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  • Trip Reports Moderator: Cheshire_Kat

(DXM / 60mg daily) -- I took DXM every day for a year. This is my story. (LONG)

MyDoorsAreOpen

Bluelight Crew
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Aug 20, 2003
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I've put off making this thread for a long time. I chalk this up to my natural perfectionism (and thus procrastination) in the face of anything so astounding. Even now as I type this, I'm tortured by the feeling that nothing I write can do the experience justice. My feelings regarding the whole matter are incredibly mixed, owing in no small part, as we shall see, to the profound effect of DXM on a person's emotional responsiveness to the outside world.

In early July of 2011, I was a third year medical student about to begin my required six week surgery rotation. The day my rotation began, I was just back from a very disappointing music festival where there was an invasive security presence and piperazines instead of MDMA. Now I'm not the type to go into any experience with dread -- I really try to start off any new project with a positive attitude and an open mind, including activities I've been warned are hard. That said, here I was sitting with my classmate "S", a wicked piperazine hangover, and a bitchy Puerto Rican lady who was secretary of the surgery department, telling us that since there were only two of us students on this rotation, and a student needed to be on with the residents every day, I would be on call every other night 8o. When I pointed out politely that this was unfair and unreasonable, and no other students other months had been subjected to such a demanding schedule, her response was "Cry me a river." My reserve for taking things in stride was exhausted in one fell swoop.

A few weeks prior, I had read on BL someone posting that he could feel doses of DXM as low as 60mg. I'm a big fan of minimum doses, so I decided to take 60mg of DXM (and toke a bit) and go for a bike ride. I ended up in an elated and motivated mood, my thoughts racing joyously and with surprising detail about how my wife and I might be able to stay in our quaint little town right opposite New York City on the Hudson River for years to come. I arrived home feeling slightly disconnected from my body, but absolutely pumped with the idea, and eager to sell her on it. She thought the idea needed more thought, but it didn't strike her as irrational in any way, and she didn't seem to even suspect I was on any drugs.

My first morning of surgery, on a whim, I decided to once again take 60mg of DXM. By this point I was truly not looking forward to being there, and I hoped it would give me a burst of positivity and motivation. I ended up getting a lot more than I bargained for. On the car ride to the hospital, I began to feel very stimulated and motivated, and ever so slightly dissociated. But I could speak and move with no difficulty. I felt absolutely no fear whatsoever, and don't know that anything could have made me feel fearful.

The surgery residents in charge of us, surprise surprise, turned out to be overworked and unhappy people, who had no motivation to be nice to S and I. The chief resident "D" was a first class asshole, who instantly did not like me, because I wouldn't just submit and do exactly as he said. (Thankfully I knew from the start he had no input into my grade.) I should mention now that I do not suffer assholes well, and never have. This is a combination of being a sensitive individual, and also having a strong ethical principle against hierarchies of domination. If some stiff sends me the message that he's the alpha dog and I should bow down, he's likely to get anything from me but submission. This may someday be the end of me, but it's how I am.

My first day on DXM went very well. I was able to weather the constant barrage of unpleasant interpersonal interactions with complete grace. Much to my happy surprise, I did not feel the familiar lump in my throat, racing vindictive thoughts, bristling skin, or twitchy muscles. I did not lose the ability to look the offenders in the eye or speak to them with calm confidence. Intellectually, I was aware that I was being humiliated. But somehow the message never made it to the emotional centers of my brain. I was able to pretend that I was being addressed politely, and reply as if it were a casual conversation with friends. In retrospect I think this pissed off D even more -- I think a part of him wanted to see me broken and intimidated. I think it vexed him that I did not seem scared to give a wrong answer, and did not fear his scrutiny. Perhaps the purpose of this humiliation was to motivate me into learning and always giving the right answers. But I don't learn that way.

So successful was my first day on 60mg of DXM, that I began to take it every day. I saw no reason not to. It had the added stimulatory effect of reducing my need for sleep and food (which all students and residents on surgery are perpetually deprived of). I would take the DXM right before the half hour drive to the hospital, and arrive at 4AM perky and absolutely pumped to see my patients and write my notes on them, instead of barely awake and grasping at straws for the motivation. I'd be making jokes and smalltalk with the nurses as I wrote my notes, something I never felt like doing before.

