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Tryptamines The Big & Dandy 4-AcO-DET Thread

it can produce intense euphoria simply due to the profundity of its effects (the same way you can get really euphoric when sober because a significant thing just happened)
- Very well said, Xorkoth! That's exactly how I feel and why I like it! :) Tripping on 4-Aco-DET made me completely quit porn ;) and focus on making music and loving my girlfriend, also noticed long lasting anti-depressive aspect after taking it. I hope it doesn't activate too much of 5HT-2B receptor subtypes- my main concern with most psychedelics is pulmonary vasoconstriction (I'm taking Cardimap occasionally to help preventing it), one of the possible reasons of Alexander Shulgin's death...
Have you personally found compounds that produce similar feeling to 4-Aco-DET?
I have yet to try a bigger dose of 4-Aco-DMT - only tried it up to 22mg which wasn't enough for me at all and just gave me uncomfortable "waiting" feeling and some anxiety, gotta go higher as with DMT where you also may get stuck in the middle with half of your ego still retaining memory access and it's functions. But of all I've tried, 4-Aco-DET remotely reminds me of only DMT. Euphoric comedown seems to have to do with personal realization and with how much can you let go of yourself, similar with DMT experiences once again. I wonder if mixing them together would yield synergy?..8)
It feels for me also that with 4-Aco-DET, set and setting are of a big importance, I found it very useful for chanting mantras and playing singing bowls on the come-up. Pre-trip preparation such as mindful meditation and rituals had influenced my last trip greatly!
 
I tried 4-AcO-DET for the first time recently and I was impressed by it. I wasn't expecting much because I had seen plenty of people say that it's not that great, but I was pleasantly surprised. I really like the style of the visuals, music sounded great, and the trip had a very cosmic feel to it. I experienced a powerful euphoric feeling that I don't often experience. It was a feeling of strong excitement, like a butterflies in your stomach kind of feeling that reminded me of being a young child. This experience was a bit reminiscent of my first few times experimenting with mushrooms. The one thing I really dislike about 4-AcO-DET is that it doesn't last long enough.

I hope it doesn't activate too much of 5HT-2B receptor subtypes- my main concern with most psychedelics is pulmonary vasoconstriction (I'm taking Cardimap occasionally to help preventing it), one of the possible reasons of Alexander Shulgin's death...

Shulgin took psychedelic drugs every week for decades and didn't have health problems until he was in his 80's. He lived longer than most people do. If anything that should reassure you that they're safe.
 
a feeling of strong excitement, like a butterflies in your stomach kind of feeling that reminded me of being a young child
- very good description, I felt exactly like that too! :D

The one thing I really dislike about 4-AcO-DET is that it doesn't last long enough
- I was thinking to take it with harmaline next time for a deeper and longer experience. Harmaline tends to prolong my tryptamines and some phenetylamines, and somewhat lessen the duration of lysergamides (weird?..). I was thinking of starting with 120mg of Harmaline and following it in about 20 minutes by 10mg of 4-Aco-DET. I will definitely report back with results here and something tells me it will be interesting!.. Im tempted to add a little mescaline to that mix as well, but for the sake of experiment purity will do without it the first time 8)

As for Shulgin and pulmonary vasoconstriction: I was just really bummed out by his death, love his books and his chemical art, was waiting for another publication... It was right before my birthday too, I was tripping on 2C-B-Fly which is very emotional for me, also knowing that my father died at 59 from a heart attack, it all added to the paranoia about heart diseases so I read a shitload of material on that topic and that, of course, just scared me more... Still being very cautious about it, avoiding some evident heart straining stuff.
But I agree with you on the safety profile of most psychedelics being pretty good compared even to alcohol and nicotine, not to mention hardcore stims and opiates. Moderation is the key with everything imo! ;)
 
Good idea. I have some pure syrian rue extract, but I've only used it with DMT. Combining it with other tryptamines sounds interesting. I've been curious about it for a long time but I haven't done it because I like to keep things simple. If it prolongs 4-AcO-DET, I'll have to try it next time.
 
I'd like to note that combining psychedelics with MAOI is potentially dangerous, especially if taking daily prescriptions. Also I would advise to avoid driving/riding at all costs when adding MAOIs to your stack! I remember when I needed to drive for just couple of miles in the countryside when I was under 2 tabs of acid (Im very used to take 5-6 tabs) preloaded with 150mg Harmaline - peak comes in differently than without MAOI and a lot stronger, I was lucky I made it safe as I was having very wild visuals and feeling very "floaty".
 
I just ate ~10 mg of ethacetin to get a feel of it. It's my first 4-sub =D The taste is horrid! I will have to find something better than water to chase it next time :S
 
I just ate ~10 mg of ethacetin to get a feel of it. It's my first 4-sub =D The taste is horrid! I will have to find something better than water to chase it next time :S

I hope you've enjoyed it! ;)
I really like the empathogenic effects of it and how clean it feels on the body afterwards, including long lasting rejuvenating feeling, it's one of my favorite psychedelics.

Try natural lemonade or grapefruit juice - thats what I usually use for bitter compounds.
 
