Two dead from nitazines

[Ismene2]

Looks like the pills I took - these guys must've thought it really was oxycodone.

Warnings have been issued by a west London council and nightclubs after two people died in suspected drug overdoses from highly potent synthetic opioids.

An investigation is under way into the "sudden deaths" of a 28-year-old man and a 20-year-old woman in Southall on 26 May, the Metropolitan Police said.

"This is following reports that the individuals allegedly passed away after taking an illicit substance in the form of a green pill," a spokesperson for the force added.

Drug testing charity The Loop has said the pills contain synthetic opioids called Nitazenes, which can be "50 to 500 times stronger than heroin".

Ealing Council said the two people who died are understood to have taken green pills with the number 80 on one face and possibly an "OP" on the other.

Warning issued over two suspected Southall opioid deaths

A woman, 20, and a man, 28, died from suspected overdoses after taking high strength opioids.

www.bbc.co.uk

 

[just a coker 01]

Nasty !

 

[F.U.B.A.R.]

Now is not a good time to use opioids.

 

[just a coker 01]

Glad im not a opiod user, ill stick with my rum for when i am coming down off the crack,

 

[Gaz_hmmmm]

You can tell they're fake OxyContin/LongTec/whatever ever other brand's are licensed copies of the original Purdue (US)/NAPP (UK) OxyContin's cause the colour isn't dark enough and they look crumbly.

I don't understand why nitazenes are going around loads in fake/counterfeit benzo's, pregabalin, zopiclone and Oxy's but doesn't seem as common in actual street Heroin when it's street Heroin user's who'd prefer them?

 

[4DQSAR]

I do keep posting this but will continue to do so in the hope we can all share data,

Real Oxycontin tablets (and all of the generics I have been prescribed) have a thin coloured layer (specific colour dependent on potency) over a white core. All of the fakes I've heard of are a solid colour right through the tablet.

Now this in no way proves that a given tablet is genuine, but it it's the same colour right through, I think you can reasonably assume it to be a fake.

Snap, look, refuse.

 

[Zopiclone bandit]

Glad im not a opiod user, ill stick with my rum for when i am coming down off the crack,

That is till the moment you Die from Cocaethylene.
I know two people who have Died from doing what you are making sound a good idea.

"Cocaethylene is the byproduct of concurrent consumption of alcohol and cocaine as metabolized by the liver. Normally, metabolism of cocaine produces two primarily biologically inactive metabolites—benzoylecgonine and ecgonine methyl ester. The hepatic enzyme carboxylesterase is an important part of cocaine's metabolism because it acts as a catalyst for the hydrolysis of cocaine in the liver, which produces these inactive metabolites. If ethanol is present during the metabolism of cocaine, a portion of the cocaine undergoes transesterification with ethanol, rather than undergoing hydrolysis with water, which results in the production of cocaethylene."

 

[4DQSAR]

From the studies I have read, the transesterification of cocaine appears to vary widely between individuals. Only a small perecentage of any cohort study showed significant transesterification. That said, ethanol has been shown to slow down the metabolism of both cocaine and any cocaethylene formed in vivo. A couple of studies suggest that cocomminent use of cocaine and alcohol increase the risk of sudden cardiac death by an order of magnitude at least.

It's one of those things where you can drink heavily after using cocaine and be fine for years. Right up to the point when you drop dead.

I've only witnessed it once - a NYE party in Amsterdam. Guy next to me had been drinking vodka and railed a big line off the top of a speaker. Guy went down like a sack of shit. We all thought it was a wind up for a moment but luckily a few of us were sober and went on with CPR. Sadly it didn't work - but we tried. I mean, you ALWAYS try even when you know the odds.

The thing is, I've looked at various forensic journals and quite often they will suggest that cocaine was a 'contributing factor' in a death so we may well be hugely underestimating the deaths caused by cocaine. Because of how it kills, unless there are very clear signs, a pathologist will not outright state 'cocaine poisoning' because it's harder to show the direct cause and effect. With opioids, people stop breathing so it has VERY clear and well understood signs such as low levels of oxygen in the blood. SCD doesn't give anything so clear.

I don't like cocaine so it's never really concerned me beyond my occasional bits of work for the various HR agencies. I DID highlight that diagnostic issue but until we understand why cocaine, alcohol and SCD are associated and how we can show a causal chain, it's all vague. You cannot model it very weill in animals.

