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  • BDD Moderators: Keif’ Richards | negrogesic

Tramadol question

V

Virgogirl619

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Joined
Jan 12, 2024
Messages
17
I know most on this forum are not a huge fan of tramadol. I however really likes them. I actually prefer them over my oxy prescription. I've been on them for 10 years and the dose I take is insane and most people would say that I'm lucky I haven't died of a seizure. With that said I would like to see if there's any way to increase bio availability with them. my tolerance is through the roof and I'm tired of blowing through my prescription in 10 days
( 240 a month if that tells you anything). Luckily, I have an oxy prescription that I switch to when I run out of tramadol, but like I said, I prefer the tramadol and would like a way to basically get more bang on them. Any thoughts?
 
I mean, there are things you can do to make them stronger, but i really dont want to encourage you to take this much tramadol. Have you thought about getting a weak dose of an SNRI for when you don't have any tram? If that gets you what you want when combined with oxy, it would be worth switching off of them full time. Don't expect you take that from me though. Mostly though, ODSMT is what you're feeling, so you'd want to look into the enzyme that metabolizes that, (probably cyp2d6, and if so, there is fuck all for inducers. Valerian is a weak one) and then get an inducer of that enzyme to increase the metabolism.
 
Better yet, ODSMT is less dirty and an unregulated drug, (I think it still is) also much less toxic.
 
ODSMT is great. It's not particularly strong (if you have a tolerance and/or are using opiates daily) but it's nice. I wish I could still get it. Australia blows.

Virgogirl - you get prescribed 240 tramadol a month AND an oxy script? Holy shit. The USA is wild. Doctors in Aus will literally tell you to take some paracetamol (acetaminophen) for anything less than a severed limb. Some friends and family here have been told to take paracetamol for post surgery pain. It's the opposite extreme to America's situation.
 
Halif2 said:
ODSMT is great. It's not particularly strong (if you have a tolerance and/or are using opiates daily) but it's nice. I wish I could still get it. Australia blows.

Virgogirl - you get prescribed 240 tramadol a month AND an oxy script? Holy shit. The USA is wild. Doctors in Aus will literally tell you to take some paracetamol (acetaminophen) for anything less than a severed limb. Some friends and family here have been told to take paracetamol for post surgery pain. It's the opposite extreme to America's situation.
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Some states are better with chronic pain than others, I happen to live in an area that is OKIsh but I have a very good doctor. I have a legitimate diagnosis for the medication im prescribed although I obviously don't take it as directed. I do approximately 10 days of tramadol and then the rest of the month with my oxy.
 
Virgogirl619 said:
I know most on this forum are not a huge fan of tramadol. I however really likes them. I actually prefer them over my oxy prescription. I've been on them for 10 years and the dose I take is insane and most people would say that I'm lucky I haven't died of a seizure. With that said I would like to see if there's any way to increase bio availability with them. my tolerance is through the roof and I'm tired of blowing through my prescription in 10 days
( 240 a month if that tells you anything). Luckily, I have an oxy prescription that I switch to when I run out of tramadol, but like I said, I prefer the tramadol and would like a way to basically get more bang on them. Any thoughts?
Click to expand...
1200 mg a day, with a cold cut at day ten, every month? I was on Tramadol daily for just shy of 12 years, the first two of which was 400 mg a day, the latter 9 were at 300 mg a day. I never developed any real tolerance issues, for for most part. Interesting, I will concede that the oxy easily fills in for the opioid portion of Tramadol, but the ssri portion at that dosing is massive, and I really am surprised that you get by with that cold cut for twenty-days each month.
 
That is an insane amount of tramadol in a short period of time. Not judging cause it sounds like you need them, just yeah, be careful.

If I were you I would not take all my tramadol in ten days and then only have oxy for twenty. You could try and disperse your doses more evenly across the month. You might not feel like you're missing something as much for most of the month, because you would have a more stable level throughout. And yeah at that level it's basically acting like an antidepressant.

And yes, odsmt or maybe kratom are options too, but honestly, with that amount of tramadol and oxy, you really shouldn't be taking more opioids in any form, I can't imagine they would even be as effective as they should be.

Is there any way you could cut back for a little bit and then maybe bring your tolerance down some? Tolerance is probably a huge factor. If you take the bare minimum dosage you need to function, for a couple weeks or a month, your tolerance might level out slightly, and also you'll find yourself with a surplus of meds, not running out a week into your script. That's a win-win in my book.
 
Halif2 said:
Virgogirl - you get prescribed 240 tramadol a month AND an oxy script? Holy shit. The USA is wild. Doctors in Aus will literally tell you to take some paracetamol (acetaminophen) for anything less than a severed limb. Some friends and family here have been told to take paracetamol for post surgery pain. It's the opposite extreme to America's situation.
Click to expand...
I was genuinely astonished that any doctor was prescribing that in America when I read that. It's not great for most people out here for pain pills. Like, you'll get 10 codeine 3s for getting your wisdom teeth removed, or minor car wrecks and broken bones. I have a friend who's mom had cancer removal surgery on her head (outside the skull, but still) recently in the midwest. The doctor said to take ibuprofen. Just for perspective.
 
deficiT said:
And yes, odsmt or maybe kratom are options too, but honestly, with that amount of tramadol and oxy, you really shouldn't be taking more opioids in any form, I can't imagine they would even be as effective as they should be.
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Great point, I was trying to suggest ODSMT as an alternative rather than an additive to the tramadol.
 