It's kind of cliche in a "tastes like chicken" sort of way, to describe any drug's effects thusly, but 60mg DXM reminded me a lot of MDMA. The increased sociability and lack of any social inhibitions, the stimulation and wired feeling, and the boundless motivation were remarkable. Unfortunately, also like MDMA, I found myself gurning, to the point where I ended many days with a headache. The mild dissociation, however, was where the analogy ended. This was at the same time the most interesting but also the weirdest effect of the drug. The dissociation took the form of decreased tactile sensitivity, especially to temperature, but to a smaller degree to proprioception, though never to the point where my coordination suffered. Visually, the world at times would take on a "washed out" look, somewhat like a photonegative, where the contours and hues of objects would take on a funny quality I find hard to put into words. I bet anyone who has used dissociatives at sub-hole doses knows exactly what I'm talking about.

Dealing with my attending physician was a lot easier than dealing with the residents. Though he was a tough teacher, Dr. J was not out to humiliate anyone. My respect for him was genuine. My complete lack of inhibition in piping up and answering his questions while we were on rounds seemed to impress him, and send him the message I was not at all intimidated by him or his trade. Thanks to DXM. I felt genuinely motivated to read and learn what he wanted me to learn, such that when he'd "pimp" me with questions, I'd give the right answers, with calm aplomb. I remember once Dr. J asked a question of all of us, which struck me as a trick question with a ridiculously simple answer. So without a second thought, I just spoke up and gave the simple answer which had first crossed my mind. Dr. J pointed at me, and at first I thought he was going to make a humiliating example out of me. Instead he said, "I like the way this guy thinks. He keeps it simple and doesn't overthink things. And he's absolutely correct." I glowed for the rest of the day. If only Dr. J knew what a problem overthinking things has always been for me!

At the end of the rotation, Dr. J took me into a room for feedback. S had just come out of the room pale as a ghost, and I had heard Dr. J could be rather harsh with his final feedback. I sat down across the table from him, a bit nervous. He said in his lilting Indian accent, "I'll keep this short, MDAO. I am recommending you for highest honors." I was stunned. For a split second, I wondered if it was a joke. It certainly didn't feel like I earned it. If only he knew, I thought to myself, that I couldn't have made nearly so good an impression without DXM.

Still, the results spoke for themselves. I began my fourth year of medical school still taking 60mg of DXM every day, and after my experience on surgery, I saw no reason to stop. Sure enough, I ended up making a strong impression on all of my fourth year rotations, and getting a couple of glowing letters of recommendation. I never felt the slightest twinge of nervousness as I went on day-long interviews for family medicine residencies, and ended up spontaneously telling a number of stories during my interviews that I could tell sincerely impressed and entertained my interviewers, and gave them the impression I was a highly interesting and articulate person with a lot to say. In the end, I ended up getting my number one choice, one of the most renowned and sought-after family residencies in my entire region of the US! And it felt effortless.

Many of my fourth year rotations took place at the same hospital where I'd done a lot of my third year rotations, including surgery. It's an old, highly traditional inner city teaching hospital, with a very hierarchical and high pressure work environment. It's populated with shark-like internal medicine residents, mostly from abroad, whose only professional goal is to score a high-paying medical subspecialty. In my third year days before DXM, I'd found it a highly intimidating place, and was definitely received by people above me as something of a lost puppy who's fun to kick around. Going back there my fourth year, on DXM, felt entirely different. Suddenly I was treated with respect, even friendliness. I chalk this up to carrying myself with more confidence and medical knowledge, and having made it through the gauntlet which is third year of medical school. I'm sure 60mg of DXM every day played no small role in this, though.

