Some drug discussions. Please get in here. Purpose of receptors

[daveslaine]

Lets assume we were designed by either God or Aliens ok.

What purpose did God or Aliens have when they gave us

Opiate receptor
Serotonin receptors
Dopamine Receptors
Alpha/Beta receptors
Cannabinoid Receptors?

What I mean is, why did they put them there, why did they give us the ability to have different experiences via substances?

Opiate receptors generally provide similar effects no matter what drug, Fentanyl, Darvocet, Hydros, etc.

Dopamine agonists also usually are similar.


Cannabinoids give different effects depending on chemical.

But I think Serotonin is the craziest one. LSD, DMT, 2c-groups, Mescaline, Psilocybin, all provide varying effects completely different, like the widest range of effects for any receptors.

Lets make sense of the reasons srs.

How do they balance each other out anyway? On a daily cycle, we have all of these receptors activated, but how are they helping us grow day by day in order?

I believe opiates help us endure pain, have hope, and keep going.
Dopamine rewards us for our actions, and helps us have the confidence to speak and do things, and enjoy it.. also makes us social.
Serotonin is the happy drug, it makes us satisfied with the moment in our life.
Adrenaline keeps us awake, and alert, and strong.

Am I right? Is this how it is for most or everyone?

Also. There are three psychadelic groups Ive recognized. Can anyone care to explain the differences and which is one is useful for what?

There is cannabis of course, what kind of psychadelic is it and what for?
There is serotonin agonists, what kind are these?
And theres Kappa-opioid agonists, these ones are insane hallucinogens, which kind are these?

 

[slimvictor]

This type of post does not belong here in DiTM.
Please read the guidelines (in my signature) before posting here again.
For now, I will send this on to PS.
(mods, feel free to send on elsewhere if I have misjudged)

 

[rangrz]

Why are we assuming design by a God or alien with no evidence, vs evolution which has evidence?

You also seem unfamiliar with physiology and pharmacology, as you don't seem to acknowledge the physiological, autonomic role of receptors of the types you mentioned, nor their subtypes.

Dopamine receptors react the same to all agonists? Go try some apomorphine and tell me how you feel. Or some aripiprazole.

Serotonin, well... it has a role in coagulation pathway activation too (indeed that is how it got it's name) and excessive blood levels of it can cause disseminated intravascular coagulation... it's not just about seeing pretty colours.

How about non-psychoactive receptor types.
. why don't you care CD8 receptors or their major histocompatibility complex class 1 ligands and how they affect cytotoxic T cell activation?

my point: The concept of a receptor is extremely broad in molecular and cell biology and no defined purpose can be given to the broad concept. Individual receptor classes have assorted functions, most of them pretty "mundane" and in any case, all have a physiological purpose and it's not as simple as you seem to imagine it is.

Go take a molecular biology course and a pharmacology course and come back and tell us if you still think what you expressed in your post.

 

[P A]

I'm not certain where this thread belongs. As rangrz has already indicated, the OP doesn't seem to know what he or she is talking about wrt to biological receptor subtypes. Furthermore, even if proper attention had been paid to the nuances of human neurobiology and psychopharmacology, I'm still unsure what the actual topic might have been. Without further ado, I pronounce this thread closed.