• N&PD Moderators: Skorpio | thegreenhand

Ketamine salts solubility

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1-(4-methyl-3-methoxyphenyl)-2-methylamino-1-methoxypropane.png


SAM(SON)
1-(4-methyl-3-methoxyphenyl)-2-methylamino-1-methoxypropane

The Killers, "Sam's Town."
Tobacco Road by Erskine Caldwell
God's Little Acre by Erskine Caldwell
30833

1-(4-bromo-2,5-dimethoxyphenyl)-2-amino-1-ethoxypropane.png


HARRIET
1-(4-bromo-2,5-dimethoxyphenyl)-2-amino-1-ethoxypropane

The Wizard Of Oz (movie)
OZ (HBO TV series)

1 Oz. (ounce) = 28.35 grams
2.54 cm = 1 inch

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JACK
1-phenyl-2-methylamino-1-ethoxypropane

1-(4-sulfhydrylindole-3-yl)-2-dimethylaminoethane.png


SHEOL
1-(4-sulfhydrylindole-3-yl)-2-dimethylaminoethane
 
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1-(2,5-dimethoxy-4-bromophenyl)-2-ethylaminoethane.png


STRIKE
1-(2,5-dimethoxy-4-bromophenyl)-2-ethylaminoethane

1-(2,6-dimethoxy-4-(ethylthio)phenyl)-2-methylamino-1-methoxyethane.png


SHELDON BLUFF
1-(2,6-dimethoxy-4-(ethylthio)phenyl)-2-methylamino-1-methoxyethane

1-(4,7-dimethoxy-6-bromoindole-3-yl)-2-dimethylamino-1-methoxyethane.png


BOB_INDOLE
1-(4,7-dimethoxy-6-bromoindole-3-yl)-2-dimethylamino-1-methoxyethane

Both Bob & Elizabeth Dole Had Natal Leo Suns.
 
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1-sulfhydryl-2,6-diisopropylbenzene.png


SEDATION_VACATION
1-sulfhydryl-2,6-diisopropylbenzene

1-(4-sulfhydryl-3,5-diisopropylphenyl)-2-aminoethane.png


SEDATION_OCCUPATION
1-(4-sulfhydryl-3,5-diisopropylphenyl)-2-aminoethane



1,1,1-tribromo-2,2-dihydroxyethane.png


ETH_NECK (chloral hydrate analogue)
1,1,1-tribromo-2,2-dihydroxyethane

NECK means 'death.'
Please do not wring mine.
Thx! ;)

1-sulfhydryl-2%2C4%2C6-trinitrobenzene.png


STINK_BOMB
designer explosive agent
1-sulfhydryl-2,4,6-trinitrobenzene

2,4,6,8 Whom Do They Appreciate? ME ME ME.

1-phenyl-2-aminoethane.png


SWEET_PEA [P = 8]
1-phenyl-2-aminoethane

Do Your HOMEWORK! by Daft Punk!
Je parle la Francaise juste un peu.



Volume, Of A 3-sphere = 4/3(pi)r^3
Surface Area Of A 3-sphere = dV/dr = 4(pi)r^2.

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A_Red_Barrow_Herring
1-phenyl-2-(aminoethyl)-propane

'Even Bad Pizza Is Pretty Good.'

N-hydroxy-1-phenyl-2-(ethylamino)-propane.png


IDA_DEBORAH_JONES_PENNINGTON_84
N-hydroxy-1-phenyl-2-(ethylamino)-propane

(Not That I'm Saying She Has And/Or Had Any Kind Of Alcohol Problem AT ALL.)

3-oxo-1-(dimethylamino)-3-(4-(1-oxopropoxy)phenyl)-2-methylpropane.png


QUEEN_NAOMI_CAMPBELL_WILLIAMSII THE ONLY!
3-oxo-1-(dimethylamino)-3-(4-(1-oxopropoxy)phenyl)-2-methylpropane

A Suspected Opioid

Many Hommes Ride With No Soul.
B.I.G.G.I.E

'Shortee Gon Be A Huge O'Boss Hog Wash Me' by 2PAC(Molecule A Name) Shakiro.

HIGH, I AM ANDREW P, BUT YOU CAN JUST CALL ME 'apollo30.' One Of My Dead Bodies Is Buried Underneath The Old Masquerade In Atlanta. How Touching!



A KID Is A Young Goat.
Goats Will Eat Almost ANYTHING Just To Get HIGH.
 