DXM changed the way my mind worked. Most detrimentally, I found it harder to write. I found I'd often "get ahead of myself" and write the second letter of a word before I'd written the first letter. My handwriting got worse. I found it hard to hold an entire long sentence in my head, and found myself having to go back and correct a lot of wrong verb tenses and run-on sentences. I no longer felt as eloquent, and no longer had the urge to express myself in complicated purple prose. For the first time in my life, I felt able and satisfied to state things simply, and use no more words than were necessary. This made me realize how much of my former speaking and writing style was borne out of repressed anger and frustration (as it is for many prolific writers, I suspect). With the anger and frustration completely removed, simple, logical ways of stating things just sufficed.

Less detrimentally, but still controversially, I found my emotional state completely disconnected from stimuli in the outer world. I found I could very easily choose not to attach any emotional content to something I was experiencing, doing, or saying, something I've never been good at or even seen the use of. This helped me countless times in plowing through tasks which were sheer drudgery, or discussing other people's great suffering without vicariously feeling any of it. At the other end, I found during my residency interviews that I could muster a warm, genuine looking and even genuine FEELING smile on command, whenever the logical part of my brian told me that the other person was inviting me to laugh or be amused. Again, I think this has gone a long way to convincing my higher-ups and patients that I'm a highly likable person. But inside, I mostly felt emotionally blank. My days had neither joy nor sadness. Only tasks to be done.

All this time, I never experienced anything I'd consider a comedown or a hangover, nor any side effects that nagged me to quit. But then something slowly changed. I began to develop tolerance to the mild dissociative effect. I used to be able to count on the DXM to keep me in a relatively good mood. But more and more, I started having days that were marked by a low level of fear and paranoia. Like the perkiness and motivation I'd experienced before, this fear seemed unprovoked by, and unrelated to, anything in my external world. I began to feel that there was a wide gap between how I was perceived and what was really going in in my head, that I was just playing a role on a stage, and that no one at work knew the real me at all.

The way the DXM made incredibly daring served me well as a medical student and interviewee, but soon posed problems for me as a resident with responsibilities. On a couple of occasions I took the liberty of doing things without supervision or prior permission, and although no patients were ever hurt, I was criticized by my director for being a "cowboy". My wife also became concerned about me taking a psychotropic medication every day, without the supervision of a medical professional. So I stopped taking it every day. I still take it occasionally, at doses a little lower (around 45-50mg) when I'm having a tough day and would rather just glide through it.

Interestingly enough, some of the personality and thought process changes I've gone through over the past year have remained. I remain more sparse and to the point in the way I speak. I feel less moved to post on BL, and when I read my old posts from before my DXM year, I don't recognize myself and find them convoluted and hard to read. I remain better at working with calm, analytical people. I'm more self-confident and outspoken. I'm not as easily ruffled as I once was. I daydream less, and find myself living in the present moment, as opposed to needing some exciting future to look forward to. I'm also a more deeply spiritual person, with fewer lingering doubts in this area. I don't think I will ever be able to separate which of these transformations were a result of the notoriously transformative process of attending medical school, which were the neurohormonal effects of becoming the father of triplets that same year, and which were brain changes enacted by DXM.

I cannot in good conscience recommend anyone do as I did. Mania and psychosis are real risks of long term DXM use, and I definitely experienced a lot of the former and flirted with the latter over the course of the year. That said, I proved right the recent study that suggests that DXM is an excellent antidepressant and anxiolytic. This study noted that people with the gene for the faulty serotonin receptor who are naturally predisposed to depression, lowered pain thresholds, alcoholism, and opiate addiction, are the most likely to get these benefits from DXM. According to 23andme.com where I submitted my DNA for analysis, as well as family and personal history, I am certain I am one of these people. That said, I think more research should be conducted on this compound for its psychoactive properties.

If you've made it this far, thanks for reading. I have much more to say, and I think I'll be adding anecdotes to this thread from over the past year, as they come to me. Any comments are welcome.
 
Wow. Thanks for the report.

I was considering adding dxm polistirex bid to my current regimen to keep tolerence at bay, but cycling on and off as needed.

I think memantine would have been far superior but that's just me.

I'll come back to this because I have a longstanding relationship with this particular chemical and would like to get into more detail about this.

Great report though, very informative and entertaining.

