SAM-e and MDMA

[AylaV]

so from my understanding the metabolic process involved with MDMA is as follows:

MDMA -->CYP450 demethylenation to DMMA --> O-methyltransferase + S adenosyl methionine -->HMMA

Would this mean that taking Sam-e (S adenosyl methionine) would increase levels of HMMA? This is the metabolite I believe they test for in urine tests, but that's no huge concern to me. I'm just curious if this would detract from the bioavailability of MDMA.

In easier to understand terms, It looks like if I supplement with Sam-E that it would detract from the effects of MDMA. Is this true?

 

[ABCDFG I Ate The E]

probably get a better answer in advanced drug discussion? could be wrong though.

 

[AylaV]

I was honestly thinking that, but since it was ecstasy related I posted here. I was torn about it. Wasn't sure if this was an advanced question or not >.<