Opioids Stadol Nasal Spray

[Tryptamino]

Ive aquired a bottle of the butorphanol nasal spray, which I intend to mainly use for pain, but first I want to know a few things, since my internet search was not particularly helpful:
Is it recreational? If so, is the high particularly enjoyable, or was it nothing special? Can you compare it to oxycodone?
What is the equipotent dose of nasal butorphanol to 20mg oral oxycodone?
How long does analgesia last?
What else can you tell me about it?

EDIT: I think this might be better suited in BDD, but I figure that people in OD are more knowledgable about less common opioids such as this, as well as pain relief in general.

 

[Hiltoniano]

I cannot answer your questions. I have one to add though: is it in nasal apart for bioavailability reasons or what? It seems like an odd ROA for prescription painkillers ie opiates, if that is what this stuff is. So yea...

 

[BeachBum4u]

I was prescribed that stuff after surgery in 95 and it was little different than anything else I'd ever had. As for the second post, I've only heard of this Stadol in a nasal squirt bottle. I think that's just how it's made but it has been a long time since I lst used it. After I did a few squirts I used to start sweating and I remember wanting to do more. I honestly don't remember what it was like though. It's been too long. Please let me know how it goes, I'm curious. Good Luck!

 

[tokenname]

I cannot answer your questions. I have one to add though: is it in nasal apart for bioavailability reasons or what? It seems like an odd ROA for prescription painkillers ie opiates, if that is what this stuff is. So yea...

i know it has a low oral ba.
also..the stadol ns is rx'd alot for migraine relief..
so not having to wait on a swallowed pill could be part of the reason for that roa, also.

 

[tricomb]

It's in nasal form as token said, because it's indicated as breakthrough medication for migraines you know which can come on really fast and if medication is going to be effective it must be given as soon as pain is felt.

It's not prescribed often, and there have been numerous complaints against it reported by the FDA. The brand name Stadol was discontinued a while ago if I remember correctly. I would be really careful with it, even if that meant avoiding it completely. It's used a lot more in veterinary applications than it is in humans I think.

 

[VerbumVincet]

I was prescribed that stuff after surgery in 95 and it was little different than anything else I'd ever had...

Well said...I agree, butorphanol is in a league of its own. The best description I can give you is that is as close to a 'psychedelic opioid' as anything I've ever tried, and I've tried them all. The closest thing I could compare it to would be Talwin NX (pentazocine/naloxone tablets,) but that's not a very good comparison, to be honest. The only similarity is that both Talwin and Stadol are mixed agonist/antagonists or partial agonists - I don't remember, but it would be worth checking out.

I was prescribed the nasal spray, and I used the whole bottle over the course of one night. I should note that I had an exceedingly high tolerance to opiods, and always have. It was not very euphoric at all, and does not resemble oxycodone or any other pure-agonist opioid in my opinion. In fact, the more I used, the more dysphoric the experience became. As I attempted to drift off to sleep, I started having closed-eye visuals and hearing wierd music, voices and other random noises. I never could get to sleep. Other opioids can cause this phenomenon; it's known as 'Yen sleep.' I've experienced it from morphine and Hycodan syrup. It's not unpleasant, but butorphanol took it to a whole new level. I should add, it didn't cause noticeable respiratory depression or histamine release and the associated itching.
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I just stumbled across this on WP when reading about Matrine, a K-opioid receptor agonist/research chem:

It has long been understood that κ-opioid receptor agonists are dysphoric but dysphoria from κ-opioid receptor agonists has been shown to differ between the sexes. More recent studies have shown the aversive properties in a variety of ways and the κ-opioid receptor has been strongly implicated as an integral neurochemical component of addiction and the remission thereof.

It is now widely accepted that κ-opioid receptor (partial) agonists have dissociative and deliriant effects, as exemplified by salvinorin A. These effects are generally undesirable in medicinal drugs and could have had frightening or disturbing effects in the tested humans. It is thought that the hallucinogenic effects of drugs such as butorphanol, nalbuphine, and pentazocine serve to limit their opiate abuse potential.

 

[Captain.Heroin]

It's not prescribed often, and there have been numerous complaints against it reported by the FDA.

Is there a general complaint, or a wide variety of them? Or is that something you cannot find out?

If it's due to the kappa-opioid receptor agonism, I'd venture a guess and say some people are going to be more tolerant of it than others.

 

[izzy66]

I had a bottle about 15 years ago and had a really awful experience with it. Did a few blasts up each nostril, promptly went to sleep for a few hours and then woke up in tears, depressed, in a horrible mood. First and only drug I ever threw in the trash.
I've no explanation for why i reacted the way i did but never tried it again. Made my headache much worse, if anything, but sometimes things work a little sideways on me.
I didn't find anything recreational about it at all.
Best of luck
-izzy

 

[tokenname]

Is there a general complaint, or a wide variety of them? Or is that something you cannot find out?

If it's due to the kappa-opioid receptor agonism, I'd venture a guess and say some people are going to be more tolerant of it than others.

i read that women respond better to it's analgesic affect than men do.
i dunno..maybe that was only interesting to me..