The combination of piracetam (various racetams) and alcohol: discussion

[DexterMeth]

I wanted to foremost know if piracetam potentiates ethenol, but then many factors come into play as I THINK I'm starting to understand.

A simply yes answer is far from sufficient.

Is this combo very dangerous?
Is this combo, not so if you drink less?

I've noticed I slur less and don't need as much alcohol (well, I remain coherant and don't stumble and actually hardly feel drunk yet obviously am), and the day after, if I did NOT dose piracetam the day/night I was drinking, it essentially removes the hangover entirely.


I apologize in advance for the OD/BDD quality of a thread starter, but I can edit it in the AM.

I googled this crap for hours and realized Bluelight needs to have the real deal on this, and trail "off" onto many of other factors, because well; we are the shit.

(I will edit soon enough)

So.. for starters: does piracetam potentiate alcohol?

 

[Swimmingdancer]

From what I have read, piracetam likely doesn't potentiate alcohol but reduces some of the side effects.

But an opinion poll I saw on another drug forum had the following results:
Piracetam potentiates the effects of alcohol - 48.60%
Piracetam diminishes the effects of alcohol - 13.64%
No different than alcohol alone - 12.59%
other - 25.17%

However, I haven't yet seen any studies that found that piracetam potentiates alcohol. I did read a theory somewhere that alcohol might perhaps slightly synergize with piracetam or potentiate piracetam.

Here is an animal study that found piracetam did not potentiate alcohol (granted they can't really tell how the mice were feeling inside though, just how they behaved):

Piracetam reduced the intensity of withdrawal behavior in mice that had been exposed to ethanol for 4 days. However, in contrast to other antiwithdrawal agents, piracetam did not potentiate the sedative effects of acute ethanol administration. While the mechanism of action of piracetam is unknown, these findings suggest that piracetam elicits its antiwithdrawal effects by a mechanism differing from that of other agents.[Source]

There are a bunch of studies in both humans and animals that found that piracetam can reduce the side effects of alcoholism and withdrawing from alcohol.

 

[nAON]

Somewhat anecdotal and a bit of a generalisation, but from what I heard, the -racetams tend to potentiate stimulants while have little or even a detrimental effect on downers. But as SD said, it seems to decrease side effects in a very wide range of drugs.

 

[DexterMeth]

I've found it often makes me end up consuming MORE alcohol than usual, because of the perceived effects of being less drunk when in fact I'm easily just as if not more.

It definitely significantly kills a large portion of effects of NMDA antagonizing dissociatives, such as DXM/ketamine/MXE/PCP ..not sure about nitrous oxide. I'm getting off subject though. I guess alcohol is too non-specific in action?

I really do not know.