Sleeping pill causes "inappropriate or strange automatic behaviour"

rumpled

Bluelighter
Joined
Nov 1, 2006
Messages
592
2nd Feb 2007

boingboing.net, posted by Mark Frauenfelder

An Australian sleeping pill called Stilnox is suspected of provoking unusual behavior in people.

A suspect sleeping pill is causing Australians to paint the front door, binge-eat, and drive while still asleep, a new study reveals.

The Federal Health Department has received 16 separate reports of odd "sleepwalking" behaviour caused by the drug Stilnox, The Sydney Morning Herald reports.

A woman taking the drug "woke with a paintbrush in her hand after painting the front door while asleep," the Adverse Drug Reactions Advisory Committee said in a bulletin published yesterday.

The health department also received 104 reports of hallucinations and 62 of amnesia relating to the drug.


Reader comment:

Paul says:

Stilnox, the “Australian sleeping pill” (sounds like our Prime Minister) you posted about on Boing Boing, is zolpidem tartrate; the same drug known in the US as Ambien – there have been reports of similar effects in people taking Ambien, as you may be aware.


Link



National Nine News, posted by ninemsn staff

A suspect sleeping pill is causing Australians to paint the front door, binge-eat, and drive while still asleep, a new study reveals.

The Federal Health Department has received 16 separate reports of odd "sleepwalking" behaviour caused by the drug Stilnox, The Sydney Morning Herald reports.

A woman taking the drug "woke with a paintbrush in her hand after painting the front door while asleep," the Adverse Drug Reactions Advisory Committee said in a bulletin published yesterday.

Another patient reportedly gained 23 kilograms over seven months while taking Stilnox.

"It was only when she was discovered eating in front of an open refrigerator while asleep that the problem was resolved," the bulletin said.

The committee also received two alarming reports "which suggest the possibility of driving while asleep."

The new study marks the first time "inappropriate or strange automatic behaviour" related to Stilnox has been noted in Australia since the drug was introduced here in 2000, although cases have been reported overseas.

The health department also received 104 reports of hallucinations and 62 of amnesia relating to the drug.

Alan Brindell, a spokesman for the manufacturer of Stilnox, Sanofi-Aventis, told the Herald it had not been proven that the drug was causing the disturbed sleep behaviour.

Brindell could not provide an estimate for the number of people in Australia using Stilnox, which is only available on prescription and attracts no subsidy.

Link
 
Last edited:
Ive definitely read stuff suggestings Ambien causes sleepwalking and stuff, but damn, painting your front door?

All Ambien does for me is make me insomnia sleep, and make me hate looking at my face in the mirror. Definitely has enough hallucinogenic properties to cause uncomfortable distortions for me.

Interesting read though, thanks :)
 
Yea ambien is some fun/fucked up shit ....I used to do a few shots of vodka followed by 30 - 40mgs Ambien SNORTED. Needless to say the combo made for some bizzare and trippy nights....blackouts from ambien are also very common%)
 
^Jesus dude...I've gone up to 50mg orally, and that was intense, 40mg snorted with vodka would be unreal (even more than usual I mean lol)!

As for these sleeping walking states, it's new to me, I've never experienced it or heard of it before.
 
I took some no-name brand sleeping pill last year.. woke up a couple hours later with every light on in the house... in the hallway. effing sketchy.
 
I'd imagine this could be marketed as a selling point... doing the housework while asleep???

I'd buy it!

I wonder if this is anything to do with the dosage though? Perhaps people taking it on the upper limits of the guidelines?
 
This article missed the funniest side effect:

Two reports suggested patients had driven while asleep, while two described binge-eating and subsequent weight gain.

The tales match another media report last year of a Sydney man who had taken two Stilnox tablets at home and later woke to find himself lying on a woman's couch wearing a dress.

The committee also had 104 reports of hallucinations and 62 reports of amnesia since the drug, known generically as zolpidem, was released in 2000.
 
fuckin i love the shit but i usually start with 5 tablets and forget what ive done and eat the whole 20 in a few hours.. ccosts a fucking fortune
 
Remember that bloke out of REM (think it was Peter Buck) who flipped out on an airplane? He took zolpiden and just 2 glasses of wine. Got of the charge because of top lawyer & character witnesses like Bono out of U2 (not that I like him, but he carries a lot of weight in the UK at least).
 
I can vouch for Zolpidem making me do very strange things. I never understood what people meant when they say that alcohol or benzos "lower inhibitions"... but zolpidem? that shit turns me into a monster! It actually reminds me a LOT of PCP.
 
Jamshyd said:
I can vouch for Zolpidem making me do very strange things. I never understood what people meant when they say that alcohol or benzos "lower inhibitions"... but zolpidem? that shit turns me into a monster! It actually reminds me a LOT of PCP.

Like PCP, except it's legally prescribed, isn't a controlled substance and is the prefered sleeping agent. Nitrazepam doesn't have all these effects.
 
Sleep medication linked to bizarre behaviour
12:44 06 February 2007
Roxanne Khamsi

New evidence has linked a commonly prescribed sleep medication with bizarre behaviours, including a case in which a woman painted her front door in her sleep.

UK and Australian health agencies have released information about 240 cases of odd occurrences, including sleepwalking, amnesia and hallucinations among people taking the drug zolpidem.

While doctors say that zolpidem can offer much-needed relief for people with sleep disorders, they caution that these newly reported cases should prompt a closer look at its possible side effects.

Zolpidem, sold under the brand names Ambien, Stilnoct and Stilnox, is widely prescribed to treat insomnia and other disorders such as sleep apnea. Various forms of the drug, made by French pharmaceutical giant Sanofi-Aventis, were prescribed 674,500 times in 2005 in the UK.

