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Replacements for MDxx - The Cathinones

MrIbis

Bluelighter
Joined
Feb 23, 2009
Messages
1,950
Hey all, in light of all the recent activity surrounding quasi legal mdxx replacement drugs - i wanted a thread where in we could discuss what you'd prefer to be taking - considering pills are becoming more and more dangerous with the 'what the fuck is in this thing' factor.

My two picks, evidentally, would be;

Methylone (M1, bk-mdma, 3,4-methylenedioxymethcathinone); From wiki
Effects

Reported dosages in clinical essays range from 150 to 200 mg orally and from 50-150 mg intravenously. The most remarkable effects are:

Endocrine:

* hyponatremia

Eye:

* mydriasis

Psychological:

* euphoria
* strong sense of empathy and bonding
* serotonin deficiency
* depersonalization

Skin:

* sweaty palms
* heavy sweating

Miscellaneous:

* restlessness
* chattering teeth
* gurning

Most of these effects are similar to other psychostimulants.

[edit] Resemblance to MDMA
Main article: Effects of MDMA on the human body
Structural similarities between some amphetamine-like stimulants and their 3,4-methylenedioxy- derivatives.
Left: amphetamine, methamphetamine and methcathinone.
Right: MDA, MDMA, and MDMC.

MDMC resembles MDMA in its behavioural profile, as MDMC substitutes for MDMA in rats trained to discriminate MDMA from saline. MDMC does not substitute for amphetamine or for the hallucinogenic DOM in animals trained to discriminate between these drugs and saline.[3] Further, also in common with MDMA, MDMC acts on monoaminergic systems. In vitro, MDMC has one third the potency of MDMA at inhibiting platelet serotonin accumulation and about the same in its inhibiting effects on the dopamine and noradrenaline transporters.[4][5][1]

Mephedrone (C4, 4mmc, 4-methylmethcathinone), for this quote, it's taken from a pretty interesting little trip report from erowid - its quite long:
Substance details

Common/street name: Mephedrone
Chemical name: 2-Methylamino-1-p-tolylpropan-1-one HCL/4-Methylmethcathinone
Physical state: Whitish/Light yellow powder, somewhat 'bally' in composition, although breaks down to a fine powder
Odour: Strong chemical smell, was apparent even through the packaging. Reminiscent of stale urine, with an undertone of liquorice. Not pleasant.
Chemical stability: Stable at room temperatures, in closed containers under normal storage conditions.
Molecular formula: C11H16NOC1
Molecular weight: 213.71
Dosage: Has been reported similar to MDMA, from around 50-200mg, but as it's a Research Chemical, there is no known safe dose. Start small.
Dangers: Toxicity in unknown. Powder is said to irritate eyes and lungs if introduced to those areas and ingestion may cause irritation to digestive tract. Dangers of chronic use is not yet known.
Duration: somewhat shorter than MDMA.

So the experiment begins:

15.30 -- Sitting alone watching TV. 50mg is carefully measured, crushed to a fine powder, and half (25mg) insufflated. Slight stinging in nose and smell is unpleasant, although not unbearable.
15.35 -- A slight uplift in mood, perhaps the beginning of a feeling of being 'wired', rate of heart elevated. Strong smelling and tasting drip down the back of throat.
15.40 -- Another 25mg is snorted. Stinging is more pronounced this time, and with definite feelings of coming up, almost like MDMA but with less push, with soft euphoria. Watching TV is entertaining but not as nice as staring out the window.
15.48 -- Elevation of heartbeat is more pronounced now, and hands are slightly shaky, not unpleasantly so though. Soft euphoria seems to be growing somewhat along with a feeling of content. Feel totally alert and would be able to converse normally with parents at this stage if needs be.
15.54 -- Drip tastes absolutely horrible! I think that next time I try this compound, I'll try an oral dose to bypass this nasty taste.

15.57 --A friend phones me up and we have a half hour conversation, talking flowed easily and although I feel slightly intoxicated it doesn't show in my voice or conversation.
16.30 -- A 100mg is measured carefully, crushed and insufflated. Immediate effects are apparent, a clear headiness and slight 'speedy' feeling. Nose hurts and smell is not pleasant.
16.35 -- A rushing feeling and clear euphoria is felt, but not as pushed as MDMA, feels much softer and relaxed. Heartbeat is up and hands and feet become slightly clammy. Perhaps a slight pupil dilation but unsure, my extremities tingle slightly. This is a good amount to snort I think.
I put on some music -- Nagual Sound Experiment, the album 'Invisible Movements', it's a merge of dub/2-step/grime with influences of drum and bass and a hint of psy. Perfect for this experience I think.

