Life & Death 1 for DOS... great game. You too can learn how to remove someone's appendix. You know, just in case. As I recall you are a GI doc, and you can diagnose gas, bacterial infections, kidney stones, arthritis, appendicitis, & aortic aneurysms (the latter two require surgery). There's different medical imaging tools to help, surgeries can have complications arise which you have to deal with (I still remember - lidocaine for PVC, atropine for bradycardia!), and you even manage your surgical staff, some of which don't get along together.
Or if you feel like it, you can be a maniac - diagnose the first person who you see with appendicitis, and as soon as you enter surgery start slicing them up
sans anesthetique. The head of surgery doesn't like that. Another cool trick is putting someone with a pacemaker in an MRI (needless to say that would make a mess), or someone with shellfish (iodine) allergies in CT with iodinated contrast. Both end up killing the pt and you get a lecture.
(A confession: hemophobia runs on my father's side. I'm a little better than he is, but when I was a teen playing L&D1 - even though it's only 4-color CGA and PC speaker sounds - the first time I went to surgery, draped and anesthetized the poor bastard, incised across the lower right quadrant... saw the bleeders start... and almost passed out in my fucking chair. I got pretty tolerant to it, though, and soon enough I was fixing people's aortas.)
The sequel, "Life & Death 2: The Brain" was even more harrowing. This time you're a neurologist, and you have 256 colors instead of 4. You diagnose migraine headaches, drug addiction, hysterical paralysis, neuropathy, infarcts, and do 3 different brain surgeries - subdural hematoma, brain tumor resection, and aneurysm repair. Even though it's a simulation game, the latter two are about as difficult as you would expect brain surgery to be. As for drug addicts, part of the deal is you get patients who are supposedly addicted to morphine or cocaine - diagnosed when the only abnormality is fucked pupils. You also have a magical clipboard, one option being "prescribe codeine".
Doctor sekio says to his cocaine-addict patient, "you know what you need? some opioids to even the high out." Unfortunately if you go around Rx morphine for everything, the addicts end up dead and your boss gets pissed. You even get a scene of hospital staff eating pizza in the morgue and cracking jokes about your crap surgery ability.
Oh, and this time you can be a maniac by doing things like jabbing pins (used for pain perception testing) into your pt's eye, give them nitroprusside and dopamine and watch their BP go to 0, or (this is a good one) operate on the wrong side of the head...
Definitely part of what made me interested in medicine! I highly reccomend.