Yeah I've always been the disso kind of guy and fell for the thought initially that MXE's warmth would have been due to opioid agonism (which it was not, of course, not primarily **) and so that, maybe, becoming enrolled in the opioid maintenance program might aid with dopa's absolutely unhealthy disso use / craving / habit as neither he wanted to come out with a wrecked bladder, spend more lifetime in prisons than absolutely needed nor was he able to stay clear of these chemicals which infiltrated his mind in a way much similar as might have done heroin to other people... just the ultimative chemical love comfortable happy cuddle party of silky coziness devoid of any fears or inihibitions ...
** now that I think over it again maybe delta opioid / enkephalin has to do with that too ... the only siginificant one here was bromadol and that beast indeed had interesting feelings too.
I had truly alien experiences with dissociating while on morphine. There were rumors that the 3-HO ones were opioids and at least what I can say from sampling 3-HO-PCx that for me there was a significant difference in how it felt overall, with the 3-HO being a lot more like my experiences of while being on morphine maintenance & doing disssos, versus e.g. O-PCM, MXE, K, 3-MEO-PCE etc. and at least I got away with so much more absolutely wreckless disso use health-/personality wise (also a bit of a bold statement over which I should think again, probably) compared to what I've know and saw with people using e.g. opioids so yeah I meant that they are kinda siblings receptor-wise (a handful dextro opioids being dissociatives and the other way round. Also dissos break tolerance against opioids, the maybe most feared one out there after benzos, while being pain killers themselves). And that IMO it's better to leave disso's alone until their pharmacology is truly settled and measured (knowing they have intrinsic opioid activity but yeah, then again they don't and this is part of the weird stuff?).
