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Stimulants Would stimulants worsen opioid withdrawal?

ChemicallyEnhanced

ChemicallyEnhanced

Bluelighter
Joined
Apr 29, 2018
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I have only Gabapentin and Caffeine and (also with Caffeine potentiating Gabapentin), I thought some Caffeine would make me less depressed and bored, but would it worsen things like shaking and anxiety? Even if I take it with a lot of Gabapentin?
 
I normally take my gabapentins (the morning dose) with breakfast with coffee. If you get jittery from coffee gabapentin won't really help with that, but it's not making it worse either.

If you're taking more than the prescribed amount (or if you're been prescribed a lot), then remember to space out your doses, something like 300mg every 45-60min. It's a waste otherwise.
 
plonk-ozoid said:
I normally take my gabapentins (the morning dose) with breakfast with coffee. If you get jittery from coffee gabapentin won't really help with that, but it's not making it worse either.

If you're taking more than the prescribed amount (or if you're been prescribed a lot), then remember to space out your doses, something like 300mg every 45-60min. It's a waste otherwise.
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Yeah, I normally take about 3000mg/day but my doctors send my prescriptions for it post-dated (meaning they send several prescriptions at once with the date on them for the pharmacy to dispense them), normally a 14 day prescription every 14 days. But for 2 months recently they sent those 14 day prescriptions to be given every 7 days so I've amassed a lot and have been taking in the 4800-6600mg range.
I sometimes will take a handful (like 10 x 300mg pills at once) but after that I stagger one 300mg every hour or so.
 
I used to love having gaba around for H wds. Also, maybe contrary to popular opinion but most stimulants helped me with the lethargy. I used to take lisdexamphetamine in the mornings for the first few days (along with a nice balance of downers too though mind).
 
Believe it or not, dopaminergic stimulant meds actually help opioid withdrawal

Gabapentin or even better Pregabalin plus low dose benzodiazepine (Valium 10mg) or even a Clonidine 0.1mg tablet work wonders….but the best would be:

Pregabalin 150/300/450mg (depending on body weight & tolerance)
Diazepam 10mg X 2-3 tablets daily (1week approximately)
Ritalin 10mg X 2-3 daily
Clonidine 0.1mg an hour prior to bedtime (5+ hours after last stimulant) potent anxiolytic & sedative

All three of these compounds work amazingly together, potent anxiolytic properties + muscle relaxation & anticonvulsant effects….the dopaminergic stimulant works wonders for RLS and provides the essential mood-boosting properties, increased energy and eliminated depression & doom from opioid withdrawal

Mu-agonist opioids & dopaminergic stimulants both target the same centre of the brain responsible for pleasure & reward. A therapeutic low dose would be very comforting combined with the Pregabalin & Valium
 
Would imagine makes you feel 'better' when stims are in full flow, and a gentle mood lift perhaps in low doses as soemone posted well about above

However - there is no way I would want to be on a stimulant comedown while in opiate withdrawal. Fuck that!

So, pro's and cons, as per.
 
The mental depression and super low physical energy from opioid withdrawal……Ritalin (Methylphenidate) would be the best dopaminergic stimulant with its robust mood-boosting properties, safe cardio profile and enhanced vigilance and increased energy.

Diazepam 10-20mg
Pregabalin 150-300mg
Ritalin 10mg X 2-3 daily
Methadone 2.5mg - 5mg once every morning for a week , down to 2.5, 1, then 0.5mg …done (optional)
Clonidine 0.1mg hour before bed
 
Lol dude @Dextro .45 you always are around the corner with your hair-trigger drug suggestions. I can laugh because you remind me of myself when I was younger. I don't doubt I would've said something similar. The combinations you recommend would anesthetize most normal people out there. Not all people are on our level man ;)

I don't recommend stimulants during Opioid withdrawal. In general, they make everything worse. Anxiety, sweating, nervous tics all of that stuff.

I would just say take the Gabapentin and if that actually makes you feel better, you can take some caffeine.
 
Ha ha ha.....ahhhh. I'm sorry bro lol. Honestly, I'm half lit when I come on so ya, my ADHD impulsiveness fueled by a similar cocktail listed above...yaaaa....fair enough

And I'm not suggesting a strong stimulant cause ya, that would be very uncomfortable......BUT.....a very low therapeutic dose of let's say Tramadol Ritalin 5/10mg would completely do good.....paired with Pregabalin & Diazepam. All low doses. It's just I've used these many times myself and I know it has a positive impact on symptoms.