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It's Just

1,4-bis(2-(3,4-methylenedioxyphenyl)-1-methylethyl)-piperazine.png


TWO_DOPE_BOYZ_IN_A_CADILLAC
1,4-bis(2-(3,4-methylenedioxyphenyl)-1-methylethyl)-piperazine

1-(2-(3,4-methylenedioxyphenyl)-1-methylethyl)-3-(2-phenyl-1-methylethyl)-5-(2-(3,4,5-trimethoxyphenyl)-1-methylethyl)-1,3,5-triazacyclohexane.png


YAHWEH
1-(2-(3,4-methylenedioxyphenyl)-1-methylethyl)-3-(2-phenyl-1-methylethyl)-5-(2-(3,4,5-trimethoxyphenyl)-1-methylethyl)-1,3,5-triazacyclohexane

1-(2-(3,4-methylenedioxyphenyl)-1-methylethyl)-4-(2-phenyl-1-methylethyl)-piperazine.png


CRACKALACKIAN
1-(2-(3,4-methylenedioxyphenyl)-1-methylethyl)-4-(2-phenyl-1-methylethyl)-piperazine

1-(1-methyl-2-(3,4-methylenedioxy-5-methoxyphenyl)ethyl)-4-(2-(indole-3-yl)ethyl)piperazine.png


THE_HOLY_GHOST
1-(1-methyl-2-(3,4-methylenedioxy-5-methoxyphenyl)ethyl)-4-(2-(indole-3-yl)ethyl)piperazine
 
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Finally, a way to get a neuropeptide S agonist through the blood-brain barrier:


Self-assembling modified neuropeptide S enhances nose-to-brain penetration and exerts a prolonged anxiolytic-like effect

Abstract​


Anxiety disorders are the most common mental diseases and can greatly disrupt everyday life. Although there has been substantial research on anxiety disorders, novel therapeutics are needed. Neuropeptide S (NPS) is a potential therapeutic candidate owing to its strong anxiolytic activity; however, some disadvantages, such as its poor metabolic stability and inability to cross the blood–brain barrier (BBB), limit its use in the clinic. Herein, inspired by nose-to-brain drug delivery strategies, an endogenous 20-amino-acid-long mNPS peptide was modified by incorporating palmitic acid into its functional Lys12 side chain (M-3), which was expected to facilitate nose-to-brain penetration and exert a prolonged anxiolytic-like effect compared to mNPS. We found that M-3 assembled into nanofibers that retained the bioactivity of NPS and exhibited obvious improvements in metabolic stability. Notably, as expected, self-assembled M-3 was able to penetrate into the brain and exert anxiolytic effects. The elevated plus-maze (EPM) results further revealed that M-3 could produce prolonged anxiolytic-like effects in mice. In vivo imaging studies revealed that self-assembled M-3 could be efficiently transported from the nasal cavity to the brain. Furthermore, when intranasally administered, this molecule exhibited a significantly prolonged anxiolytic-like effect, which further illustrated that this molecule has a potent nose-to-brain penetration in vivo. Overall, this self-assembled nanofiber showed potent nose-to-brain penetration ability and prolonged bioactivity.
 
1-(2,4,6-trimethoxyphenyl)-1-carbomethoxy-1-(2-piperidinyl)methane.png


JIGGAPROJEWGYPSU (aka DREWSKI)
1-(2,4,6-trimethoxyphenyl)-1-carbomethoxy-1-(2-piperidinyl)methane

1-(4-(propylthio)-2,5-dimethoxyphenyl)-1-carbomethoxy-1-(2-piperidinyl)methane.png


JASPERJEWSERZIT (aka TACOCAT)
1-(4-(propylthio)-2,5-dimethoxyphenyl)-1-carbomethoxy-1-(2-piperidinyl)methane
 
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1-(2-methylphenyl)-2-aminopropane.png


PHEN
1-(2-methylphenyl)-2-aminopropane

1-(2-methylphenyl)-1-(carbomethoxy)-1-(2-piperidinyl)methane.png


AGINS
1-(2-methylphenyl)-1-(carbomethoxy)-1-(2-piperidinyl)methane

CH3-O-CH3 (g)

WAKE
methyl methyl ether

1-(2-pyridinyl)-1-(2-methylphenyl)methyl%20diethylaminoethyl%20ether.png


JAMES_JOYCE
1-(2-pyridinyl)-1-(2-methylphenyl)methyl diethylaminoethyl ether

-inspired by orphenadrine
-speaking of orphans, it turns out I may be one until and unless the rest zof my so called family gets their DNA tested :/

1-(3,4-methylenedioxyphenyl)-1-(2-piperidinyl)-1-(2-methylphenyl)methane.png


KRE_8_IV
1-(3,4-methylenedioxyphenyl)-1-(2-piperidinyl)-1-(2-methylphenyl)methane

That Name Looks Like Something You Might Find On A License Plate.

1,1,1-tri(phenyl)-1-(2-piperidinyl)-methane.png


CLUSTER_FUCK
1,1,1-tri(phenyl)-1-(2-piperidinyl)-methane

Pardon My French. It Isn't Tres Bien.

