can sleep until morning without needing a midnight dose, great. "

I'm currently 28 years old, I started using oxy around 14, from 14-16 I'd use as often as once every month and as little as once every three months, mainly taking percs and oxy 10's anywhere from 10-20mg per use, 16-19 as often as once every week to as little as once a month, mainly percs and oxy 10's and oxy 20s dosage anywhere from 20-40mg per use, 19 I did it approximately every week once or twice anywhere from 20-60mg per use, 20-21 did oxy everyday for two years, anywhere from 80mg-240mg a day, during this time I would occasionally use heroin or morphine or methadone to substitute when I couldn't get my DOC. 22 was rehab, 22-24 sobriety, 24-28 relapses, oxy, heroin, fent, then methadone maintenance then relapse, then suboxone maintenance and now I'm here.

I started my suboxone maintenance roughly 1 year ago at 24mg, I'm currently hovering around 3-4mg per day. I'd like to switch to oxy, looking to hold back withdrawals and live as functioning of a life as possible. I'm a small business owner and make a lot of $$$ but I'm very active, I work roughly 60+ hours a week and spend a lot of time walking around, doing appraisals, etc. so I'm not trying to be slumped on a couch catching a nod, I'm trying to be active and get shit done.

Hopefully, I gave you an adequate background on myself, my usage, my history, etc. so you could further inform me, lemme know if you need any more info, also as always thank you for your time!

 

[lman_15]

bumping this ....

 

[lman_15]

4mg of suboxone a day to daily oxy dose conversion?!?!?

 

[opamorph]

4mg buprenorphine is the equivalent of 40mg morphine which is in-turn equivalent to 26.6mg oxycodone or 25mg rounding down.

Assuming 1:1.5 morphine to oxycodone conversion and 1:10 buprenorphine to morphine conversion.

Keeping in mind equivalency ratios are for analgesic efficacy and not for opioid withdrawal suppression. If you feel your current dosage is insufficient to hold back your withdrawals speak to your doctor to increase your dose or consider the addition of another drug (Ex: benzos) to help alleviate your symptoms.

Buprenorphine whilst being a partial agonist (doesnt fully activate the receptor) has a much higher affinity to the MuOR then oxycodone (1.5 to 19.8 ), so it will easily out-compete oxycodone when it come to receptor binding coupled with the fact that its half life (time it stays in the body) is significantly longer. Switching to oxycodone 25mg to manage withdrawals can require multiple daily dosing due to first order elimination and shorter half-life. So you are unlikely to feel any benefit following abrupt cessation of suboxone and commencement of oxycodone.

In short switching from a partial agonist to a street bought complete agonist to manage withdrawals after being in maintenance for one year on your own is not only highly not recommended without input from and the direction of a clinician, it can easily result in a relapse and a risk of further dysfunctioning your life.