slimvictor
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A new drug that could provide new treatment for a range of obesity related disorders without a need to hit the gym has been developed by scientists.
Researchers claim to have created the pill, which they claim provides all the same benefits of exercising without the exertion.
They claim that a hormone naturally found in muscle cells that triggers the calorie-burning benefits of exercise, may have potential as an obesity-fighting drug.
The newly identified hormone, called irisin, increases in the body during exercise, boosting energy expenditure and controlling blood glucose levels.
Medical experts from Harvard Medical School said the new hormone could lead to treatments for obesity, diabetes and even cancer as well as other disorders in which exercise may benefit weaker patients.
But doctors warned that the pill should not be used to replace exercising.
The chemical, named after the Greek messenger goddess Iris, also helps to produce 'healthy' brown fat that burns off weight but largely disappears as we age. It is replaced by "bad" white fat which typically sits around a person's waist.
Prof Bruce Spiegelman, who led the study, believes harnessing irisin will lead to better therapies for any illness that can be combated by exercise.
Prof Spiegelman said: "There has been a feeling in the field that exercise 'talks to' various tissues in the body. But the question has been, how?"
"Whether longer treatments with irisin and/or higher doses would cause more weight loss remains to be determined.
"The worldwide, explosive increase in obesity and diabetes renders attractive the therapeutic potential of irisin in these and related disorders."
He added: "Another potentially important aspect of this work relates to other beneficial effects of exercise, especially in some diseases for which no effective treatments exist.
"The clinical data linking exercise with health benefits in many other diseases suggests that irisin could also have significant effects in these disorders."
The breakthrough is an important first step in understanding the biological mechanisms that translate physical exercise into beneficial changes throughout the body, both in healthy people and in preventing or treating disease.
cont at
http://www.telegraph.co.uk/health/h...t-helps-you-to-stay-fit-without-exercise.html
Researchers claim to have created the pill, which they claim provides all the same benefits of exercising without the exertion.
They claim that a hormone naturally found in muscle cells that triggers the calorie-burning benefits of exercise, may have potential as an obesity-fighting drug.
The newly identified hormone, called irisin, increases in the body during exercise, boosting energy expenditure and controlling blood glucose levels.
Medical experts from Harvard Medical School said the new hormone could lead to treatments for obesity, diabetes and even cancer as well as other disorders in which exercise may benefit weaker patients.
But doctors warned that the pill should not be used to replace exercising.
The chemical, named after the Greek messenger goddess Iris, also helps to produce 'healthy' brown fat that burns off weight but largely disappears as we age. It is replaced by "bad" white fat which typically sits around a person's waist.
Prof Bruce Spiegelman, who led the study, believes harnessing irisin will lead to better therapies for any illness that can be combated by exercise.
Prof Spiegelman said: "There has been a feeling in the field that exercise 'talks to' various tissues in the body. But the question has been, how?"
"Whether longer treatments with irisin and/or higher doses would cause more weight loss remains to be determined.
"The worldwide, explosive increase in obesity and diabetes renders attractive the therapeutic potential of irisin in these and related disorders."
He added: "Another potentially important aspect of this work relates to other beneficial effects of exercise, especially in some diseases for which no effective treatments exist.
"The clinical data linking exercise with health benefits in many other diseases suggests that irisin could also have significant effects in these disorders."
The breakthrough is an important first step in understanding the biological mechanisms that translate physical exercise into beneficial changes throughout the body, both in healthy people and in preventing or treating disease.
cont at
http://www.telegraph.co.uk/health/h...t-helps-you-to-stay-fit-without-exercise.html
