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Misc regiment of Rotating drugs to avoid addiction

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Candy_Raver

Candy_Raver

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Aug 7, 2008
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For me personally there is one state I hate more than anything else and its the state of being sober. I must be intoxicated everyday, or else life is boring.

I was wondering if anyone has worked out a regiment to where you can get high everyday, by rotating the drugs that hit a different neurotransmitters so you don't have an issue with building up a tolerance or getting an addiction.

For example:

Day 1: Use stimulants, and drugs that effect the dopamine system. Amphetamines, cocaine, methamphetamine etc.. They hit your dopamine receptors.
Day 2: Use cannabis as it hits your CB1 cannabis receptors.
Day 3: Use MDMA as its a serotoninergic, and affects your serotonin system.
Day 4: Use disassociatives such as ketamine, DXM, MXE etc... they hit your NMDA system.
Day5 : Use hallucinogens as it also affects your specific serotonin receptors.
Day 6 : Use opiates, and they affect your opiate receptors.
Day 7 : Use benzos as they hit your GABA receptors.

Fill in day: Soma, its a muscle relaxer and dosn't hit those specific system it can be mixed in some of the regiments.

Repeat again for the next week. I think the regiment can be modified, as long as you hit a different receptor system for the week you should be fine.

If this model can be put to use, it prevents addiction since you don't constantly bombard the same neurotransmitter, so it prevents your brain from being rewired say if you abused dopamine based drugs.

I was wondering if anyone has ever used such a regiment where you hit your different neurotransmitters on different days so you don't get a tolerance to the compound or to avoid addiction.

-PLUR
 
Just because you're not physically addicted to a particular substance, does not mean you're not addicted to drugs.
 
^ Indeed.

The physical dependence vs psychological addiction is a big discussion - you may avoid the former with what you suggest but not the latter. Essentially with that regime you are training yourself not to be sober. That is currently my biggest issue - not a dependence on any one drug, but a difficulty with getting through my days without a substance on board. I understand where you are coming from, but this regime is not sustainable IMO, and the psychological aspects of addiction are often the hardest to manage.

Using amphetamines and serotonergic drugs several days a week, week in week out, is going to take it's toll, both mentally and physically. Weekly MDMA use is not a good idea. Weekly hallucinogen use is not a good idea. What's to stop you breaking your schedule too - using benzos to help the crash after 2 days of amphetamines and MDMA, smoking weed when you are high, taking opioids that little bit more often, or benzos to help you sleep when you're up on stims?

I don't know what lifestyle you lead, but trying to fit in weekly days where you take a load of ketamine, or psychedelics, or MDMA is going to be tricky I imagine?

Tolerance can definitely set in with once weekly use too, especially for benzos and opioids.

Things are also not as clear cut as you think here. The dopaminergic reward pathway means dopamine plays a role in more than just amphetamine use. Related reading - the basic biology of drug addiction :)
 
The bigger question is has anyone been successful with such a drug regiment to where as long as you rotate the drugs that bombards a different pathway you can prevent addiction because your not bombarding the same neurotransmitter all the time.

I have been interested in this topic for a very long time.

-PLUR
 
I'll bet using drugs like this will kill you faster than just one drug.

Just because hypothetically it may appear not to hit the same receptor, doesn't mean you wont have problems.

I can see this extreme poly drug abuse not only failing to prevent addiction, but provoking some severe psychiatric issues.
 
^^ You will still be activating the dopamine reward system with most of those drugs however..

I have not tried it but I see a lot of reasons why that would not be sustainable. It's just not a healthy plan and you'll give yourself a lot of problems.
 
The problem with this is there really is no medicinal value to what you are doing other than "for fun". My best bet is that with your plethora of drugs you will end up mixing them rather than taking them on a regiment.

The best way not to get addicted? Take "sobriety breaks" for a week to a month every now and then.



tricomb said:
I'll bet using drugs like this will kill you faster than just one drug.
Click to expand...

Certainly an interesting point. From a biological view this seems to make sense.
 
If you are using drugs all day every day and shit you are not preventing addiction.

Also, I agree with the dude who said you'll probably end up combining them.

I mean its a bit of a hassle to acquire drugs from completely different categories and crap too.
 
Seriously, this is just a delusional way to rationalize getting high everyday. Some people get high everyday and function normally in life, but these people are using ONE drug. I don't think your body, let alone your precious mind, will put up with this shit for long.
 