16.42 -- Music appreciation is amazing, the sounds seem to resonate with a clarity and meaningfulness that I get with MDMA. I feel great even due to the fact that hands are slightly clammy and shaky and I'm sweating slightly (although I don't particularly feel my body temperature has risen that much). Cant stop moving to the music and have lost all interest in the TV now, my brain is just going too fast. I feel like snorting more, but the stinging hasn't stopped yet and feel I should wait longer. I've read peoples reports about how when snorting this substance, it becomes rather moorish -- I can see what they mean. The drip still tastes awful.

17.11 -- Pupil dilation and slight jaw movement when talking, not as pronounced as jaw tension experienced with MDMA but almost like when on good cocaine. Just got back from helping my mum and dad load up the car with stuff for a charity event -- talking and acting normal wasn't even an issue and didn't have to hide my intoxication, although it did feel a bit uncomfortable all the same. Decide to measure another 100mg for insufflation.

17.15 -- It feels as though I was peaking whilst helping out my parents. I believe when snorted, it has a quick onset but with effects wearing off just as quick.
17.17 -- Another 100mg in snorted, with immediate effects. This feels good, I'm sped up and clear headed with the same soft euphoria and a small amount of rushing. Perhaps I wasn't peaking whilst loading the car and the latest line has just topped me up.
Music still sounds great although there's little visual effects apart from maybe a slight fuzziness when reading. The drip is even worse this time, having to constantly sip water to help. This feels just like coming up on MDMA, but with less jitteryness (I find that when consuming the first large dose of MDMA of the night, I experience a nervousness at around the 15-45min mark, and this is not apparent with Mephedrone).

17.23 -- The euphoria is growing, along with the jaw tension. Nose stings less. Can't stop bobbing to the now immensely pleasurable music.
17.24 -- Dad knocks on my door and lets me know he's popping out. I find it hard to conceal my intoxication and feel nervous, wishing him to leave quickly. I'm sure he's noticed my large pupils and unconcealed movement of my jaw but don't think he'll mention anything at a later date. D'oh!
17.29 -- I can't believe this stuff is legal. Can't hide my doped smile.
17.40 -- Listening to music and closing my eyes is very satisfying, and even with no CEV it still feels great. I just ground my teeth and they squeaked, not nice! My vision seems to be fuzzing a little more and have a slight sensitivity to light. Feels like I'm peaking on my last line, or the effects seem to be levelling out a little. On this note, I decide to consume a little ketamine, to see what dimension it adds to this kind of compound.

17.48 -- Upon standing, to fetch my ketamine, I had a sudden head rush and fully realised how stimulated I feel, yet with a totally relaxed feeling at the same time. I know you may be thinking it seems impossible to feel both stimulated and relaxed at the same time but this is how I'm feeling.
17.52 -- A small amount (around 30mg) of Ketamine HCL is snorted in the same nostril as the Mephedrone. For me, this amount is on the small side as I use ketamine frequently and have a tolerance, but decided to act with caution, as one should, when mixing RCs with other drugs. The interactions of RCs with other recreational drugs aren't well documented, therefore I recommend if you decide to mix, proceed with caution. Start small.
17.58 -- The effects of the ketamine, even at such a small dose, has started to have an effect. This combo feels good. It brings the emotional depth to Mephedrone, which I found was missing. Music still sounds amazing, but now with the added K dimension, when laying back and closing eyes there seems to be added visual effects, slight patterning and organic forms - nothing geometric though. I think the bump of K increased the movement of my jaw little.

18.06 -- Intense relaxation, think the effects of the Mephedrone is waning a little, although still feel nice.
18.17 -- Effects defiantly diminishing now, the comedown doesn't feel bad though, just a little 'spacey'. Perhaps the downing effects of the small amount of ketamine had an adverse effect to the stimulating properties of the compound.
18.31 -- Friends phoned, and although I felt a little 'wired' whilst talking, conversation was fine and managed to chat for a while. The comedown is less harsh than MDMA but much quicker. Head feels light and airy, jaw occasionally is tense, eyes are less dilated and the smell of the powder in my nose is all but gone. Music still sounds great.
19.15 -- Total baseline, with residual fuzzy effects in my vision. What's suddenly become apparent to me, is the anorexic effects of this drug, because as soon as its effects wore off I became immediately hungry (I have not eaten since my late breakfast). Becoming hungry straight after the effects of MDMA would not happen with me. Even in the comedown I still felt clearheaded and alert, unlike its cousin MDMA.

In conclusion:
Its effects in me were similar to MDMA, clearer with less push, not as empathetic and shorter in duration, stimulating but at the same time with a sense of relaxation. I think this is an interesting new friend, but one which should obviously be treated with respect due to not a lot of information being know about its toxicity, OD dosages and damage of long term usage. Its pleasant effects and short duration when snorted make it a candidate high up on the scale for regular abuse -- something, which due to its short history of use in human beings, can make it extremely dangerous. Always remember when trying a new drug, that there can no way be what is called 'a safe dose'. Individuals do respond differently to psychoactives so caution should be taken, upping the smallest dose gradually. Do your research, tread carefully and have fun.