Thou
 
Wow interesting. But I have to ask would you have been able to live with yourself if you made a mistake that had irreversible consequences?
 
Thanks a lot. I am always keen to hear about a truly successful relationship with a psychoactive chemical, wherein someone is able to use a psychotropic drug as an effective tool in furthering their goals, as opposed to someone just having a good time.
 
Although I haven't used any disassociative except MXE, very good read !
 
Out of curiosity, how did you feel like it affected your memory? Any noticeable changes? Also, did you take DXM powder or did you get robotusson pills from the store?
 
Wow interesting. But I have to ask would you have been able to live with yourself if you made a mistake that had irreversible consequences?

No, I wouldn't. This is why I quit.

Emericana said:
Out of curiosity, how did you feel like it affected your memory? Any noticeable changes? Also, did you take DXM powder or did you get robotusson pills from the store?

It had surprisingly little effect on my memory per se. It did at the beginning, however, affect a number of mental processes that are vital components of memory: I found it slightly but noticeably harder to gauge the relative likelihood of competing explanations, which in my trade made the formation of differential diagnoses more challenging. I also developed what psychiatrists call "loosening of associations", where I could see potentially meaningful connections between things that, to most people, had little to do with each other. Again, this hindered sorting out the physical exam findings and lab values that were key to making my diagnoses, versus those that were useful only as supporting evidence, if even that. I don't get these effects anymore when I use this drug, or rather, I'm able to notice them and keep them in check.
 
^ You never answered Emericana's second question, the form of DXM. I was curious as well. Of course if you don't want to say, you don't have to. :)
 
Has the writing improved again after stopping the daily use? - I mean the hand writing and spelling. Interesting that your handwriting was effected but no other forms of fine motor control.

Great read. Thanks.
 
^ You never answered Emericana's second question, the form of DXM. I was curious as well. Of course if you don't want to say, you don't have to. :)

I used the cheapest prep I could find -- the CVS generic brand 8 ounce "Long Acting" cough syrup, with 15mg of DXM per 5cc. The biggest downside was that my bedsheets reeked of fake cherry flavor.

My spelling and writing skills have indeed recovered since ceasing daily use. No, I didn't notice any other real motor deficits.
 
This is very interesting and very similar to how i feel i have changed after abusing MDMA to dangerous levels many years back.

I find I am far less emotional, rarely get angry or aggressive, things don't bother me, i am able to logically deal with life and situation and people and easily logically fake emotions where i feel it will help my goals. I find it very easy now to manipulate people as i am able to see past my emotional bias towards them or situations and thus easily play devils advocate, understand their motivations and emotional weaknesses and interact in a way thats assures i get what i need from them.

I sometimes feel i am acting like a sociopath would except do still have some emotion left, enough to keep me aligned to moral beliefs and never hurt others if it all possible. I'm sure all this has to do with messing with my serotonin levels? In any cause i always feel enlightened somehow due to this "freedom" from emotional weakness. No sure if that makes sense. On the other hand though i can still bawl at sad movies, so this tells me im still human lol
 
I also do feel very low doses of DXM. My 1st ever dose was 90mgs, washed down with some grapefruit juice. After the (REALLY BAD) come-up i was high as a kite for the rest of the evening, in retrospect it felt like i ate some thc.
 
Fascinating. I've heard of ketamine use as an antidepressant, but I've yet to see someone do the same thing with DXM. I also found DXM at 60mg doses to be quite nice in terms of mood lift. As a side note: I thought it would help me through opiate withdrawals once, but it turns out that the negative withdrawal feelings tend to override any kind of mood lift. I thought the mild dissociation would help, but no dice.

Your description of the low-level sense of fear and paranoia was a reminder of the time I used tramadol for antidepressant reasons over the course of a year. I stayed at the same dose for at least three or four months before the mood lift started to fade and was slowly replaced with a dead sort of woe and nothingness crept into my daily thoughts (if I can be dramatic for a moment).

EDIT: Forgot to ask: what was your method of administration? Coughgels? Pure DXM? I can't imagine you would bother drinking icky bittery cough syrup goop daily.
 