It actually felt somewhat strong! I was expecting a pretty mild experience but I was surprised I got to a light +3. I got some nausea off it, but I do have nausea on practically any compound, so... Maybe I should administer it rectally? I don't even know.
Now I understand why everyone was talking about that positive mindset in erowid! I was eating fruits and listening to snarky puppy and felt like the happiest man on earth :)
 
Now I understand why everyone was talking about that positive mindset in erowid! I was eating fruits and listening to snarky puppy and felt like the happiest man on earth :)
Nice! :D

To avoid nausea, try taking the stuff on empty stomach and perhaps use strong menthol Halls mints and lemon balm extract if you have it handy and strong ginger tea - all are useful with nausea for me.
 
I find in general that the AcO esters have longer durations and actually lighter, easier to handle effects than their HO counterparts.
 
This one was extremely short lived for me. I was peaking at T+1 and at T+3 I came down quite abruptly. Took 0.5 clonazepam at T+5:30 and slept Ok.
 
I find in general that the AcO esters have longer durations and actually lighter, easier to handle effects than their HO counterparts.

Can you generalize regarding the difference in durations? Like an hour longer for the AcO esters.. or?
 
Not really, I just notice the development seems slower, and the total duration a little longer. The hydroxys seem to reach a peak faster and more intensely. I used to think 4-AcO-DMT was the exception, because I find it faster than mushrooms, but when I tried pure 4-HO-DMT several times, I found it even faster. I also find there to be differences in subjective effects between the -HO and -AcOs, perhaps simply due to kinetics or maybe because the AcOs are also able to cross the BBB, I really don't know. The differences are the most stark between 4-AcO-DMT and 4-HO-DMT, of the ones I've tried, those two are clearly distinct drugs for me. Honestly I haven't eaten any of them very many times except the DMTs, 4-HO-MET and 4-HO-MiPT. I have never tried 4-AcO-MiPT, but I have tried both 4-HO-DET and 4-AcO-DET, and both 4-HO-MET and 4-AcO-MET, and they each seem quite similar but the AcOs are a little more chilled out and lighthearted in general. Probably because they reach the peak slower.

Actually I only tried 4-HO-DiPT a few times a long time ago, and I tried 4-AcO-DiPT a few times more recently, and if my memory serves the AcO was quite different from the HO, but also my reaction to psychedelics has changed a lot over that time so I really can't draw any conclusions.
 
I like 4-Aco-DET a lot (it's one of my favorite tryptamines) and would like to experiment with it more, particularly in combination with phenetylamines and Harmaline. I would like to extend that magical euphoric blissful state I get on it at the 2-3hr mark and make the come down less abrupt. I also very much enjoy the depth it provides for analytical thought.

As a phenetylamine candidates that's available I thought of Mescaline and all it's analogs (AL, MAL, Proscaline), perhaps even 3C-P, maybe 5-APDB or MDA (if available).

Please post if you tried combining it with anything!
 
I once smoked a tiny dose of 4acodet after a 2ct7 peak. A most delightful state resulted, the visuals of the two together was spectacular.

Ive had a few good trips with it, and ethocin...but all in all, not as favored as miprocin and some of the others. It is a very primal and earth shaking substitution...ethocin et al. Thanks Hoffman.
 
Agreed, the 4-substituted DETs produce a very powerful and serious trip. They're not the ones I would take for a good time but I've had a really great trip on 4-AcO-DET, but the first half of it was quite unpleasant in many ways as I really got focused on my mortality and health and the fact that I'm not so young anymore. On the same trip, my friend felt like he was being abducted by aliens while lying on the couch. Very unearthly feeling thing, but also deeply personal, and for me, very little to no euphoria. Kinda the opposite of 4-HO/AcO-MiPT, which I find to be very euphoric, centered, earthy and humorous.
 
I once smoked a tiny dose of 4acodet after a 2ct7 peak. A most delightful state resulted, the visuals of the two together was spectacular.

Yeah... 2CT-7 with 4-Aco-DET sounds pretty awesome, I'd love to combine these two myself! 8)

Agreed, the 4-substituted DETs produce a very powerful and serious trip.....Very unearthly feeling thing, but also deeply personal, and for me, very little to no euphoria. Kinda the opposite of 4-HO/AcO-MiPT, which I find to be very euphoric, centered, earthy and humorous.

Ive had a few good trips with it, and ethocin...but all in all, not as favored as miprocin and some of the others. It is a very primal and earth shaking substitution...ethocin et al. Thanks Hoffman.

Stragely, but miprocin (4-Aco/HO-MiPT) makes me waaay too agitated and adrenergic and the energy it gives me feels a bit alien compared to 4-Aco-DET.

On one occasion on 40mg of miprocin in the wilderness I was deeply contemplating what it is to be a man - it sharpened my animalistic instincts of a hunter to the max, which was fun but I think I was acting a bit like a maniac and was pretty agressive towards everything. :sus:
Miprocin is euphoric and colorful nevertheles but for me it almost always comes with chest pains and extreme stomach bloating, so my choice falls towards -DET's 4th subs! :p:)

Personal chemistry and metabolism is of the most importance when it comes to drugs of all kinds, I guess that's the reason why certain people get addicted to certain substances in general.
 
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