Personal Comments:
Possibly some kind of synergy of the two would be awesome

Others may argue that ... piperazines could be a decent replacement - but i think as a punter, id much rather be copping these substances as opposed to DMAA and Pips.

Anyway, this is open for discussion, post your thoughts - i'd have compiled alot of data myself - but i dont have the time.

Enjoy
 
I'd be wary of combining the two, simply because the toxic effects of either have barely been explored, who knows what it could result in if people start taking the two combined on a regular basis.
 
I'm all for the discussion, but I'm not so sure I'd prefer to be taking either of those two (relatively unknown and potentially toxic) substances in place of dangerous 'what the fuck is in this thing' pills.

Until more is known, then they're all equally as dangerous in my opinion.

Having said that, I've only done mephedrone and I like it a lot. As has been reported a million times, the problem when snorting it is that it's massively moreish and so I've had to take deliberate steps to make sure I don't rail too much in one setting. I'm also checking myself so that I'm not doing it every weekend. I think it's a great high.

I've not encountered the other negatives though (heart/circulation problems). I've found the comedown has got worse each time I've used it, even on the same doses. A friend of mine who was using regularly at the beginning of the year has now stopped it totally because the comedowns were making her sick - vomiting, nausea etc. within 3-4 hours of last dose.
 
So your asking what is your replacement for MDxx... 4mmc seems to do it nicely, however, I think for punters that want a euphoric high, which is why one would take mdxx in the first place. Should consider just hunting around harder, and saving there money, and buy up when decent mdxx pills come around that you have tested, trialed and enjoyed.

At least when you know you have a rather clean feeling, clean tested mdxx compound, the risks for mdxx are known.

As a replacement though, I can only comment on 4mmc, and from my own personal experience, is that the duration and the unknown side effects make me caution of going out on it. On home chilling with friends it is great but not for an extended night club visit.
 
I have never sampled these substances. Got some 4mmc that I am waiting for a good oppurtunity to take, I do have high hopes for these substances though and if they are as good as I have been lead to believe would rather get them than buying pills that are probably shit.
 
Well Methylone substitutes almost perfectally for MDMA in my own opinion - at around the 300mg dosage mark it easily shits all over any pill in the last 4 years. even in duration of action.

My point in this thread is that people are using these drugs as replacements for mdma given the lack of decent pills about - my questions are, how much are people using, how are they using it (insufflation, orally, iv, plugging it) etc.
 
^The 4-mmc thread answers your question in that regard (at least for 4-mcc). Quite a few anecdotes about method of ingestion, doses, re-dosing etc.
 
^The main one here would be bout M1 and synergies.. 4mmc has been explored alot - but im not yet to meet alot of people with much to say about M1.

I personally love the stuff - it was the cleanest MDMA-type rush i've ever had.. dancing to fucking top 40 music and lovin it..
 
^I'd go bonkers listening to top 40 sober, let alone high. But fair enough hehe.

Only had 2 m1 experiences, both around the 200mg range. The first time was in a club and was awesome, very much like MDMA except it petered off around the 2.5 hour mark. Very chatty. Dancing was fun as. The next time was at a house party and I found that time to be somewhat insular. Still euphoric and pleasant but I just wanted to lay down by myself and zone out, hard to engage in conversation.

I've heard m1 and MDMA have good synergy. I've also heard adding 2cb to that mix is heavenly.

I'm definitely looking forward to trying m1 again, will probably up the dose to around 300 next time though.
 
There's a rumor that a product called 'Bubble' contains M1 and 4-MMC. Anyone heard anything?
 
It could be? It's actually it's advertised as 'Bubbles' and the main site selling it also has a tab link to LU products.

...update: I just received a PM indicating these do contain M1 and 4-MMC.
 
The buble luv contains 4mmc.

How would u guys compare M1 to 4mmc? To me 4mmc feels like a clean pill with a cokey feeling.
 
Yet to come across any M1, doesn't seem as popular as Drone, would deff give it a shot though.
 
The buble luv contains 4mmc.

How would u guys compare M1 to 4mmc? To me 4mmc feels like a clean pill with a cokey feeling.

4nmc for me is a bit more sensual, wind across skin/sun feels nice. Its sort of like a rush with a sharper edge, but not that energetic. If that makes sense. m1 is a bit more empathetic, seems easier to dance on. Only got 2 m1 experiences to compare to like 5-6 4mmc though.
 
I'd love to try combining the two, but I'd be wary of any compounded toxicity similar to what occurs when you combine methamphetamine and MDMA.
 
I'd love to try combining the two, but I'd be wary of any compounded toxicity similar to what occurs when you combine methamphetamine and MDMA.

I prefer a bit of speed in my pills thank u very much! lol Is it that toxic?
 
Meth and MDMA is pretty bad for the olde brain.

But I do like the combination.. probably too much.

I found 4MMC to be quite energetic compared to MDMA.
Would be even more keen on M1 if it is more energetic.
 
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