BitterSweetBalance
Greenlighter
- Joined
- Mar 12, 2014
- Messages
- 1
I have read so many posts about this issue which generally ask, "what is the best route of administration to get the optimal effect, most strength, longest duration, or greatest bioavailability of amphetamine." swim has had extensive experience with dexamphetamine in particular, but amphetamines in all categories seem to have extremely similar pharmacology from my research.
I had taken dexamphetamine for almost a decade, but it took several years before swim started actually getting the overall effect from it that swim desired. When swim first started the medication and found that taking it orally was disappointing and basically ineffective after only a few days,swim began snorting it and never stopped taking that route for about three or four years because swim repeatedly searched for the best route of administration, and based on what swim read in the past, it seemed that snorting (insuffulation or nasal route) administration was "SUPPOSED" to be the best in terms of Bioavailability.
Snorting dex produces very short duration of effects and for some reason it creates a massive tolerance very quickly. swim found that snorting would be "good" in massive amounts over two or three days, but his prescription consistently ran out extremely early every month without fail but swim was so stubborn regarding his belief that snorting was the best and only way to get the most out of it. swim could not justify altering his regime for years even though it was clearly harming him. swim got throat infections, mouth ulcers, the magnesium stearate in the pills is corrosive to the lungs which affected his breathing, the crashes were extreme and induced ridiculous debilitating depression and lethargy, the days were long in between prescription refills,swim craved and fiend other drugs like marijuana and alcohol and tobacco and ecstasy to combat the come-down, and even the high itself was very anxious/edgy/unstable/uncomfortable at times.
I knew that that the medication was undeniably necessary for his success, butswimneeded to find a way to make it effective and consistent and work every single day in the long-long term, or else swim would have to suffer the consequences of going off of the med and face his frustrating and debilitating ADD symptoms. These symptoms made swim upset and even suicidal due to the lack of production and interest in life that they induced. swim specifically could not focus on producing, playing, recording, or even enjoying the creative and original music swim loved so much, but ADD medication also made swim more social and motivated in general to do regular activities and work at a job.
swim FINALLY found the way to achieve his goal regarding dexamphetamine.
1) The obvious first thing to address was taking the medication in a consistent and uniform manner each day every day. To do so swim got help at first from a family member who distributed his daily dose to him each day so that swim could not go over.
2) The next issue was the route of administration. Oral administration is undeniably weak for him, even at the maximum dose of 60mg/day. swim was not satisfied with taking it orally when swim was used to such intensity and strength whenswimused to snort it, so swim did more research and found that there may be another alternative: Sublingual.
Sublingual administration (crushing the powder and letting it dissolve UNDER your tongue) is another way for the drug to access the thin, absorbent, close-to-the surface, mucous membranes that you can also access through the nose or the rectum. It was found by some that this route's biovailabilty rivalled and even exceeded the apparent bioavailability of the nasal route (75%+?). Sublingual admin. also provide a much more steady, and much longer-lasting effect. Surprisingly swim had never given sublingual a try and had just skipped straight to nasal ingestion. Ultimately swim was very pleased with sublingual ingestion. His dose lasted so long every day that swim had no complaints any more. 60mgs/day was enough and it worked every single day since swim began. Also, the comedown was very soft and gentle compared to snorting it.
Currently i take the following daily:
- several spaced out spoonfuls of sodium bicarbonate to poetentiate the amphetamine (this is well- known and is even listed as an interaction on the pharamacist's information sheet for dexamphetamine prescriptions)
- a relatively SMALL amount of caffeine in the morning -which has been found to help with ADD over just the medication alone.
- bupropion (for depression), BUT it ALSO greatly potentiates and lengthens the effects of dopamine-increasing drugs like amphetamines.
- baclofen (for alcoholism), but it also has a nice relaxing effect on ay edginess that one may normally feel throughout a dexamphetamine-effected day
this is his basic daily schedule:
morning -tea or coffee (100-200 mg worth, any more will be harmful to your dexamphetamine experience)
morning -spoonful of sodium bicarbonate (baking soda)
morning -300 mg bupropion crushed-oral
morning -15 mg dexamphetamine crushed sublingual
midday -spoonful of sodium bicarbonate
midday -15 mg dexamphetamine crushed -sublingual
midday -125mg baclofen crushed -oral (it takes about 2-4 hours to kick in btw)
afternoon -spoonful of sodium bicarbonate
afternoon -30 mg dexamphetamine crushed -sublingual
I has found this regime to be very consistent and so utterly satisfying that wishes I could have started it sooner in his life, but is glad, at least, that swim eventually found it and it works.
swim wants to share with those who are either have problems with their tolerance to dexamphetamine, or the duration of its effectiveness, or those who are specifically bent the nasal route of administration and can't seem to make the medicine actually work properly on a daily basis over the long-term, or in an overall effective and non-guilty/unhealthy manner, as swim has faced all of these problems before.
Snorting, it seems, does not have the Bioavailability of the figures which are posted around the internet. It may be because the some of the powder is wasted in non-absorbant parts of the nose such as hairs or non-absorbant skin, or caught up in mucous and therefore never 'activated,' or because some, perhaps lots, of the powder is swallowed and orally digested anyways via the inevitable 'drip'. The duration for snorting is very short and the intensity of the addiction and desire to repeat the action with the nasal route is almost uncontrollably intense. swim would be very, very surprised if anyone found that they could snort it and maintain a regular regime/ sustainable habit/ healthy or consistent lifestyle. I simply doesn't think that it is possible.
hope this helps someone some day.
