Benzos Speeding elimination of benzos

[madvillain]

I have read that smoking cigarettes causes benzos to be more rapidly eliminated from the body. Could someone explain to me why this is and if there is anything else that can be done to achieve a similar effect? My question has nothing to do with drug testing, I am merely interested in speeding the elimination of my last dose of clonazepam from my body so that I will feel my next dose more strongly. Thanks.

 

[Mr Blonde]

Use The Search Engine.

I'm not sure about clonazepam, but I know with diazepam nicotine causes an increase in the liver enzymes that metabolize the drug. I have not noticed much of an effect when smoking on valium, and since I love to smoke and I love to take valium I continue to do both anyway.

Eliminating the dose from your body won't get that much more out of your next dose if you have a tolerance.

 

[Captain.Heroin]

I don't think speeding up metabolizing clonazepam will eventually potentiate it. I think your benzo tolerance is un-reliant on the clonazepam being in your system - so taking a break is the best way to get better effects out of your clonazepam.

 

[madvillain]

Thanks for the replies. Please forgive me if I'm a bit slow CaptainHeroin, but if benzo tolerance is unreliant on the benzo being in one's system, then why would taking a break reduce tolerance? For background, I only take clonazepam about once a week. I find that if I take it much more frequently than this, I get significantly reduced effects. But this week, there are situations where I have to take it twice in less than a week, so I am interested in speeding the metabolism of the first dose so it feels to my body like I have taken a longer break than I have. Thanks again guys.

 

[thelung]

excersize & drink lots of water I suppose?

 

[Mr Blonde]

Thanks for the replies. Please forgive me if I'm a bit slow CaptainHeroin, but if benzo tolerance is unreliant on the benzo being in one's system, then why would taking a break reduce tolerance? For background, I only take clonazepam about once a week. I find that if I take it much more frequently than this, I get significantly reduced effects. But this week, there are situations where I have to take it twice in less than a week, so I am interested in speeding the metabolism of the first dose so it feels to my body like I have taken a longer break than I have. Thanks again guys.

I think what the ol' Captain was trying to say was similar to what I was saying; that just getting it out of your system won't potentiate it. If you have a tolerance, you have to wait for the receptors to start to down-regulate, which happens once it's completely out of your system and with benzos, if I recall correctly, can take a while for the tolerance to be reduced.

 

[Captain.Heroin]

then why would taking a break reduce tolerance?

Because after a while of continuous use, benzodiazepine receptors will change. After a long break, they may change back.

Also, in my experience, taking a benzo every day for at least a few weeks will quickly lead to tolerance that will only go away after taking a break.

It's not so much tolerance to all effects, but tolerance to the medicinal effects. You may "feel" the effects of the drug, but may still be anxious or awake/not sleepy.

If you are asking about recreational effects, benzos are only good for recreational experiences once in a while; taking a break will help you have another good benzo experience in the future.

For background, I only take clonazepam about once a week. I find that if I take it much more frequently than this, I get significantly reduced effects. But this week, there are situations where I have to take it twice in less than a week, so I am interested in speeding the metabolism of the first dose so it feels to my body like I have taken a longer break than I have. Thanks again guys.

Well really, I think if you have to take it 2x in a week, it should work well both times, especially if your dose of clonazepam is 1mg or lower. That's just what I've experienced, but it can vary from person to person.

Another good idea is to get something else for anxiety, like hydroxyzine, so you can stick to a benzo once a week, and also have another, not as addictive medication, so you can use it more frequently if needed.

 

[madvillain]

Mr. Blonde, thanks for the replies. After reading your post, I did some searching and came across this thread: http://www.bluelight.ru/vb/archive/index.php/t-322299.html
which led me to believe that you must have meant I have to wait for the receptors to be up-regulated in order for tolerance to be reduced.

thelung, I agree exercise helps, don't know why that is.

CaptainHeroin, my use of clonazepam is purely medicinal (for social anxiety) and quite sporadic, in doses of 1-2 mg; sometimes I will go several weeks without taking any. Getting an alternative anxiety medication would have been a good idea for me some time ago, but right now I am trying to finish my last semester of college, and once I am done with that I expect much of my anxiety to go away.

 

[Mr Blonde]

^ God damn it I confused down and up regulating. May God have mercy on my soul!

Yes that is what I was saying. You need to allow your receptors to up-regulate again.

 

[burn out]

if you take clonazpeam once a week, i don't see any reason why speeding it's elimination wouldn't slow down the formation of tolerance.

 

[madvillain]

if you take clonazpeam once a week, i don't see any reason why speeding it's elimination wouldn't slow down the formation of tolerance.

Do you have any idea how to accomplish this burnout?