mr mashed
Bluelighter
i was told zoloft was better than prozac for mdma neuro protection if taken half hour before. if anyone educated knows anything about this please help, your knowledge would be very grateful.
-
-
AADD Moderators: andyturbo
zoloft
- Thread starter mr mashed
- Start date
mr mashed
Bluelighter
how would taking beforhand lead to damage? i was under the impression that it would only lesson the affects of pill, via blockage of reuptake transporters. please explain.
"zoloft is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on noradrenaline and dopamine reuptake" (invitro studies on animals. APP guide 2000)
it will decrease the effects of the mdma if taken before
[This message has been edited by SirLSD (edited 15 May 2001).]
it will decrease the effects of the mdma if taken before
[This message has been edited by SirLSD (edited 15 May 2001).]
mr mashed
Bluelighter
many thanx. so if im going to take an ssri to reduce neurotoxidity am i better off taking prozac afterwards rather than zoloft afterwards? has anyone tried zoloft or prozac? or should i stick with my 5htp?
Ive read that it almost completely stops any brain damage from occuring after you've taken ecstasy, if you take it 2 or more hours after the complete effects of the ecstasy have worn off.
I am certainly not a authority on the matter though, I think its something BigTrancer of Entropope could answer. I will have a look tho.
I am certainly not a authority on the matter though, I think its something BigTrancer of Entropope could answer. I will have a look tho.
BigTrancer
Bluelight Crew
- Joined
- Mar 12, 2000
- Messages
- 7,342
SSRI's taken as a post-load (whether they be Prozac, Zoloft, or 5-HTP) have been reported to assist the reduction of neurotoxicity.
That's why it's a good idea to try to have something like one of these substances as a post-load supplement. 5-HTP is probably the easiest to obtain as it's not a prescription only substance. According to many of the pre- and post-loading schemes listed in our FAQ, Prozac and Zoloft are also excellent for post loading.
Note 1: If you are ON a course of Prozac or Zoloft, you'll know that these drugs take a few days to begin working fully in an anti-depressant capacity, and again a further 2 weeks or more to completely clear your system once you've stopped taking them. That means, you can't just stop your course and take MDMA, because chances are the action of the anti-depressant will completely negate any MDMA effect.
Note 2: Avoid combining 5-HTP and anti-depressants (as this combination can potentially cause seratonin syndrome).
BigTrancer
------------------
Load universe into cannon. Aim at brain. Shoot.
That's why it's a good idea to try to have something like one of these substances as a post-load supplement. 5-HTP is probably the easiest to obtain as it's not a prescription only substance. According to many of the pre- and post-loading schemes listed in our FAQ, Prozac and Zoloft are also excellent for post loading.
Note 1: If you are ON a course of Prozac or Zoloft, you'll know that these drugs take a few days to begin working fully in an anti-depressant capacity, and again a further 2 weeks or more to completely clear your system once you've stopped taking them. That means, you can't just stop your course and take MDMA, because chances are the action of the anti-depressant will completely negate any MDMA effect.
Note 2: Avoid combining 5-HTP and anti-depressants (as this combination can potentially cause seratonin syndrome).
BigTrancer
------------------
Load universe into cannon. Aim at brain. Shoot.
Mr E. Moore
Bluelighter
Horse: remember, those prozac tests were conducted on mice (I beleive), we're simply extrapolating that to humans, a big leap to make. I don't beleive similar tests have ever been conducted on humans.
We've also made the assumption (which is a pretty safe assumption) that 5-htp helps to lessen the neurotoxicity. Again I don't think scientific tests have ever been conducted on humans to prove this theory.
Not to say that I don't think that our assumptions are true, just being pedantic really hehe
We've also made the assumption (which is a pretty safe assumption) that 5-htp helps to lessen the neurotoxicity. Again I don't think scientific tests have ever been conducted on humans to prove this theory.
Not to say that I don't think that our assumptions are true, just being pedantic really hehe
element~ed
Bluelighter
could some1 please tell me a good dosage of zoloft as a postload?
thanks
thanks
No more than 50mg.
Although, I don't recommend people taking anti-depressants for post/pre loading purposes.
They do help in releasing seratonin, but its not real seratonin, as the only seratonin that is real is that which is naturally produced from your neurons by absolute or spontaneous release; bananas, greens and soy.
Anti-d’s make you feel ill in the stomach, sore head and DON’T work unless you take them every day for at least a few weeks.
If you pop one after a roll it won’t do much at all except maybe make you feel sick.
Stick with 5htp!
Although, I don't recommend people taking anti-depressants for post/pre loading purposes.
They do help in releasing seratonin, but its not real seratonin, as the only seratonin that is real is that which is naturally produced from your neurons by absolute or spontaneous release; bananas, greens and soy.
Anti-d’s make you feel ill in the stomach, sore head and DON’T work unless you take them every day for at least a few weeks.
If you pop one after a roll it won’t do much at all except maybe make you feel sick.
Stick with 5htp!
BigTrancer
Bluelight Crew
- Joined
- Mar 12, 2000
- Messages
- 7,342
Melting: What's the difference between the two "types" of seratonin you mention (ie. so called "real" seratonin from food, and any other kind of seratonin found in the body)?
You wrote:
BigTrancer
------------------
Load universe into cannon. Aim at brain. Shoot.
You wrote:
As I understand it, anti-depressants do not actually help your body produce seratonin, but rather slow the reuptake of this neurotransmitter. What then is the difference between the action of 5-HTP and an SSRI anti-depressant?
BigTrancer
------------------
Load universe into cannon. Aim at brain. Shoot.
mr mashed
Bluelighter
thanx again for your help rollers but(dont mean to sound ungreatful), Melting i was under the impression that ssri's only block re-uptake not release serotonin, Big Trancer believes the same, but i do know that some ssri's can take up to a month to work. a doctor told me i would have to take Prozac everyday for a week after roll to completely eliminate damage. I have zoloft and hoped it worked quicker than prozac but waiting on more info before i try. i realy want you peoples to know what you are talking about before you reply. i have asked dancesafe for info aswell still waiting for reply will keep you posted.
thanx so much again,play safe.
thanx so much again,play safe.
thats correct bigtrancer. melting is wrong. and you wont need to keep taking the ssri's for a week postload. one dose should do. but yes you do need to take a it for a week or two to induce full antidepressant effects when used as antidepressants.
dingleberries
Bluelighter
sorry, this might be a bit off the topic, but could anyone recommend a good recreational dosage for prozac/zoloft? (not pre/post loading)
and a brief rundown of the effects?
and a brief rundown of the effects?
Duotone
Bluelighter
Some efects of ssri's: postural hypotension, sweating, dry mouth, nausea, headaches, dizziness, drowsiness, constipation, loss of appetite, nervousness, and sexual disfunction. It doesn't sound like much fun because ssri's have no recreational value. Surely you can't be that desperate to get high.
------------------
Everything in moderation including moderation.
------------------
Everything in moderation including moderation.
mr mashed
Bluelighter
thanx heaps everyone, i will give zoloft a go next drop. unfortunetly im in the middle of a 6 month break(head really really needs it) and will have to wait.
thanx again,
not so mr mashed.
thanx again,
not so mr mashed.