harrytroy93
Greenlighter
- Joined
- Apr 20, 2018
- Messages
- 14
does zyprexa block the affects of gabapentin and also does zyprexa block tobacco and coffee im not sure how zyprexa works exactly
Olanzapine is a Dopamine-2 receptor antagonist. This will cause some blunting the ability to feel good/sense of reward from other drugs which stimulate dopamine. This includes cigarettes, but coffee not really. With gabapentin, olanzapine will not block any of the action of gabapentin, at least in terms of medical usage. I suppose it is possible for gabapentin to lead to some dopamine release, but if so, not much.
You are likely taking the olanzapine for something going on in the brain which is characterized by excess dopamine. Usually this medicine is prescribed for psychotic disorders that may include delusions, auditory and visual hallucinations, paranoia, agitation, or excessive activation. It is also a drug which is used effectively for bipolar disorder and the mania which comes with it. Sometimes it can assist with the depressive states of bipolar.
Stopping prescribed olanzapine could be a bad idea for you, depending on what it is treating. Coming off antipsychotic or antimanic class of drugs has the potential to cause you big problems depending on how necessary they are for you.
It is a serotonin 2A receptor antagonist as well, but this action actually helps keep dopamine action happening in other areas of the brain where dopamine is not causing problems. With the medical use of olanzapine, you only want to decrease dopamine in the mesolimbic cortex. The 5HT2A action is what makes this drug an "atypical" or "second generation" antipsychotic by helping restore dopamine activity in the other cortical pathways (not mesolimbic) to help stop down feelings which can be created by a 1st generation antipsychotic (blunting dopamine everywhere vs. blunting dopamine where it's needed).
The 5HT2A antagonist properties will block effects from psychedelic drugs. However, this action helps make the drug not as anti-dopaminergic as previous similar drugs which used to be more commonly used.
i wanna be able to feel the effects of the other medicines im not trying to get high but i want to feel the effects of the medicine euphoria and eveything