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Opioids Taking naloxone while on bupe to feel high on opiates

aesthetic.addict

aesthetic.addict

Bluelighter
Joined
Apr 5, 2025
Messages
100
Would it work to take a low dose of naloxone while on 7 mg bupe daily, like induse withdrawals, to be able to feel the effects of oxycontin?
Taking the quick route instead of doing a tedious taper... of course with the oxys already procured so that I can take it a while after.
Also how long would I have to wait after the naloxone (nasal spray) to take the oxys?
And would it work if you're on the subutex 300mg shot? Since the bupe is continuously released.
(I already know I shouldn't do this, please spare me the comments about that🙏)
 
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Nope
you wont get high from high dose bupe
when you get your dose lower (which isnt hard btw)
you'll get less sedativeness and more of a oxy like high

this is my suggestion to you , and you might not like the idea, but with bupe less is more
i suggest that you take a 2mg and split it into 4 pieces. put 2 of the pieces on both side of your mouth. wait a full 30 minutes for that 1mg to dissolve. then take the next 2. you shouldnt need more than the 2mg and you'll be way higher than your 7-8mg normal dose. if not, take another 1mg. then another 1mg.
i promise you dont need high doses of bupe to achieve the effect you're looking for
the only thing high doses of bupe are good for is to kill cravings and to keep people off other opiates by blocking the effect because bupe binds so hard to the receptors


also do not use caffeine or benzos or any other sedative at the same time it will negate the effects
and no, potentiators wont do anything for your high dose of bupe

bupe for pain is given in the 100mcg to 1000mcg (1mg) range because its actually extremely strong. most people do not realize how strong it actually is.
 
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also if you're on the shot you're just limiting yourself from lowering your dose, kinda pointless really, but up to you
 
ryax said:
Nope
you wont get high from high dose bupe
when you get your dose lower (which isnt hard btw)
you'll get less sedativeness and more of a oxy like high

this is my suggestion to you , and you might not like the idea, but with bupe less is more
i suggest that you take a 2mg and split it into 4 pieces. put 2 of the pieces on both side of your mouth. wait a full 30 minutes for that 1mg to dissolve. then take the next 2. you shouldnt need more than the 2mg and you'll be way higher than your 7-8mg normal dose. if not, take another 1mg. then another 1mg.
i promise you dont need high doses of bupe to achieve the effect you're looking for
the only thing high doses of bupe are good for is to kill cravings and to keep people off other opiates by blocking the effect because bupe binds so hard to the receptors


also do not use caffeine or benzos or any other sedative at the same time it will negate the effects
and no, potentiators wont do anything for your high dose of bupe

bupe for pain is given in the 100mcg to 1000mcg (1mg) range because its actually extremely strong. most people do not realize how strong it actually is.
Click to expand...
But I'm not trying to get high on buprenorphine, I wondered if you can use naloxone to get the bupe out of your system and then take oxycontin (I want to get high on oxys not the bupe)
 
aesthetic.addict said:
But I'm not trying to get high on buprenorphine, I wondered if you can use naloxone to get the bupe out of your system and then take oxycontin (I want to get high on oxys not the bupe)
Click to expand...
oh, im not sure. i dont think it takes away tolerance otherwise addicts would just overdose over and over again from their tolerance being lowered everytime they're narcanned
 
LSDiesel said:
No the naloxone actually doesn’t knock off buperenorphine and if it does it only does it temporarily as buperenorphine has higher binding affinity than naloxone and outcompetes it for Mu receptor sites
Click to expand...
Oh okay, I thought I had a great revelation but seems like I was in the wrong 😭 a taper it is then. I'm tapering either way so.
Would you feel anything on oxys if you go down to 4mg buprenorphine/day and then take 24hours without a bupe dose before taking the oxys?
 
aesthetic.addict said:
Oh okay, I thought I had a great revelation but seems like I was in the wrong 😭 a taper it is then. I'm tapering either way so.
Would you feel anything on oxys if you go down to 4mg buprenorphine/day and then take 24hours without a bupe dose before taking the oxys?
Click to expand...
You really need to wait 48-72hrs minimum for bupe's receptor occupancy to go down enough in order to feel the oxy, especially in higher doses.

Maybe just wait. Ask yourself, is it even worth it? It always sucks ruining your sobriety for a high you won't even feel.
 
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