1-carbomethoxy-1-(2-piperidinyl)-1-(6-methoxyindole-3-yl)methane.png


PIENSO_PENSEES
1-carbomethoxy-1-(2-piperidinyl)-1-(6-methoxyindole-3-yl)methane

Cogito, Ergo Zoom.

Apres Moi, Le Deluge.
 
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1-oxo-1-(2-piperidinyl)-1-(4-fluoro1-pentylindole-3-yl)methane.png


TACOCATRACECARRACECARTACOCAT
1-oxo-1-(2-piperidinyl)-1-(4-fluoro1-pentylindole-3-yl)methane

"Nobody Likes Fluorine."--Professor Penland, Georgia Southern University.

There Is A Time And A Place For Everything Under Heaven.

Madam, I Made Adam.

 
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piperidinyl ketones taste just like normal cathinones (pentedrone, hexedrone) but are equally morish and jittery as the pyrrolidines.
 
piperidinyl ketones taste just like normal cathinones (pentedrone, hexedrone) but are equally morish and jittery as the pyrrolidines.
Interesting. Can you (or anyone, really) tell me anything about the psychoactive or lack thereof of the following compound:

N-((2-methoxyphenyl)methyl)-1-phenyl-2-aminopropane.png


CARRE_VIEUX
N-((2-methoxyphenyl)methyl)-1-phenyl-2-aminopropane

It is basically just N-(2-MeO)Bz-amphetamine.
 
3MeO-N-2-Methoxybenzylphenethylamine turned up recently but i know nothing about its pharmacology or that of your compound.
 
N,N-diethylaminocarbonyl-2,6-dimethoxy-4-(2-amino-2-methylethyl)benzene.png


MEOW
N,N-diethylaminocarbonyl-2,6-dimethoxy-4-(2-amino-2-methylethyl)benzene

N,N-diethylaminocarbonyl-2,5-dimethoxy-4-(2-amino-2-methylethyl)benzene.png


WOOF!
N,N-diethylaminocarbonyl-2,5-dimethoxy-4-(2-amino-2-methylethyl)benzene

N,N-diethylaminocarbonyl-4-(2-amino-2-methylethyl)benzene.png


GRRR
N,N-diethylaminocarbonyl-4-(2-amino-2-methylethyl)benzene

N,N-diethylaminocarbonylbenzene.png


WHOOPI
N,N-diethylaminocarbonylbenzene

N,N-diethylaminocarbonyl-3,4-methylenedioxybenzene.png


GOLDBERG
N,N-diethylaminocarbonyl-3,4-methylenedioxybenzene

For All I Know, These Don't Do Jack. But, Like I Said, I Don't Know. Ich Weiss Nichts.

1-pentyl3-(N,N-diethylaminocarbonyl)indole.png


THE_RIDDLER
1-pentyl-3-(N,N-diethylaminocarbonyl)indole
 
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THE_WIDDLER
1-phenyl-1-(N,N-diethylaminocarbonyl)-1-(2-piperidinyl)methane

1-phenyl-1-(N,N-dimethylaminocarbonyl)-1-(2-piperidinyl)methane.png


THE_TWIDDLER
1-phenyl-1-(N,N-dimethylaminocarbonyl)-1-(2-piperidinyl)methane

1-phenyl-1-(aminocarbonyl)-1-(2-piperidinyl)methane.png


THE_FIDDLER
1-phenyl-1-(aminocarbonyl)-1-(2-piperidinyl)methane

1-(3-pyridinyl)-1-(1-pyrrolidinyl)methanone.png


NIC_FIT
1-(3-pyridinyl)-1-(1-pyrrolidinyl)methanone
 
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STIMSTIM
1-(2-methylphenyl)-1-oxo-2-methylaminopropane

4-(2-methyl-2-aminoethyl)-2,5-dimethoxybenzaldehyde.png


BRITNEY SPEARS
4-(2-methyl-2-aminoethyl)-2,5-dimethoxybenzaldehyde

I See You. And I Just Want To Dance With You.

4-(2-methyl-2-aminoethyl)-benzaldehyde.png


SUSAN B. ANTHONY
4-(2-methyl-2-aminoethyl)-benzaldehyde

The B. Stands For BROWNELL.

1-(4-(1-oxomethyl)indole-3-yl)-2-dimethylaminoethane.png


THE_HARRY_S_TRUMAN_SHOW
1-(4-(1-oxomethyl)indole-3-yl)-2-dimethylaminoethane

Need to protect a carbonyl functional group? Try ethylene glycol!

HO-CH2CH2-OH
ethylene gylcol

Need to deprotect?
Add H+.

4-(2-methyl-2-aminoethyl)-2,6-dimethoxybenzaldehyde.png


FIONA_APFEL
4-(2-methyl-2-aminoethyl)-2,6-dimethoxybenzaldehyde
 
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