Strong antibiotic and LSD - possible dangerous interactions?
A friend of mine is taking an antibiotic (generic: metronidazole, brand name: flagyl) that comes with a warning to avoid ergot-alkaloids. This anti-biotic is powerful and you're supposed to avoid alcohol for 12 hours before taking it and 24 to 48 hours after taking it. She experienced some of the mild neurological side-effects of this antibiotic (specifically disorientation and drowsiness).
I assume this means she can't take LSD while on the antibiotic. How long do you think it's necessary to wait before taking LSD? The half life of the antibiotic is roughly 8 hours, and it supposedly stays in the body for 1 to 2 days. Is 2 or 3 days long enough of a waiting period?
As far as I've found, the major problem seems to be that ergot-alkaloids make the antibiotic less effective because it effects metabolism of the antibiotic, but I've been having trouble getting information on the specific interaction between these two drugs...so I just want to make sure I'm not missing anything. I wouldn't want to put my friend at risk for a psychotic break or anything...
Thanks for any help you all can provide!
A friend of mine is taking an antibiotic (generic: metronidazole, brand name: flagyl) that comes with a warning to avoid ergot-alkaloids. This anti-biotic is powerful and you're supposed to avoid alcohol for 12 hours before taking it and 24 to 48 hours after taking it. She experienced some of the mild neurological side-effects of this antibiotic (specifically disorientation and drowsiness).
I assume this means she can't take LSD while on the antibiotic. How long do you think it's necessary to wait before taking LSD? The half life of the antibiotic is roughly 8 hours, and it supposedly stays in the body for 1 to 2 days. Is 2 or 3 days long enough of a waiting period?
As far as I've found, the major problem seems to be that ergot-alkaloids make the antibiotic less effective because it effects metabolism of the antibiotic, but I've been having trouble getting information on the specific interaction between these two drugs...so I just want to make sure I'm not missing anything. I wouldn't want to put my friend at risk for a psychotic break or anything...
Thanks for any help you all can provide!
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