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  • BDD Moderators: Keif’ Richards | negrogesic

thienobenzodiazepine=benzo? (Olanzapine)

tyler5

tyler5

Bluelighter
Joined
Mar 6, 2005
Messages
480
Location
Tallinn, Estonia
Hello fellow Bluelighters,


I found out that I have been for the last 3 months taking OLANZAPINE also known as HORSESHIT!

My methadone doc wrote me a script for 15mg olanzapines because I had and still have trouble with insomnia
I dont have a clue where the hell he got the idea that this DISGUSTING CRAP could put anyone to sleep is beyond me.

On wikipedia it writes that 40% of its users gain quite much weight.

Thank god he wrote me a script for only olanzapine and not the WORST one which is olanzapine+Prozac.

I have put on 40-50lbs in 3 months and I barely eat enough a day to get 1000 calories or so.
Its just that I work from home in front of my PC and so I am not very active at all physically which is not good, i know, i know. I force myself to go for walks and when I get home after 30 minutes or so I can def. say I feel a bit better after some "exercise haha.

I was baffled when I suddenly started to alarmingly gain weight (all 100% of it in my belly) because I dont eat a lot although I do have a Dr Pepper addiction (2L/67oz per day) which I intend to quit by drinking 0.33L less each day.
Once im free I will reserve a small 0.5L bottle for myself once a month, if that.

My question is: are thienobenzodiazepines (like olanzapine) equal to benzos like diazepam, alprazolam etc?
If so, I could just drop the 30mg/day tomorrow because I take benzos every day already and dont have a problem to take like one 2mg rivotril more to get off this EPIC FAILURE of a drug.

I will eagerly wait for Your opinions.

Thanks in advance.
 
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I've never taken olanzapine but from what I've read it's similar to quetiapine (sp? Seroquel) Personally, I've had awful experiences with Seroquel and Geodon. Not so bad with risperidone. Weight gain is real common with these medications and it was horrible for me

What you might want to do is talk with your doctor and tell them you don't want to take it anymore. In which case, he/she will probably suggest lowering the dose and eventually tapering off. When I got pregnant, my doctor advised me to taper down to where I would take it every other day before dropping off completely.

There might be comparisons or equivalency figures somewhere on the internet that could tell you xx thienobenzodiazepine could be replaced by xx benzodiazepine. But I couldn't find this information specifically for olanzapine. Maybe someone here has personal experience they could share. Either way, it's best to be safe and tell your doctor what's up. Good luck! :)
 
It's an atypical antipsychotic but also falls into the category of theinobenzodiazapine. Here in the U.S. it's known as Zyprexa.
 
Uh not really..

Benzodiazepine basic structure:
152px-Benzodiazepine_a.svg.png

You can see two benzene rings (one one the bottom and one on the left) and one diazepine ring (the one with two N in in it and fused together with the left benzene ring).

Thienodiazepine (etizolam and company) basic structure:
Thienodiazepine_Structure_General.png

It's really the same thing except that one of the benzene rings has been replaced with a thiophene ring (the one on the left with S in it, fused to the diazepine ring).

Thienobenzodiazepine (Olanzapine since I can't find a generic pic):
200px-Olanzapine.svg.png

This has the same 3 rings as the previous picture, but they are arranged in a different way.

The first two classes act in a very similar way (positive allosteric modulators of the GABAA receptors) and are pretty much interchangeable.
The last is an atypical antipsychotic, acts on a whole bunch of receptors and isn't interchangeable with the first two.
 
If olanzapine is a thienobenzodiazepine, i dont think I see the need for a taper.
since i am already on benzos, i could just instead maybe raise my benzo intake by 4mg clonazepam or so.
i mean if you were on benzos and ran all out, and your friend has etizolam, then you can just take that and it will take care of the probllem of having benzo wd.


the main thing i wanted to know was exactly that - are thienobenzodiazepines equal to benzodiazepines and from You're posts I gather that it should indeed be thienobenzodiazepine = benzodiazepine.

If anyone disagrees I would like to know how etizolam which is also a thieno- like olanzepam and you can definitely use etizolam if you run out of regular benzos. i mean etizolam would keep the withdrawal at bay, right? i havent used etizolam myself (i dont think RC benzos are anything special and i can get real benzos for a lot cheaper) but i dont see why it would not work to switch from, lets say, alprazolam/diazepam/lorazepam to etizolam.

to all that havent tried olanzapine, you can take it for a few days but after that it loses all of its potential and you are just taking a VERY crappy benzo that makes you put on weight and all of it goes straight to your belly.

ive been using it for 3 months 30mg and my belly looks like im pregnant or that i drink a case of beer each and every night.

another god damn stupid, old, not-in-the-know psychiatrist that writes me something that should be outright BANNED from the pharmacy (never gonna happen, of course, since olanzapine+prozac is a real popular drug.
i couldnt imagine all the negative side effects of taking a crappy SSRI and this weird thienobenzodiazepine.

