Bupe Will IV suboxone "block" other opiates for a lesser amount of time compared to SL?

[velocity92c]

Will IV suboxone "block" other opiates for a lesser amount of time compared to SL?

*disclaimer* I know that Suboxone doesn't technically "block" other opiates, and that its blocking effect is because of its very affable hold on opiate receptors, please no corrections.

That being said, I'm wondering if the blocking effect last a smaller amount of time if you IV it instead of taking it SL? I'm going to a party tomorrow night and would like to be able to feel some opiates, I have 2MG of suboxone to do beforehand, and while I prefer to do it SL, I will IV it if the 'blocking' effect doesn't last as long. I will probably be good to go either way as the party is ~30 hours away, but I figured I'd check anyway. I'm looking for a quick answer, which is why I posted outside of the Suboxone thread. Feel free to merge into the mega thread if necessary. Thanks!

 

[comatoserct]

Sorry I can't give you a direct answer, but I can tell you that I personally IV my suboxone and if I were to take 2mg IV I would definitely be able to feel opiates 30 hours later, definitely not to their full extent, but I would definitely get a quality high.

 

[amapola]

There won't be much difference.
However the drug gets into your bloodstream it's all pretty much the same once it gets in there.

IV administration is likely more efficient compared to buccal so more drug may get into your system which makes the effects last longer.

 

[madskilz]

Umm yeah, suboxone blocks other opiates.

 

[Captain.Heroin]

Umm yeah, suboxone blocks other opiates.

No, it doesn't. Plenty of people can take Suboxone/buprenorphine, and then get high on opiates.

 

[SkagKush]

no one really answered his question...........from my understanding IV bupe will wear off faster than SL.....so yes, in theory it will lesson the "blocking" period.....

 

[madskilz]

No, it doesn't. Plenty of people can take Suboxone/buprenorphine, and then get high on opiates.

Maybe they do a little bit?
Are you speaking from personal experience?

 

[Captain.Heroin]

Maybe they do a little bit?
Are you speaking from personal experience?

Yeah. For the first 3 months on Suboxone I would switch from sublingual Suboxone to heroin use, and then back. I still got just as high as I wanted to, and only had to wait maybe 6 to 8 hours. The problem with doing this is that if you do this switch too many times, it may not work as well.

I have also gone from IV buprenorphine to heroin and back but less often, I have less of an interest in using full agonist opiates to be honest with you.

 

[madskilz]

[From Wiki:
Buprenorphine itself binds more strongly to receptors in the brain than do other opioids, making it more difficult, regardless of the presence of the naloxone, to become intoxicated via other opioids when buprenorphine is in the system. If enough buprenorphine is in the system, however, it has the same type of effect as naloxone, i.e. it completely or nearly completely blocks or reverses opiate effects from other opioids.]
Also:
[It (suboxone) has partial agonist activity at the µ-opioid receptor, partial or full agonist activity at the ORL1/nociceptin and δ-opioid receptor, and competitive antagonist activity at the κ-opioid receptor.

An old homie that was taking a high dose of suboxone a day and without a doubt could not get high off heroin during that time, did some research about fentanyls ability to supersede bupe, scored some and found it to be true (he got high). I dont believe placebo had any affect in his findings (Oh, googling bupe and fentanyl mix will get multiple different "yahoo answers" that are completely contradictory. Made me lose a bit of faith in those yahoo answers.)

Wiki is not the end-all-be-all but sounds to me like it certainly can block other opiates.

I have done some research now, but before, my determinations about bupe being an antagonist was because I didn't realize my tolerance got raised so much by the maintenance dose of bupe they put me on that I would've needed a much larger shot of dope to get high than I had done before. So I was guilty then of lack of- or counterfactual information.

 

[Tony Williams]

I was doing Heroin the other day IV and able to catch some buzz. I woke up and did 2mg nasally of Bupe that night I was unable to get ANY buzz from Heroin I shot over a bag and when I did get the high I had overdose symptoms (anxiety and sickness). This morning still no buzz (which was 24hr). After tea I will try more but probably lay off till tomorrow morning (48hr)

When I used to be on 6mg I could still catch a good Oxy/H buzz I guess it builds up over time.

IME. It's very difficult to be on Bupe script and use at the same time - it's annoyingly awkard and even days after it WILL still affect you. I guess it's a good thing as at the end of the day you cant enjoy it so you leave it.

Once I taper off this I wanna just get opiates every 2 weekends and enjoy like the old days before I got into OC quite heavy. If I still can't I'll probably go with methadone.

 

[Captain.Heroin]

[From Wiki:
Buprenorphine itself binds more strongly to receptors in the brain than do other opioids, making it more difficult, regardless of the presence of the naloxone, to become intoxicated via other opioids when buprenorphine is in the system. If enough buprenorphine is in the system, however, it has the same type of effect as naloxone, i.e. it completely or nearly completely blocks or reverses opiate effects from other opioids.]
Also:
[It (suboxone) has partial agonist activity at the µ-opioid receptor, partial or full agonist activity at the ORL1/nociceptin and δ-opioid receptor, and competitive antagonist activity at the κ-opioid receptor.

An old homie that was taking a high dose of suboxone a day and without a doubt could not get high off heroin during that time, did some research about fentanyls ability to supersede bupe, scored some and found it to be true (he got high). I dont believe placebo had any affect in his findings (Oh, googling bupe and fentanyl mix will get multiple different "yahoo answers" that are completely contradictory. Made me lose a bit of faith in those yahoo answers.)

Wiki is not the end-all-be-all but sounds to me like it certainly can block other opiates.

I have done some research now, but before, my determinations about bupe being an antagonist was because I didn't realize my tolerance got raised so much by the maintenance dose of bupe they put me on that I would've needed a much larger shot of dope to get high than I had done before. So I was guilty then of lack of- or counterfactual information.

It's a dose-dependent reaction if buprenorphine can prevent other full agonist opiates from taking effect.

If you use a large dose (32mg sublingual for instance), you aren't likely to feel other full agonist opiates.

However, if you just use 2mg sublingually, or 0.5mg IV, you can at any point, take full agonist opiates, and you'll feel them.