Euphorogenesis
Bluelighter
- Joined
- Oct 13, 2014
- Messages
- 185
I have noticed that when i was opioid naive i could take 5 or 10mg of oxy to get pleasent effects nothing like a nod though but still pleasent and definetly noticeable. Then later i got into fentanyl and i developed a pretty serious addiction to it i was doing upwards of 10mg a day for a couple of months. At some point i ran out and was forced to detox. I got clean but i noticed i have some sort of lingering tolerance to opioids of any kind. Where i used to get the good feels from a low dose i now need 25mg of oxy to get the same pleasent effects and around 50-75mg to get my nod on and it's been about a year and a half since i kicked my fentanyl habit. Anyone else experience similar lasting effects from an opioid dependency? I am thinking it has something to do with long-term downregulation of mu-opioid receptors. If anyone knows the concrete science behind this i'd be greatly interested to learn.
Thanks guys.
Thanks guys.