I had taken dexamphetamine for almost a decade, but it took several years before swim started actually getting the overall effect from it that swim desired. When swim first started the medication and found that taking it orally was disappointing and basically ineffective after only a few days,swim began snorting it and never stopped taking that route for about three or four years because swim repeatedly searched for the best route of administration, and based on what swim read in the past, it seemed that snorting (insuffulation or nasal route) administration was "SUPPOSED" to be the best in terms of Bioavailability.
Snorting dex produces very short duration of effects and for some reason it creates a massive tolerance very quickly. swim found that snorting would be "good" in massive amounts over two or three days, but his prescription consistently ran out extremely early every month without fail but swim was so stubborn regarding his belief that snorting was the best and only way to get the most out of it. swim could not justify altering his regime for years even though it was clearly harming him. swim got throat infections, mouth ulcers, the magnesium stearate in the pills is corrosive to the lungs which affected his breathing, the crashes were extreme and induced ridiculous debilitating depression and lethargy, the days were long in between prescription refills,swim craved and fiend other drugs like marijuana and alcohol and tobacco and ecstasy to combat the come-down, and even the high itself was very anxious/edgy/unstable/uncomfortable at times.
I knew that that the medication was undeniably necessary for his success, butswimneeded to find a way to make it effective and consistent and work every single day in the long-long term, or else swim would have to suffer the consequences of going off of the med and face his frustrating and debilitating ADD symptoms. These symptoms made swim upset and even suicidal due to the lack of production and interest in life that they induced. swim specifically could not focus on producing, playing, recording, or even enjoying the creative and original music swim loved so much, but ADD medication also made swim more social and motivated in general to do regular activities and work at a job.
swim FINALLY found the way to achieve his goal regarding dexamphetamine.
1) The obvious first thing to address was taking the medication in a consistent and uniform manner each day every day. To do so swim got help at first from a family member who distributed his daily dose to him each day so that swim could not go over.
2) The next issue was the route of administration. Oral administration is undeniably weak for him, even at the maximum dose of 60mg/day. swim was not satisfied with taking it orally when swim was used to such intensity and strength whenswimused to snort it, so swim did more research and found that there may be another alternative: Sublingual.
Sublingual administration (crushing the powder and letting it dissolve UNDER your tongue) is another way for the drug to access the thin, absorbent, close-to-the surface, mucous membranes that you can also access through the nose or the rectum. It was found by some that this route's biovailabilty rivalled and even exceeded the apparent bioavailability of the nasal route (75%+?). Sublingual admin. also provide a much more steady, and much longer-lasting effect. Surprisingly swim had never given sublingual a try and had just skipped straight to nasal ingestion. Ultimately swim was very pleased with sublingual ingestion. His dose lasted so long every day that swim had no complaints any more. 60mgs/day was enough and it worked every single day since swim began. Also, the comedown was very soft and gentle compared to snorting it.
Currently i take the following daily:
- several spaced out spoonfuls of sodium bicarbonate to poetentiate the amphetamine (this is well- known and is even listed as an interaction on the pharamacist's information sheet for dexamphetamine prescriptions)
- a relatively SMALL amount of caffeine in the morning -which has been found to help with ADD over just the medication alone.
- bupropion (for depression), BUT it ALSO greatly potentiates and lengthens the effects of dopamine-increasing drugs like amphetamines.
- baclofen (for alcoholism), but it also has a nice relaxing effect on ay edginess that one may normally feel throughout a dexamphetamine-effected day
this is his basic daily schedule:
morning -tea or coffee (100-200 mg worth, any more will be harmful to your dexamphetamine experience)
morning -spoonful of sodium bicarbonate (baking soda)
morning -300 mg bupropion crushed-oral
morning -15 mg dexamphetamine crushed sublingual
midday -spoonful of sodium bicarbonate
midday -15 mg dexamphetamine crushed -sublingual
midday -125mg baclofen crushed -oral (it takes about 2-4 hours to kick in btw)
afternoon -spoonful of sodium bicarbonate
afternoon -30 mg dexamphetamine crushed -sublingual
I has found this regime to be very consistent and so utterly satisfying that wishes I could have started it sooner in his life, but is glad, at least, that swim eventually found it and it works.
swim wants to share with those who are either have problems with their tolerance to dexamphetamine, or the duration of its effectiveness, or those who are specifically bent the nasal route of administration and can't seem to make the medicine actually work properly on a daily basis over the long-term, or in an overall effective and non-guilty/unhealthy manner, as swim has faced all of these problems before.
Snorting, it seems, does not have the Bioavailability of the figures which are posted around the internet. It may be because the some of the powder is wasted in non-absorbant parts of the nose such as hairs or non-absorbant skin, or caught up in mucous and therefore never 'activated,' or because some, perhaps lots, of the powder is swallowed and orally digested anyways via the inevitable 'drip'. The duration for snorting is very short and the intensity of the addiction and desire to repeat the action with the nasal route is almost uncontrollably intense. swim would be very, very surprised if anyone found that they could snort it and maintain a regular regime/ sustainable habit/ healthy or consistent lifestyle. I simply doesn't think that it is possible.
hope this helps someone some day.
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