That gave me a chuckle though lol....nice.
 
I’m coming off kratom right now and this conversation is epic.. using yalls info for sure and have scripts for everything suggested lol… thanks youuu
 
However - there is no way I would want to be on a stimulant comedown while in opiate withdrawal. Fuck that!
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I don't recommend stimulants during Opioid withdrawal. In general, they make everything worse. Anxiety, sweating, nervous tics all of that stuff.
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In my own experience, stimulants while suffering from opiate WDs are a fucking nightmare. I'm a little amazed that others have had good experiences - just shows the difference in how people react to substances!

I basically only had negative effects from doing this. It might be because my WDs have always come after years of daily use at fairly high doses and thus I'm at a kind of 'beyond help' point, but the anxiety and restlessness just get much worse with stims and the worst part is the it makes the RLS and insomnia somehow even worse than it already was. Pure torment.
 
Dextro .45 said:
The mental depression and super low physical energy from opioid withdrawal……Ritalin (Methylphenidate) would be the best dopaminergic stimulant with its robust mood-boosting properties, safe cardio profile and enhanced vigilance and increased energy.

Diazepam 10-20mg
Pregabalin 150-300mg
Ritalin 10mg X 2-3 daily
Methadone 2.5mg - 5mg once every morning for a week , down to 2.5, 1, then 0.5mg …done (optional)
Clonidine 0.1mg hour before bed
Click to expand...
Would this same dosing schedule work with buprenorphine?
 
Sure it could....any low dose, long acting substituted opioid would suffice....Methadone would be best IMO ....even 5mg daily, then 2.5 week after, 1mg week after, 0.5mg week after, then every 2 days 0.5mg

Clonidine 0.1mg tablet are a God send.....probably the most valuable drug required
Diazepam 10mg awww that beautiful muscle relaxation & anxiolytic effects
Pregabalin 150mg essential comfort compound
Ritalin 10mg after your comfortable from other drugs, the increase in Dopamine & Norepinephrine will provide the needed mood-boosting & antidepressant effects

Side note.....I took Tramadol as an Opioid naive person 20 years ago....perfect atypical weak opioid with antidepressant properties Serotonin & Norepinephrine properties

Add a safe dopaminergic stimulant like Ritalin with boost Dopamine 3-4X in the CNS and add an Oxy-IR 5mg for added euphoric pleasure

If you're knowledgeable about the complete pharmacological profile of every drug you take, DDI's etc, and a tolerant healthy individual, using safe, low therapeutic doses....there's is a VAST list of beautifully formulated oral drug cocktails / hybrid specialized Brompton Cocktails ....and can be tailored for any need. An anxiolytic cocktail....analgesic painkilling cocktail, a mood-boosting / antidepressant cocktail providing modest euphoria, confidence with pleasurable pro-social properties
 
Dextro .45 said:
Sure it could....any low dose, long acting substituted opioid would suffice....Methadone would be best IMO ....even 5mg daily, then 2.5 week after, 1mg week after, 0.5mg week after, then every 2 days 0.5mg

Clonidine 0.1mg tablet are a God send.....probably the most valuable drug required
Diazepam 10mg awww that beautiful muscle relaxation & anxiolytic effects
Pregabalin 150mg essential comfort compound
Ritalin 10mg after your comfortable from other drugs, the increase in Dopamine & Norepinephrine will provide the needed mood-boosting & antidepressant effects

Side note.....I took Tramadol as an Opioid naive person 20 years ago....perfect atypical weak opioid with antidepressant properties Serotonin & Norepinephrine properties

Add a safe dopaminergic stimulant like Ritalin with boost Dopamine 3-4X in the CNS and add an Oxy-IR 5mg for added euphoric pleasure

If you're knowledgeable about the complete pharmacological profile of every drug you take, DDI's etc, and a tolerant healthy individual, using safe, low therapeutic doses....there's is a VAST list of beautifully formulated oral drug cocktails / hybrid specialized Brompton Cocktails ....and can be tailored for any need. An anxiolytic cocktail....analgesic painkilling cocktail, a mood-boosting / antidepressant cocktail providing modest euphoria, confidence with pleasurable pro-social properties
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Can’t get my hands on methadone unfortunately. Dealers gone and just bupe from the doc. Dont want to start to go to a clinic, yet..
 
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