(zonk)
Bluelighter
- Joined
- May 24, 2008
- Messages
- 687
So based on their structural simplicity I've been interested in APV based compounds. I had ordered some D-homoglutamate but the taste while not too strong was the right kind of yuck to make me hold off on any real experimentation as i would have to ingest ALOT.
*** So my question is about the piperazine based analogs and their dosages. I've seen mention of them being "the most potent known" to what looks like 1/3 of ketamine or less. I seen something that says it can displace mk801 at 30nM but binding profile is .8uM to 2uM depending on the receptor subunit. Selfotel was supposed to be the mist potent, I'm assuming PMPA(tenofovir intermediate) is close and midafotel(D-CPPene) is less potent from what I can tell. Their half lives are short like ketamine which is good. Dosages are listed as .5-2mg/kg and tested from 100-800mg. Are these slow drip infusions, anesthetic dosages? How much would be need for ketamine like effect(hole)???
*** So my question is about the piperazine based analogs and their dosages. I've seen mention of them being "the most potent known" to what looks like 1/3 of ketamine or less. I seen something that says it can displace mk801 at 30nM but binding profile is .8uM to 2uM depending on the receptor subunit. Selfotel was supposed to be the mist potent, I'm assuming PMPA(tenofovir intermediate) is close and midafotel(D-CPPene) is less potent from what I can tell. Their half lives are short like ketamine which is good. Dosages are listed as .5-2mg/kg and tested from 100-800mg. Are these slow drip infusions, anesthetic dosages? How much would be need for ketamine like effect(hole)???