But having seen it, I tend to suggest people stick to lager or something that sort on the basis that the volume of fluid at least gives the body the chance to flush the cocaine and metabolites out. Spirits may be more hazardous since they will tend to dehydrate thus concentrate the cocaine and it's metabolites. I dunno, if someone wants to drink, I can't stop them, but if I suggest lager might be safer, many will say 'well, OK, lager it is'.

The latest data suggests alcohol slows down the metabolism of cocaine. I know that when people mix alcohol and cocaine, I try not to be there. Some people are fine, some can be rather unpredictable. I don't want to end up in a fight because someone I was sitting with thought the bloke on the next table gave them 'a funny look'.

What we DO know is that after alcohol, cocaine is the most common drug detected in people arrested in the UK. Now I have no idea what's going on with that.

I SUSPECT genetics plays a key part. In the transesterification of cocaine. the metabolism of cocaine and the toxicity of cocaine. But I doubt we will ever have a genetic test for those at risk in my lifetime.

 

[Bleaney]

What we DO know is that after alcohol, cocaine is the most common drug detected in people arrested in the UK. Now I have no idea what's going on with that.

I have an idea. Alcohol and cocaine bring out the worst in some people. Either seperately or combined.

Inhibitions lowered, confidence and ego heightened too much, judgement impaired (if they even ever had any to begin with), and if certain individuals have underlying tendencies towards violence or aggression, or driving UTI in a way that it is going to attract the attention of the police, or any other sort of behaviour that can you arrested, then it doesnt surprise me.

Plus cocaine is probably very widely available and accessible for large sections of the population.

 

[4DQSAR]

Yeah - it's a mixed bag of results.

 

[Ismene2]

I just scraped a bit off dust under my thumbnail and licked that and I was uncomfortably high. Im surprised more havnt died with that silly bastard selling them as "oxycodone"

 

[Bleaney]

If it's just one vendor in particular that you know of that is selling these deadly pills, is there no way of reporting them to the DNMs they operate on?

I'm assuming this is your source.

'Silly bastard' doesnt quite cover what he/she/they are doing, and neither does the word "unethical" that I was going to call them. "Murderers" would be more fitting, but w/e words we use to describe them, they are at least guilty of man-slaughter.

Please at least leave negative feedback advising that they are selling deadly nitazenes and people are dying.

 

[4DQSAR]

Well - snap a pill. If it's a solid colour right through, it's likely fake.

That doesn't mean one can assume that the bicolor format ensures it IS oxycodone, but calling out fakes sooner rather than later is important.

 

[Ismene2]

If it's just one vendor in particular that you know of that is selling these deadly pills, is there no way of reporting them to the DNMs they operate on?

I'm assuming this is your source.

'Silly bastard' doesnt quite cover what he/she/they are doing, and neither does the word "unethical" that I was going to call them. "Murderers" would be more fitting, but w/e words we use to describe them, they are at least guilty of man-slaughter.

Please at least leave negative feedback advising that they are selling deadly nitazenes and people are dying.

There's lots of reviews saying its not oxycodone its nitz - the guy who took it must've bought it from someone else - unless he never looked at the reviews. It was like a stupid price too - like 5 oxycodones for £15. They're usually one oxycodone for £25 or something.

 

[4DQSAR]

I keep an eye on www.streetrx.com and as recently as 6 months ago prices ranged from high to ridiculously high. It appears to have settled down now but at an eye-watering price for what I conclude are real pills. Of course, who knows the veracity of any streetrx report? Sellers could just as easily report high prices to justify continued sale at such prices. I have only ever seen one or two examples of prices that appeared too low although a BLer mentioned that most people still don't know what it is and don't want it.

But I can well imagine the UK taking the step of adding naloxone to oxcodone tablets to at least prevent parentheral abuse.

As I have told every HR agency I'm in contact with, tell potential buyers to snap a pill - it the colour is solid right through the pill, it's a fake. If nobody will buy fakes, maybe we can stop people trying to introduce nitazenes.

 

[Curt Mandible]

It’s wild how some pills out there look like regular stuff but are actually super dangerous. People need to be extra careful and maybe get stuff tested if they’re gonna take anything at all.

 

[4DQSAR]

It’s wild how some pills out there look like regular stuff but are actually super dangerous. People need to be extra careful and maybe get stuff tested if they’re gonna take anything at all.

Do they? Real pills, or at least thoose encountered in the UK have a thin coloured layer over a while core.

Hence if you snap one and it's a solid colour all the way through, it's aa fake.

That does't preclude the posibility of someone eventually managed to emulate that security feature so yes, always tests, but if potential buyers can spot-test and resuse based on visual evidence - that will make the street value of fake zero.