At least I am not on that drug, so I can just quit taking the evil Olanzapine and continue my benzodiazepine intake.


heres a link (click) to my other thread where i asked straight up about olanzapine and WD's and going cold turkey. he said that after being on it for YEARS, he just quit and had no problems to speak of. go figure.


If anyone has more opinions or experiences with olanzapine or olanzapine+prozac, let us know. lets find out what kind of poison are the drug reps pushing with their pens, mousepads, big happy-colored posters and so on.
they are even giving samples away for free like you would see in a USA hood when they give all the fiends a free bag to try and hopefully gain a customer.
 
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yes, i did that, thats why i find it strange that ive read of people just dropping the olanzapine and suffering no WD's.
like i mentioned in my last post, i posted a link to a reply from this forum from a guy who had the exact thing: he eventually weighed 250lbs and had type 2 diabetes. once he dropped the olanzapine (and he had been on it for years vs. 2-3 months for me)
everything started to go better. he isnt diabetic anymore and has also lost almost all the weight that he put on during the years of this horrible drug.

i am not saying the poster who explained it scientifically with chemical drawings etc. is not right.
but then again i dont see why would i also get replys that its safe to drop olanzapine overnight and nothing will happen to you.
 
Idk much about antipsychotic wds to really say if you can just stop taking them and feel fine....

But if you got addicted to a benzo you could switch to etizolam (or from etizolam to a benzo) and be fine. But you couldn't just stop with no wds.
 
black53: Yes, of course, I know that and I have been taking benzos for the last 10 years with maybe one full month of being clean (tapered, of course).
At my worst I was taking 12-16mg/xanax a day which equals to 300-400mg valium/day. Also, about the
Olanzapine being an antipsychotic. I have a feeling that almost all of the atypical antipsychotic stuff is meant when You are taking the 2-drug combo which are Olanzapine and Prozac in one tablet.

Olanzapine is probably there to help you relax somewhat and make getting to sleep a little easier but I don't think Olanzapine itself on its own is a full blown antipsychotic. I might be wrong, though, of course - thats why I came here to get some help and knowledge on the stuff. i am going to tonight take 15mg instead of 30mg (1 tab instead of 2) and see how I do the next morning.

If I really have to withdraw from this shit, then i am going to do it first in 5mg increments and once im down to 10-15mg, i will lower 2.5mg weekly.

Now I just hope the doctor writes me some REAL sleeping meds as well - triazolam or brotizolam.
 
Clozapine and loxapine are both dibenzodiazepine and the structure of diazepine is the basis for benzodiazepines yet those 2 drugs certainly have nothing in common pharmacology wise with say diazepam. I have taken olanzapine for bipolar disorder and found it to work great actually but it's certainly nothing like a benzo lol. Mixing it with a benzo like say clonazepam is a good way to knock a manic episode or stimulant induced psychosis right in the dirt though.

But yeah don't try and use anti-psychotics of any kind except for their intended purposes. They are certainly not recreational in any sense of the word.
 
Turk@GG said:
qft!
Click to expand...

Actually olanzapine is a great drug for treating mania and schizophrenia. Giving anti-psychotics to people is hardly a new thing either as Thorazine has been around a long long time. These drugs are good for their intended purposes and i found zyprexa to work great. But then again i wasn't looking for a benzo type feeling either.
 
Maybe so, for Schizophrenia and Manic patients....I just believe doctors these days really deny people meds like actual benzos that can REALLY benefit from them, (maybe out of fear of abuse?) and instead prescribe some drug like this or a laundry list of SSRIs that really do nothing for a lot of people that suffer from disorders like Social Anxiety.
 
It may be able to treat those conditions effectively but it still has horrendous side effects when doing so. Why are benzos not used for mania anyway? They are far kinder and do not have the same anhedonia and undertones of sadism with their use.
 
_DankOpiAmp_ said:
It may be able to treat those conditions effectively but it still has horrendous side effects when doing so. Why are benzos not used for mania anyway? They are far kinder and do not have the same anhedonia and undertones of sadism with their use.
Click to expand...

Benzos are not effective in controlling mania on their own in the long term. They are good at treating acute manic episodes when mixed with say olanzapine or some other anti-psychotic but on their own they aren't that effective against long term mania like you get with bipolar disorder. Anti-psychotics can have nasty side effects for some people but i never got any major side effects from them yet and I've been taking them on and off since 2006. I've mostly been on seroquel but also risperidone, olanzapine and i have also taken good ol Thorazine aka Largactil as well as Compazine/Stemetil and methotrimeprazine. The last 3 i took for either nausea or sleep though.
 
I have found that Olanzapine has been very beneficial to my bipolar disorder, I also have A slight schizophrenic disorder known as M.P.D. I have a varied amo
 
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