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THC biosynthesis vs chemical synthesis

So nicotine and THC are humans' blessed gifts, while they're natures' enemies?

That's awesome.
 
we'll see when it starts shipping - trying to get a business model together... anyone know a venture capitalist with an edgy attitude? :)
 
mmackie908 = pretty much - THC is one hella badass chemical... think uber detergent of the future :)
 
THC's properties and synthesis pathway are nobody's property but cannabis' for all of us to use.

Intellectual property on biological processes makes me sick.
 
That's a great question - and here's the size of it - it depends... there are numerous strains of e coli.... while THC is deadly to some strains it is neutral to positive with others.... e. coli, tobacco, and many other organisms provide awesome vector properties for THC - and there are also fungi that are attacked by THC while others thrive...
 
yeah

Hi Nibiru - I tend to agree with you... it's rather silly ain't it... of course that's why you should read the story of this "discovery" - we continually laugh about it... the fast answer is - that is absolutely correct... any more than any patent or law based on atomic influence on neuronal activity is silly in the extreme.... see here - we didn't make the rules, we're doing our best to work with the system.. and it ain't been easy.

Ultimately one of the main reasons we are going with the USPTO as a means of publication is to ensure a stable public record. The USPTO database gives open access to everyone on earth - thus all of the notes and references on generating THC enzymatically are now openly available to you to test at home for personal use. The only restriction a patent creates is on commercialization... so to all of you who are skilled in the arts of genetics as well as legally able to possess THC you are strongly encouraged to read the patent and do the work for yourselves :)
 
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greenstoner said:
That's a great question - and here's the size of it - it depends... there are numerous strains of e coli.... while THC is deadly to some strains it is neutral to positive with others.... e. coli, tobacco, and many other organisms provide awesome vector properties for THC - and there are also fungi that are attacked by THC while others thrive...
Click to expand...

Ok, so what exactly is the mechanism by which it exerts it's bacteriocidal effects?
 
Ylide - it predominantly works against gram positive bacteria - here's a decent reference to learn more
http://www.springerlink.com/content/x258t54uq5012r1w/

In short it binds against the cell membrane and destabilizes the critter... while the exact molecular mechanism isn't entirely clear, it is safe to guess that its lypophilic properties have something to do with it..
 
Pathway to legal THC

I have been dreaming of this for a while, but I do not have the background in plant molecular genetics to pull it off. But my thought was, if you have a transgenic vector for THC biosynthesis, how hard would it be to transfer it to a common household plant such as Kentucky Blue grass or Fescue? With billions of acres of the stuff growing across the country Law Enforcement would be face with only two choices, either legalize THC or outlaw turf grass. Either option would be fine with me.
 
that's the idea...

yeah, dandelions are particularly suited for genetic engineering....
 
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