I have been lurking BL for about a decade and a half and FINALLY have something I can contribute to in any reasonable amount. I picked up a gram of Escaline and dissolved it into 200ml of vodka for liquid dosing purposes (the dissolution of which was almost instantaneous) and 250mg of Etizolam just in case the trip needed to be aborted or at the very least as a way to shorten the duration of the psychedelic dead zone after you are pretty much down but can't sleep for another hour or four.
In terms of my experience with other related substances, I have ingested mushrooms many many times, LSD in the area of 20ish times and 2c-i in the area of 10 times. I also partake regularly in any opiate or opiate like thing I can get my hands on but only oral or nasal ROA. I have a good amount of experience with MDMA, Metyhlone, DXM, Ketamine and Marijuana. Hopefully between all of that I can come up with some baseline comparisons!
Two subjects (myself and S) ingested 75mg of Escaline, I'm a male of about 240lbs, S is a male of about 160lbs. S recently went through a breakup and has been stressing a bit about an apartment he rents out to professionals that has suffered damage from the recent crazy weather, he seems to be taking everything well in stride but he had a previous large dose of acid (800mic) that went pretty badly off the rails a couple years ago so I do my best to make sure he is aware of what he might be signing up for. Given the few reports of this chemical indicating a fairly gentle effect on the psyche (and a common thread to most Mescaline reports), he felt confident that he is in a good enough head space.
Our plan for the evening is music for the come up (starting at 2100h), watch the movie Samsara at some point around peak, go outside for a walk if the peak is too much or after the movie if we are not too overstimulated and then crash out doing pretty much whatever we feel like. The first tingles of the come up start about 20 minutes after ingesting and by 2 hours we are pretty much fully feeling it. There is definite bodyload, but it is pretty minimal compared to other psychedelics, mostly slight indigestion, a feeling of not quite knowing what to do with yourself and not being able to find that nice comfortable spot to sit or stand and not feel like you need to readjust constantly.
My best point of comparison for the trip overall is a low to mid dose of 2c-i, similar enhancement of colours, breathing objects and super sparkly reflective surfaces but light on the visuals. To the plus, I always found 2c-i to be super stimmy and I would walk around my apartment in circles to expend the energy, not at all the case for Escaline, it had an almost depersonalizing effect. The euphoria was a true-er euphoria than 2c-i, felt more natural and whole so that was a plus. In terms of depersonalizing, I felt almost like the first small line of Ketamine, kind of pushed out of my body a bit, content to just sit back against a couch and let things happen.
A great use for this drug would be to watch the movies/videos/concerts/etc. that you see sober and think "that would probably be great to watch high" because it really enhances the visuals but leaves them intact (whereas a good dose of acid will render a movie you have seen a huge number of times almost unrecognizable at points). That said, Samsara was pretty awesome, also, despite the inability to really put forward any useful discussion, you stay in a pretty grounded head space. This was helpful for some of the more challenging scenes that might be slightly more traumatic on a strong psychedelic.
(four hours in, two hours of peak, 0100h) We decided to take a walk to the local gas station (probably 20 minutes while sober) and found that a good amount of the two feet of snow that had recently fallen had melted during the day and completely refroze into pretty much road length skating rinks. This made for a highly uncoordinated and rather hilarious hour and a bit walk to the store with plenty of stops to appreciate how awesome ice encrusted snow looked under a street light or to watch a solitary car drive slowly down a wide stretch of road. On a previous acid trip S and I had gone to a gas station to buy smokes and made it half way through the transaction until we both started laughing uncontrollably like maniacs and ended up just throwing money on the counter and running away due to the absurdity of the situation, S noted that this time we held our shit together through the transaction quite commendably.
Around 0500 we started feeling kind of tired and though still feeling generally pretty good, slight discomforts started becoming more apparent so I suggested we take some etizolam and ease out of it a bit. This was also my first time taking etizolam (also liquid dosing) and we took about 2.5mg each by dropper. It hit me like a truck (full of pillows) and within 20 seconds I was grinning like an idiot and feeling JUST fine. The trip back to the couch was sublime and for the first time since dosing I felt like I found a totally perfect position to hole up in to. We listened to music for another hour and a half as it had become even more amazing than earlier and then promptly fell asleep (easiest come down off a psychedelic I have ever had).
My major thoughts - Don't go in expecting anything more than one hit of acid or roughly 2.5g psilocybe at this dosage, it was on the weaker end by far of my psychedelic adventures. It is a hell of a lot easier than either of those, but the lack of challenge also seems to present a bit of a lack of reward (no epiphanies, and if anything, my thinking was more streamlined and subdued than when sober) and no brain shattering awe at my surroundings (though things admittedly looked quite pleasant). I really wish I had the chance to try Mescaline before this so I could compare directly to that (still waiting to find a place to grow my bridgesii). At this dose, totally pleasant and worthwhile use of a night, nice to have absolutely no thoughts that strayed to the dark side, no feelings of too much intensity, super easy psychedelic all around. The euphoria was really solid but it fluxed a bit with discomfort (which never got bad though, so the euphoria won out completely) and I think this substance makes a perfect enhancer to stimuli you already enjoy.
That said, I am looking to take this up step by step to 100, 125 and 150mg. If it is like my experience with 2c-i, the bodyload and side effects are reasonably similar between low and medium-high doses while the visuals and offbeat thought patterns increase significantly. Despite the difference in body weight, S felt pretty similar about his experience in comparison to mine, he is a bit of a hard head for substances though, but I would suggest (given that you are quite confident you have Escaline) skipping the 50mg-60mg zone. I have no real basis to see how this plays out as more people take it, but I feel like it will open up at higher doses and I think we might be looking at the 125-150 range (unfortunately, as that makes it significantly more expensive than when I considered that 50mg might be the magic dose). I really got a feeling like when I take a single hit of acid and think "hey, this is fun, easy, interesting, etc. but I can't wait to take two tabs next time and get 'there'". Also, with these novel chems, it can take a long time to find the sweet spot as many people rightly don't like to be the first to take the risk.
To the mods, this is definitely a trip report, I can move it over there if you would like and maybe write more of a quick summary here. I felt like this might be a good place to start though as there is SO little info about this substance and the great majority of it can be found in this thread. Please advize. Also, if anyone has any specific questions, I'll try to get back to you promptly.