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Inspired by this thread, I decided to give 60mg of DXM a whirl yesterday. Given my anxiety issues, I was expecting to enter some nerve wracking situations in class, and I wanted to see if DXM could similarly release me from the clutches of my emotions, as MDAO described here.

I can't say that the results were drastic in any way, barely perceptible really, but I will say that I did have a significantly more relaxed day than I expected to. How much the DXM influenced this, versus how exaggerated my negative expectations might have been, I really don't know. I also feel like my response to positive emotion was intensified - I often found myself with a big Cheshire cat grin, and I felt a bit silly laughing uncontrollably at a number of mildly funny jokes that my friend made. :D

I think in the future I'll try repeating the experiment at 75 or 90 mg, to try and get a better feel for what's really going on.


On a tangentially related note, I microdosed some psilacetin (~2 mg) today, and I feel very relaxed again today, perhaps even moreso than on 60 mg DXM yesterday.
 
After reading here i also thought about taking a wee bit of DXM again, perhaps next week. How long has one to wait between things like MXE and/or Tramadol before ingesting some DXM?
 
TheAppleCore, keep in mind that I weigh 140 pounds, and generally have a naturally low tolerance to most drugs, provided I haven't abused them. What you're describing is fairly well along the lines of my experience -- calm punctuated my moments of almost childlike glee with a big shit-eating grin on my face.

THCified, I'd wait about a week if I were you. I've read a lot of anecdotal reports of strong cross tolerance between NMDARAs, though the receptor affinity profile for DXM is complex, and distinct from those of MXE and tramadol. For example, I attribute the stimulated and motivated effect I felt to DXM's norepinephrine reuptake inhibition, while its antidepressant effects are probably from its serotonergic properties. As for the famous NMDA receptor antagonism, I'm not really sure. Pure NMDARAs like memantine have failed trials for depression, though anecdotally this drug has great results for reducing social inhibition and self-consciousness, which are in and of themselves sources of depression, at least historically for me.
 
I (ab)used DXM for 1 semester in grad school. I was using between 60 and 120 mg at a time, about three times per week. I can relate to a lot of what you described, especially the part about increased confidence and positive mood. I said things that I would be too inhibited to say while sober. I found people smiling at me and lingering to talk with me where they never would before. I knew I was projecting a genuinely warm and friendly persona that's a lot different than who I am without DXM. I got a lot of joy out of mundane things. Listening to music would put me in a trance.

Unfortunately the side effects were too much. Sometimes my hands would slightly quiver. Sometimes I would get this sensation in my abdominal and neck muscles where it felt like they were going to contract but never did. I would get tired faster, and I would break a sweat faster when exercising. I found it more difficult to focus on boring tasks that required concentration. My bowel movements were terrible.

I love DXM at low doses. The lingering effect the next morning after taking it at night was my favorite part. I would like go back to doing it very occasionally, maybe once a month. Unfortunately, even visualizing a red gel-cap sends a chill down my back, and that has been enough to deter me from going back to DXM.
 
TheAppleCore, keep in mind that I weigh 140 pounds, and generally have a naturally low tolerance to most drugs, provided I haven't abused them. What you're describing is fairly well along the lines of my experience -- calm punctuated my moments of almost childlike glee with a big shit-eating grin on my face.

THCified, I'd wait about a week if I were you. I've read a lot of anecdotal reports of strong cross tolerance between NMDARAs, though the receptor affinity profile for DXM is complex, and distinct from those of MXE and tramadol. For example, I attribute the stimulated and motivated effect I felt to DXM's norepinephrine reuptake inhibition, while its antidepressant effects are probably from its serotonergic properties. As for the famous NMDA receptor antagonism, I'm not really sure. Pure NMDARAs like memantine have failed trials for depression, though anecdotally this drug has great results for reducing social inhibition and self-consciousness, which are in and of themselves sources of depression, at least historically for me.

Norepinephrine without dopamine does NOT cause motivation, and the stimulation it causes is uncomfortable, too-much-caffeine like stimulation.
 
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