TPD, Dex is all mental and psuedo is all physical, ephedrine is mostly physical, with a touch of mental stimulation.
I would guesstimate that Ephedrine is the mirror opposite of Adderall. Ephedrine is probably 85-90% physical stimulation (like l-amp), and 10-15% mental stimulation (like d-amp), while Adderall is 75% mental stimulation (d-amp) and 25% physical (l-amp).
I've used Ephedrine extensively to treat ADD, and I would say 25mg ephedrine feels like it has the mental stimulation of 2.5mg dexedrine
I've never used Adderall, so I make my own d/l mix with 5mg dex and 6.25mg ephedrine, and it works pretty great for minimal symptom control with no tweaking, I would imagine this is what 8-10mg Adderall IR must feel like.
To answer your question, you will definitely gain a tolerance to the peripheral NE effects through caffeine, adderall, ephedrine, pseudo, kratom etc, but the mental stimulation just isn't there in any significant way like there is in D-amp and D-amp containing products (Dex, Adderall, Vyvanse, etc.) So, you will gain a tolerance to PNS NE levels, but not prefrontal cortex DA and NE levels, with ephedrine, so Adderall should still work well with you for controlling ADD.
tl;dr: If you want a fire under your ass, it will mess with your tolerance. If you want stimulated, mental clarity, then you'll be alright.