Well, looks like I'm resurrecting this thread, but for good reason...
I have seen a SERIOUS case of partially Parkinsonian, partially Tourette's -like tics and tremors arise in a dear friend of mine who was using MDPV daily in varying dosages (need to ask him more but he's going through some relationshit right now and the MDPV hasn't helped)... this appeared to last several days, and he now seems to be experiencing EXTREME anhedonia on a level which he has never before encountered. I should mention that he is a methamphetamine VETERAN and I have gone on week-long binges with him and, well, that's nothing compared to him after two days on LOW doses of the stuff, let alone what I'm seeing now...
He says it's the first time he's EVER felt like he's "Jonesing," and we're the sorta people that do smack once every three months because it's an enjoyable experience.
NEVER seen anyone redose so often and so detrimentally, KNOWING that it's fucking them up. Christ, he looks like he's been on Substance D.... and of course, MDPV was developed as a rehabilitation agent for stimulant abusers right?
This may only occur in a minority, but by definition 40% of users is a minority, and even if it is only at the alpha level of statistical significance (5%), then HOLY SHIT FOLKS, let's hope nobody starts putting MDPV in 'pingers' or there will be kids in Melbourne (ever rode a melby tram on a Friday night?) and for that matter ANYWHERE that will simply NEVER stop dropping them... "Wow, these pills are sure WAAAAAAAAY better than any others, I'll have three..."
Seems like a decent CHEMICAL WEAPON to me... that would slip under the radar and not show up in ANY reagent test AFAIK. Further development of higher mass potency, stronger receptor affinity dopaminergic reuptake inhibitors could literally mean that there will be a certain number of people who will be unable to help themselves from pushing the button until their stash runs out - or in this case, in a moment of sanity, was given away "before he had the chance to redose on the shit."
Don't mean to be an alarmist, just trying to keep our dicks and our pussies from getting covered in shit.