Here's the final and most refined Esoteric, Alchemical, and Shamanic Ranking of Psychoactive Substances.
True mastery is not in consuming the fire or the void, but in standing between them, unshaken.
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Source (has many more esoteric musings)
The Alchemy of Psychoactive Substances: A Yin-Yang, Elemental, and Esoteric Ranking
(Omnicyclion.org Insight Edition)
Caution: The Path of Fire and the Abyss
The alchemist does not seek escape but understanding. The shaman does not seek self-destruction but connection.
True mastery is not in consuming the fire or the void, but in standing between them, unshaken.
The Final Top-20 Ranking of Psychoactive Substances
(From Most Yang to Most Yin, Across Multiple Esoteric Traditions)
| Rank | Substance | Yin-Yang Balance | Hindu Chakra | Hermetic Alchemy | TCM (Traditional Chinese Medicine) | Ayurveda | African Traditional Spirituality (ATS) |
|---|---|---|---|---|---|---|---|
| 1 | Methamphetamine & Cocaine (Hard Stimulants) | Most Yang – Hyper-Aggressive Willpower | Manipura (Solar Plexus, Pure Will) | Red Sulfur (Mars, Aggressive Fire) | Extreme Yang – Fire Excess | Pitta Dominant (Overheated, Destructive) | Shango Energy (Lightning, Raw Power, Unstable Fire)   |
| 2 | Nicotine | Extreme Yang – Focused, Cutting Clarity | Ajna (Third Eye, Sharp Mental Focus) | Air Sulfur (Mercury, Trickster Focus) | Dry Fire – Metal Element Activation | Pitta & Vata (Quick & Cold Fire) | Eshu Energy (Cunning, Trickster Clarity, The Crossroads)  |
| 3 | Ibogaine | Highly Yang – Rooted Warrior Clarity | Muladhara (Root, Survival Instincts) | Saturnian Sulfur (Ruthless Self-Review) | Yang Earth – Deep Root Energy | Kapha-Pitta (Grounded but Intense) | Ancestral Channeling, Bwiti Medicine (Reveals Destiny & Past Wrongs)   |
| 4 | San Pedro (Mescaline Cactus) | Highly Yang – Solar Warrior Strength | Anahata (Heart, Solar Strength) | Solar Gold (Masculine Light, Spiritual Fire) | Warm Yang – Harmonizing Energy | Balanced Pitta-Kapha (Healer-Warrior Blend) | Ogún Energy (Strength, Expansion, Warrior’s Path)   |
| 5 | Memantine | Yang with Saturnian Mental Stability | Ajna (Third Eye, Logical Clarity) | Air Mercury (Cold Cognitive Fire) | Balanced Yang – Stabilizing Qi | Vata-Pitta (Structured & Cold) | Oshosi Energy (Precision, Disciplined Thought, Silent Hunter Mind)   |
| 6 | LSD | Balanced but Yang-Leaning – Electric Expansion | Ajna & Sahasrara (Crown, Cosmic Illumination) | Electric Mercury (Mind Expansion, Illumination) | Yang Metal – Cutting Perception | Pitta-Vata (Quick Mind, Fire & Air Mix) | Orunmila Energy (Divine Wisdom, Knowledge Streams, Cosmic Sight)  |
| 7 | Caffeine & Theobromine | Yang but More Balanced – Gentle, Warm Clarity | Manipura (Solar Energy & Endurance) | Gentle Sulfur (Controlled Fire, Stability) | Mild Yang – Stimulant without Overheat | Balanced Pitta (Energizing but Not Overwhelming) | Oya Energy (Speed, Alertness, Stormy Energy)   |
| 8 | 2C-B & 2C-E (Simple Phenethylamines) | Balanced – Mind-Body Alchemy | Svadhisthana (Sexual & Creative Flow) | Venusian Sulfur (Beauty, Artistic Activation) | Balanced Fire & Water – Qi Harmonization | Sattvic Pitta-Vata (Passion & Creativity) | Osun Energy (Sensory Beauty, Art, Sexuality, Water Flow)   |
| 9 | MDMA | Slightly Yang – Heart-Focused Warm Expansion | Anahata (Love & Emotional Opening) | Solar Venus (Empathy, Expansion) | Warm Qi – Joyful Fire Activation | Balanced Pitta (Emotional & Warm-Hearted) | Yemaya Energy (Deep Love, Ocean’s Embrace, Healing Waters)  |
| 10 | Methoxetamine (MXE) | Balanced – Fluid Yet Structured Dissociation | Ajna & Sahasrara (Third Eye & Crown Access) | Mercurial Neptune (Fluid Thought Expansion) | Balanced Yin-Yang – Mystical But Grounded | Vata-Pitta (Fluid but Sharp Cognition) | Olokun Energy (Deep Mystical Waters, Ocean Depths of Consciousness)  |
| 20 | Salvia Divinorum | Most Yin – Fractal Ego-Death & Total Disintegration | Da'at (Beyond the Tree – Chaos & The Abyss) | Saturnian Chaos (Total Fractal Breakdown) | Extreme Yin – Dissolving Self into Nothingness | Deep Kapha (Total Surrender to the Unknown) | Oya’s Darkest Form (Storm of Pure Oblivion, Gateway to the Unknown)  |
Final Insights Across Esoteric Traditions
- Hindu Chakras: The most Yang substances activate Manipura (Solar Willpower) and Ajna (Mind Focus), while Yin substances activate Sahasrara (Cosmic Dissolution) or Da’at (Abyssal Oblivion).
- Hermetic Alchemy: The Yang substances belong to Sulfur and Mercury (Fiery Drive & Mental Sharpness), while Yin substances are linked to Saturn, Water, and Chaos (Dissolution & Forgetting).
- Traditional Chinese Medicine (TCM): Yang substances activate Qi & Fire, while Yin substances dissolve Qi, grounding or dissolving perception.
- Ayurveda: Pitta-driven substances are Yang (Heat, Fire, Aggression), while Kapha & deep Vata substances are Yin (Dissolution, Dreaming, Darkness).
- African Traditional Spirituality (ATS): Each Orisha corresponds to an energy pattern, from Shango’s Lightning Fire (Meth) to Oya’s Pure Oblivion (Salvia).
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Source (has many more esoteric musings)
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