A newly published report from Australia’s Federal Health Department describes 104 cases of hallucinations and 62 cases of amnesia experienced by people taking zolpidem since marketing of the drug began there in 2000. The health department report also mentioned 16 cases of strange sleepwalking by people taking the medication.
Midnight snack

In one of these sleepwalking cases a patient woke with a paintbrush in her hand after painting the front door to her house. Another case involved a woman who gained 23 kilograms over seven months while taking zolpidem. “It was only when she was discovered in front of an open refrigerator while asleep that the problem was resolved,” according to the report.

The UK’s Medicines and Healthcare products Regulatory Agency, meanwhile, has recorded 68 cases of adverse reactions to zolpidem from 2001 to 2005.

The newly reported cases in the UK and Australia add to a growing list of bizarre sleepwalking episodes linked to the drug in other countries, including reports of people sleep-driving while on the medication. In one case, a transatlantic flight had to be diverted after a passenger caused havoc after taking zolpidem.
Hypnotic effects

There is no biological pathway that has been proven to connect zolpidem with these behaviours. The drug is a benzodiazepine-like hypnotic that promotes deep sleep by interacting with brain receptors for a chemical called gamma-aminobutyric acid. While parts of the brain become less active during deep sleep, the body can still move, making sleepwalking a possibility.

The product information for prescribers advises that psychiatric adverse effects, including hallucinations, sleepwalking and nightmares, are more likely in the elderly, and treatment should be stopped if they occur.

Patient advocacy groups say they would like government health agencies and drug companies to take a closer look at the possible risks associated with sleep medicines. They stress that strange sleepwalking and sleep-driving behaviours can have risky consequences.

“When people do something in which they’re not in full control it’s always a danger,” says Vera Sharav of the New York-based Alliance for Human Research Protection, a US network that advocates responsible and ethical medical research practices.

Tried and tested

“The more reports that come out about the potential side effects of the drug, the more research needs to be done to understand if these are real side effects,” says sleep researcher Kenneth Wright at the University of Colorado in Boulder, US.

Millions of people have taken the drug without experiencing any strange side effects, points out Richard Millman, a professor of medicine at Brown Medical School and director of the Sleep Disorders Center of Lifespan Hospitals in Providence, Rhode Island, US. He says that unlike older types of sleep medications, zolpidem does not carry as great a risk of addiction.

And Wright notes that some of the reports of “sleep-driving” linked to zolpidem can be easily explained: some patients have wrongly taken the drug right before leaving work in hopes that the medicine will kick in by the time they reach home. Doctors stress that the medication should be taken just before going to bed.

The US Food and Drug Administration says it is continuing to "actively investigate" and collect information about cases linking zolpidem to unusual side effects.

The Ambien label currently lists strange behaviour as a “special concern” for people taking the drug. “It’s a possible rare adverse event,” says Sanofi-Aventis spokesperson Melissa Feltmann, adding that the strange sleepwalking behaviours “may not necessarily be caused by the drug” but instead result from an underlying disorder. She says that “the safety profile [of zolpidem] is well established”. The drug received approval in the US in 1993.

New Scientist
 
There has been many a time where Stilnox (Ambien/Zolpidem tartrate) has made me do wierd things. Wether it be sleep walking/sleep talking/sleep Bluelight Posting (they're the best), I tend to do wierd shit, unless I'm tucked in bed.

I never really worry about things I do under the influence, but people I'm around tend to get rather worried.
 
I've been insufflating ambien for the past 2 years (daily past year), and the funny thing is I act nearly as bizzare on it now as i did in the beginning. Your logic becomes completely distorted on zolpidem unless you set some clear "thinking guidelines" before you take it. Even then you can run into problems. But all these people entertaining themselves with midnight bicycles rides on the highway and soap eating, whatever, seem irresponsible to me. It's easy to restrict yourself and say, alright, just don't eat anything or indulge in any drugs, or you will not be able to stop, etc. On a different note, it's a great anti-depressant for me.
 
lyXw33d said:
I've been insufflating ambien for the past 2 years (daily past year), .

^^^I was pretty hardcore into it for a while too ......had to cut back alot due to its bizzare impact on my memory. Have you noticed any memory problems from your daily use???
 
this might be an old topic but anyway ill post

if its the sleeping thingy called stilnoct ive had some sleepwalking experiences
about 2 weeks ago i used one its like 10 mg or something i was sitting on my computer and went to bed 10 min later next morning i wake up realy sweety all my cloths on i find the package of stilnock on my computerdesc finding out that there is missing 6 pills and about 4 less cigarets left clothing all over my room basicly a big fucking mess ive ripped out all my clothing form the closet and thrown it around the room spilled alot of coffie and water^^ and 1 week ago this happens again this time ive eaten 4 pills and made a big mess again :(

allover im happy with the pills no im keeping them in my bathroom instead of on my computer desc who know's maby its 10 next timeXD well atleast its a very nice pill to fall asleep from you feel like your on a floating blanket and everything around you floats quite fun:)
 
Last edited:
haribo1 said:
Like PCP, except it's legally prescribed, isn't a controlled substance and is the prefered sleeping agent. Nitrazepam doesn't have all these effects.

wait a second, ambien isn't a controlled substance in your part of the world? Sweet.
 
I've gotten the odd swirlygig visual off ambien but never any strange behavior. I find it to be a nice sleeping pill. A friend IV'd it (yes I know) and said it gave him an odd sort of rush followed by an overall strangeness.
 
Top