How do you take your doses Virgogirl?

Stacking tramadol will give you better pain relief. Meaning you take 1 pill, wait about 20 minutes & then take your next pill & so on until you reach your desired dose.

O-desmethyltramadol is the metabolite of tramadol & what gives most of it's opioid effects. Your body can metabolize tramadol better when you already have a little tramadol in your system. So you might find that by stacking your doses, you might be able to get away with using slightly less or even getting enhanced pain relief from them.

Taking your dose all at once is less effective & increases your seizure risk.

I was on tramadol for 10 years as well. Every single month of those 10 years, I went through tramadol withdrawal. They were my moms pills, but she always just gave them to me. I preferred tramadol over oxy as well. With no to low tolerance, tramadol had me itching & nodding in a very similar fashion to heroin. I never got much out of oxy like that, but I've had limited experience with oxy honestly.

I never found anything that really enhanced tramadol in those 10 years either, other than adding more opioids on top of it.
There is an extended release version of tramadol, if you think you'd feel comfortable enough talking to your doctor about doing that. I had a bottle of the extended release kind of once & they were pretty nice. Had me nodding & sedated for at least 8-12hrs.

Unfortunately there's not much else that will really make tramadol any better, besides stacking or taking a tolerance break.
Gabapentin might be able to help if you can get your hands on that.

I'm envious of anyone with a script for TWO opioids! lol But I definitely don't envy whatever pain you're having to deal with, so I wish you the best of luck!
 
Pregabalin ( not high dose ) and caffeine enhance tramadol effects ( both speedy, anti-anxiety and noddy part )
 
Virgogirl619 said:
I know most on this forum are not a huge fan of tramadol. I however really likes them. I actually prefer them over my oxy prescription. I've been on them for 10 years and the dose I take is insane and most people would say that I'm lucky I haven't died of a seizure. With that said I would like to see if there's any way to increase bio availability with them. my tolerance is through the roof and I'm tired of blowing through my prescription in 10 days
( 240 a month if that tells you anything). Luckily, I have an oxy prescription that I switch to when I run out of tramadol, but like I said, I prefer the tramadol and would like a way to basically get more bang on them. Any thoughts?
Click to expand...
Must be something about virgos and high tramadol tolerance, I also used to go through 240(more, actually) in 10 days. But in my years of abuse I never found anything that really gave it any more of an edge, hence such a high dose. The only thing that made tramadol stronger was more tramadol lol

I’d highly advise tapering down. Even if you get this script the rest of your life, I highly doubt they’re going to go much(if any) higher on the pill count and you’re going to be in an endless cycle. An even worse one, actually. I’m sure you’ve noticed already, but tramadol withdrawal doesn’t cease when you switch to a different opiate. I’d be high as fuck on oxy and still feel like shit(honestly I mostly just felt weird af, very uncomfortable but not as bad as opiate WD). Definitely not something I’d want to continue going through every month. Once my “endless” supply ran out I didn’t seek out more, I made the switch to something else cause I knew I’d never find a supply steady enough to support the massive habit I had.

Even with other drugs I still count tramadol as the worst WDs I’d been through, cause I did a portion of it without anything else and they were horrible. I’d strongly suggest getting yourself tapered down enough and rely more on the oxy(IMO they work better for pain anyway) and save up some of the tramadol to party with in smaller doses throughout each month. You’ll be doing yourself a favor in a few different ways
 
daturetard said:
I mean, there are things you can do to make them stronger, but i really dont want to encourage you to take this much tramadol. Have you thought about getting a weak dose of an SNRI for when you don't have any tram? If that gets you what you want when combined with oxy, it would be worth switching off of them full time. Don't expect you take that from me though. Mostly though, ODSMT is what you're feeling, so you'd want to look into the enzyme that metabolizes that, (probably cyp2d6, and if so, there is fuck all for inducers. Valerian is a weak one) and then get an inducer of that enzyme to increase the metabolism.
Click to expand...

First off, this is a very astute observation/suggestion. I had read through OP's post and was thinking the very same thing.

OP, you're asking for trouble. We are a Harm Reduction community and what you're doing is worrisome to myself and everyone else. Tramadol in doses of over 300mg decrease the seizure threshold significantly. It's my belief that you will eventually have a seizure if you continue. Given the doses you're using, it could be very severe. A lot of people wake up from seizures, though a lot of people also die from seizures.

Tramadol is an Opioid agonist like any other. The primary difference in its pharmacology is its role as a Serotonin-Norepinephrine reputake inhibitor or SNRI. There are many drugs in the "antidepressant" market that are SNRI's like Venlafaxine (Effexor) for example. It's possible that an SNRI might benefit you somehow.

There is also the possibility that you have become habituated to high levels of SNRI activity through your Tramadol usage. Bear in mind that SNRI's are known to produce a fairly severe withdrawal syndrome when stopped abruptly. I don't want you to discount the possibility that you are actually relieving symptoms of SNRI withdrawal by taking the Tramadol.

It is possible that you could get what you need by taking Oxycodone with a dose of an SNRI. This would instantly take you into much safer territory. Let me know if you have any questions.
 
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