Ummm yeah.....
Ok I am sure this has been covered pretty well. Wellbutrin is a weird drug, It is NOT an SSRI and does NOT effect seratonin levels (as if we could really measure them well) all that much via uptake blockade or MAO inhibition. It primarily acts to increase NE and DA levels. It does this in a novel way, that they don't understand really yet. (http://www.mentalhealth.com/drug/p30-b04.html#Head_2)
It has less of an impact on E than SSRI’s do. But according to some, decreases the effects of MDMA. Wellbutrin can increase the chance of a seizure as can MDMA. So this is something to consider if you have ever had one, or ever will. Short term Wellbutrin doesn’t seem to cause too many problems in combination with E. Coke, or Weed. Although I have read scattered reports about wellbutrin and THC causing psychotic episodes. ( which weed can do on it’s own on occasion ). You will probably have to find out for your self how the combination of these drugs works for you. They don’t do a lot of studies on this stuff unfortunately as there is little government funding for projects related to the use of illegal drugs.
[This message has been edited by Dr. Quack (edited 22 October 2001).]