Neuroprotection
Bluelighter
- Joined
- Apr 18, 2015
- Messages
- 1,082
Hi all. I know this may sound like a stupid question, but I just want some clarification.
How powerfull are NSAIDs like celecoxib in comparison to opioids like morphine in there ability to reduce pain. I do understand that NSAIDs supress inflammation, and can therefore directly address one of the key causes of some types of pain. However I am more interested in the effects of the two distinct drug classes on general non inflammatory pain. I recently read a study which claimed that in children with serious injuries, pain management using the NSAID ibuprofen was comparable to the prototypical opioid morphine in ethicasy, with far fewer side effects and no tolerance. I am also aware that for long term pain management, opioids may be preferred over NSAIDs which can have extremely dangerous side effects like bleading stomach ulsers and kidney failure. Has anyone had experience of both drug classes? If so how did they compare for blocking pain? I have never taken opioids, but I have tried ibuprofen, it rapidly and completely eliminated a severe headache which had almost caused me to vomit due to the pain.
How powerfull are NSAIDs like celecoxib in comparison to opioids like morphine in there ability to reduce pain. I do understand that NSAIDs supress inflammation, and can therefore directly address one of the key causes of some types of pain. However I am more interested in the effects of the two distinct drug classes on general non inflammatory pain. I recently read a study which claimed that in children with serious injuries, pain management using the NSAID ibuprofen was comparable to the prototypical opioid morphine in ethicasy, with far fewer side effects and no tolerance. I am also aware that for long term pain management, opioids may be preferred over NSAIDs which can have extremely dangerous side effects like bleading stomach ulsers and kidney failure. Has anyone had experience of both drug classes? If so how did they compare for blocking pain? I have never taken opioids, but I have tried ibuprofen, it rapidly and completely eliminated a severe headache which had almost caused me to vomit due to the pain.