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What would happen if you were never not high on opiates?

T

Tryptomaniacs

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Okay so imagine you are rich and have access to any strength opiate in 100% purity at any time and you will NEVER run out?

When i first started usinng opiates is when my life was at its best point i was in a downward spiral and i got introduced to opiates starting with tramsdol moving to codeine and then hydrocodone, once that was gone i switched to kratom and then later tried tianeptine and ive been off those for awhile now but as i was using i was extremely productive i excersized everyday, i ussually do t eat enough br on opiates i was eating plenty and had the morivation to cook things that werent easy mac and ravioli,
I had a great relationship everyday felt perfect, i had zero anxiety, i could sleep well every single night, i always felt amazing.

Okay, okay you guys get it this is obviously why i got addicted to them, anyways imagine if you never stopped taking opiates (orally only) you had enough of them to raise doses if you had to, switch ti stronger ones and all of the above that opiate addicts struggle with cuz they never have enough, imagine you live your whole like NEVER exeriencing a withdrawl because you are never not high on opiates?

Obviously this is not possible for probably anyone but other than occasional vomiting, are there any long term side effects of this? Again i know its not possible but if it was? The only problems i see with opiate addicts are when they are withdrawling take that out and i say they are pretty safe drugs in right doses.

Ofcoarse there is the chance of overdose as well other than this what side effects could you get from always being high on opiates untill the day you die? Would you die younger? What would happen? Anyone know?
 
Speaking long-term, opioids mess with hormonal balance and they also affect the immune system. At least opiates do, I think fentanyl et al do not do that to a significant extent; I could be mistaken, but it may be mu3 receptor activity that is responsible for the aforementioned.

In any case, I wouldn't want to do that. I basically have the resources to afford a habit, but it's just not for me, which is why I stick to doing codeine. My work requires cognition (I do scientific research), and even though opioids practically do not impair one's cognition if not too high, they still do affect it, which is why I never get high before doing work, I always do it sober. So this makes it a problem - I don't want to be withdrawing while working, which means I have to keep my tolerance fairly low. So I stick to codeine.

If I didn't work though, then perhaps I'd give it a try (assuming I can afford it), but I think I would get bored fairly quickly. The high does, after all, get less and less enjoyable the longer you use.
 
I lost interest at the words "oral only", that can't say anything good about me... Lol

Ok so long term problems? My understanding is that eventually you would reach a point where you are out of receptors, and tolerant to a point where you're basically stuck at a normal non-high which can't be escaped without going allllllll the way down again. I'm no expert though so I may be wrong about this.

Other than that who knows, maybe eventually organ damage will occur even though it would never normally happen?

Might make an interesting research experiment on animals....
 
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Always being high would make you not high. Because high is relative, higher than "normal," and if normal is high then high is normal. Right?
 
SirTophamHat said:
Always being high would make you not high. Because high is relative, higher than "normal," and if normal is high then high is normal. Right?
Click to expand...


BOOM holy shit mind fucking blown thats so true, BUT if normal is always feeling amazing then id enjoy being normal!

But yeah i agree the tolerance would be absolutely insane but then id assume just use other drugs if you want a different high ir are bored but yeah im sure it wouldnt be great for the body ive never used any opiate stronger than hydrocodone well except for a strong poppy seed tea and at the hospital i got IV fentanyl whitch was amazing but i was in pain so not that great. But i would deffinetly move um very slowly switching to morphine then oxycodone eventually trying hydromorphone then oxymorphone then i would try both and decide whether i wanted to do heroin or fentanyl and then once my tolerance was EXTREMELY high id move to intense shit like carfentanyl haha this would be a poor idea now that im thinking about it honestly id be happy smoking opium and eating morphine everyday i will snort drugs but dont like to. Hell ill even plug but ill never iv or im jnless a doxtor or a trained person is doing it for me with sterile shit
 
I'd prob STILL have a full time corporate gig in Software Sales or Recruiting Manager (I was both at a point) but ended up losing jobs due to DUI's (both coming from drugs/alcohol) and then having to constantly leave work for weeks at a time for rehabs, arrests, programs which I had to attend even w/ a full time job, etc. also spent all the savings, money, everything ever made from jobs that had good income, so its a damn shame; now I find myself working general labor and barely squeaking by on Suboxone; was it worth it? no, because my record sucks and my corporate life has a hold on it for now till I figure out my next best move because my overall health sucks.
 
I would be content with my life, as long as I could also never run out of methamphetamine and benzodiazepines. The holy trinity, completes my life. Really, I'd sell my soul for this.
 
JessFR said:
I lost interest at the words "oral only", that can't say anything good about me... Lol

Ok so long term problems? My understanding is that eventually you would reach a point where you are out of receptors, and tolerant to a point where you're basically stuck at a normal non-high which can't be escaped without going allllllll the way down again. I'm no expert though so I may be wrong about this.

Other than that who knows, maybe eventually organ damage will occur even though it would never normally happen?

Might make an interesting research experiment on animals....
Click to expand...

Opioids are fairly unique, at least the well-researched ones, so the opiates and the semi-synthetics, in that they're practically harmless to organs (I can provide sources if you're interested). The only long-term problems as far as I know are the hormonal disturbances as a result of mu3 activation AFAIK, so opiates a la morphine et al do that, but fentanyl and other selective non-mu3 agonists don't, and immunosuppression as a result of opioid activity as well. I know that some kind of cells in the immune system have opioid receptors, which is the reason for immunosuppression of morphine, but I don't know what subtype of receptor that is off the top of my head, so it is possible that perhaps more selective opioids (again, fentanyl et al?) would lack that problem. But yeah, long-term opioid use, unless it is really extreme, is pretty much harmless. Withdrawal is perhaps the most damaging condition to the body.

But you're right. Being "high" all the time will destroy your receptors, so at some point you will just feel normal on the same dose as before. I don't know how high you can go with the dosages (tens of milligrams of fentanyl?), but raising your tolerance that high is never a good idea unless you're really planning on not spending even one day without opioids, for the rest of your life. This is actually the main reason I try to maintain a low level of dependence/tolerance, because I want to be able to go a couple days without taking any if necessary and not be a complete mess. And of course, going into heavy withdrawal on a daily basis is not good for the body either.

Following opinion is not heavily based on scientific fact, but I think an opioid dependence is less damaging/harmful than a benzo dependence of the same severity. I'm somewhat moderately dependent on opioids (codeine at this point), but I really don't want to even think about what benzo dependence would be like. If anything, a week of suffering and I'm done with the w/d, but benzo w/d can last months, or even years. No thanks, buddy. Plus a significant portion of benzos are known (?) to be carcinogenic and possibly otherwise harmful on their own. Not accounting for withdrawal, of course. Benzo withdrawal can be severely harmful for many parts of the body, especially the brain (yay for excitotoxicity!).
 
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I would like to take them forever but even though theyre rather harmless to the body in pure form I dont see that as the main disadvantage. Its the emotional plateau that you hit when youre on them(which changes you). When your life is unbalanced or your unhappy they can be the best thing in the world and I loved taking them for ...too long. But once you either been taking them too long or have your life in order, if you somewhat clear your mind you see the distance they create from the world. For those empiric scientific types this might be mumbojumbo but the vibe or the energy is completely different when you dont use. The feeling of being alive is completely different. I love hiding from the world with them and in todays world its extremely difficult to be even content with your life due to all the cr+p but if you find the balance, you see how opiates destroy it. Its like eating healthy good food for a month and then driving past Mcdonalds. Some ppl will always see it as a treat and crave it, some see the lightness and the good from the healthy food and the McD will start to smell like sh+t and theyll drive past.
 
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