The first thing that ran through my head was to just laugh, ask you to do it, and tell us how long you lasted doing that. I love drugs as much as the next person, but that would kill you with a fuckin quickness!~
 
you have gone to far, i love it.....applying this type of businesslike logic to being fucked up 24/7?..at least your committed. the soma "fill in as needed" post script is a nice touch.
 
I think it is great that you are thinking outside of the box and that is a good thing. As far as the rotation on drugs, I lived with a couple of roomies who did their very best to stay high all the time, & I think they were very successful. Although they never stuck to a scheduled regimen, as you put forth, they had very good connections & usually managed to find something different about 5 times a week, and in this way they seemed to have kept their tolerance low.
BTW- Alcohol can easily be substituted every couple of days & I don't even like alcohol, but I can find ways to use it that are easier to get down, like jello shots.
 
Another reason why this would fail, for me anyways.

I like to use certain drugs in certain situations. And you wouldn't be able to use a drug that fits your occasion.

If you use drugs like this, there is almost no way you could be employed, or receive an education.
 
tricomb said:
Seriously, this is just a delusional way to rationalize getting high everyday. Some people get high everyday and function normally in life, but these people are using ONE drug. I don't think your body, let alone your precious mind, will put up with this shit for long.
Click to expand...

There exist degrees of highness. I use more than one drug everyday and I don't feel the need to put myself in the hospital to do so. Some folks can use responsibly & still get to work everyday
 
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tricomb said:
Seriously, this is just a delusional way to rationalize getting high everyday. Some people get high everyday and function normally in life, but these people are using ONE drug. I don't think your body, let alone your precious mind, will put up with this shit for long.
Click to expand...

I have been on methoxetamine all week this week, and the tolerance to that drug is starting to get to me. Which is why I came up with the idea of setting up some sort of regiment so you can use every day but a different drug.

Well take the case of a functional drug addict, that's addicted to one drug. Well since your rotating your drugs you don't become dependent on one drug, so the harm is spread out instead of constantly pressing one receptor. If a drug addict can be functional on one drug, why can't one be a completely functional poly-drug addict? A small minority of functional drug addicts do exist, I'm pretty sure within that community of people there are many more functional poly drug addicts out there.

-PLUR
 
The thing is though, weekly MDMA use will still fry you. Weekly psychedelic use may well do all sorts of bad things to your state of mind. Amphetamines, MDMA and psychedelics (many anyway) all act on serotonin. Most of those drugs bar benzos activate your dopamine reward pathway. Weekly ketamine use could still damage your bladder, and ketamine is dopaminergic too. Weekly use of many of those things will still cause an increase in tolerance.

You'll end up wrecking more of you doing this, not reducing harm.. cruising for depression, psychosis and a very unhealthy body, not to mention a reliance on drugs in general which is just as much of an addiction as anything else, and harder to kick too as who can manage to avoid all drugs all the time?
 
Candy_Raver said:
I have been on methoxetamine all week this week, and the tolerance to that drug is starting to get to me. Which is why I came up with the idea of setting up some sort of regiment so you can use every day but a different drug.

Well take the case of a functional drug addict, that's addicted to one drug. Well since your rotating your drugs you don't become dependent on one drug, so the harm is spread out instead of constantly pressing one receptor. If a drug addict can be functional on one drug, why can't one be a completely functional poly-drug addict? A small minority of functional drug addicts do exist, I'm pretty sure within that community of people there are many more functional poly drug addicts out there.

-PLUR
Click to expand...

The point is, it doesn't matter what drug hits what receptor if you can't even hold down a job or go to school. Most of the damage drugs do are not a result of the receptor they activate, but the lifestyle. And this lifestyle IMO will end up with you in a state mental hospital. There is no "schedule" you can follow to be high everyday and avoid addiction, or avoid MORE severe psychiatric problems.

I know this strategy might look good on paper, but man, in real life I'll bet if you were to see the result of this pattern of drug use you would be scared or scarred.
 
^ Yeah I really struggle to see how you could possibly hold down school or work or anything taking dissociatives or psychs or MDMA, let alone the toll that schedule would take on you.
 
it has been proven that methamphetamine, heroin(and other powerful opiiods), crack/cocaine, and alcohol are the most addictive drugs...so if ur using those u might get addicted...

oh shit i forgot nicotine...the number one (but not to me...)
 
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