There is no basis to this statement at all. Is it advisable? Perhaps not
Is there any evidence at ALL that 3consecutive days of MDMA use is harmful? NONE WHATSOEVER
In fact, in PIHKAL Alexander Shulgin cites a tolerance study where subjects were given 120 mg - 160 mg MDMA daily for 6 days.
You won't get much effect from the mdma on the two following days. You will feel buzzed but not good.
Unfounded Assertion, many people actually DO continue to feel the effects just fine
After the store of serotonin has gone, you don't have any more to release.
Completely False - the synaptic vesicle is constantly being refilled with serotonin -- synthesis of serotonin
never stops it may be reduced but it is still going on
The mdma then metabolizes differently and can cause harm.
Total Bullshit -- how MDMA is metabolized has nothing to do with serotonin release -- the only difference in MDMA metabolism caused by MDMA use is the inhibition of CYP450 enzymes -- causing a longer but not different metabolic process
In the best case you will feel really down after your weekend. In the worst case you might cause nerve damage or any kind of other shit. Not a good idea
Again, total Bullshit
Posts like yours contribute to people
NOT LISTENING TO HARM REDUCTION your are scientifically WRONG, and assert ridiculous things (nerve damage after 3 rolls - lolz lolz)
To the OP --
Based on many thousands of experiences, and outcomes the following is likely:
1. The subjective experience of MDMA --
for most people is reduced on consecutive days of use.
2. It is likely you will experience an altered perception, and perhaps a slightly depressed mood on day 4 -- however a small percentage of persons experience elevated mood as an afterglow for days or even weeks following MDMA use
3. Due to the catecholamine release and cascade as well as the possible inability to sleep -- it is very likely you will be physically exhausted on day four
If the substance you have is not MDMA or MDXX -- you could be subject to harm by taking an unknown substance for 3 consecutive days
the likelihood that you will have a negative experience and/or after effects increases based on the following:
1. concurrent use of alcohol
2. excessive concurrent use of cannabis (research cannabinoids like Spice/K2 should be avoided like the plague)
3. concurrent use of cocaine/ amphetamines/methamphetamines
4. failure to remaine properly hydrated with electrolytes (not dehydrated, not over hydrated on water alone)
5. failure to eat balanced meals
6. use of redosing MDMA or multiple dosing MDMA on any of the 3 consecutive days of use