Opioids Plugging stopped working. What am I doing wrong?

[cstm]

After 4 months of being off pain meds, I started back 3 weeks ago. My Dr. cut me down to just 15mg Morphine ER twice a day
and 5mg oxy twice. I normally take all my mg for the day at once, but I wasn't getting anything from the 40mg combined. I
did a lot of research on the site and decided to try plugging. The first time, nothing happened. The second time WOW!! I hadn't
felt like that in years. It was great!! Yesterday,, I ran out of the Tagamet I normally take so I substituted 450mg of Zantac.
I know this is a poor substitution as the Zantac only acts on CYP2D6 and does nothing for CYP3A4, which is primarily
responsible for the metabolism. To try to make up for that, I added 4 Coricidin (30mg DMX and 4mg Chlorpheniramine) and
tossed in 30mg Dextroamphetamine (I am prescribed 40mg a day). Nothing happened, but I wasn't all that surprised. Today,
I went back to the Tagamet but still added the Coricdin for the DMX effect on tolerance. Everything else was the same, but
again nothing happened. After an hour, I snorted another 5mg oxy and 1mg K-pin. Still nothing so I gave up for the day. I
can't figure out what happened and why it didn't work when it's been working wonderfully for the past 5-6 days. From the
searches I've done on this site and elsewhere, I can't see why the Coricidin would have a negating effect like this.

If anyone has any ideas as to why it stopped working for me, I would greatly appreciate any input you have to offer. I really
want to get back to the WOW! Thank you for your time in reading this and for any insight you have to offer.

 

[Thou]

You're abusing your medicines.

Stop doing that.

Your request is too specific I fear for anyone to help you out otherwise just take a fucking break or something.

If your preferred drugs have stopped working and tagamet is something you utilize now continuously, odds are you're fucked and need to cut back.

 

[missmeyet?]

Hmm, with all due respect Thou, maybe you didnt read his post carefully. Plus you seemed a little harsh in your answer..."You are abusing your meds, stop doing that"??? Dont 95% of the people on BL abuse meds??

OP, Im not sure why you would use the coricidin with the morphines..also, you said you snorted your oxy, you do realize that you will have better BA by just taking it orally, right? In regards to your using the meds rectally, the one thing that immediately comes to mind for me is, are you by any chance constipated right now? This is one of the most frequent problems that occur when you "plug" meds, especially opiates/opioids. If you have BM in your rectum then it will generally absorb the meds you are placing there rather than allowing it to be absorbed by your intestines.

 

[cstm]

I did take a break. 4 months and I've only been back on them for 3 weeks, as I said in my post. Thank you for your concern.

 

[Thou]

I'm sorry I sounded cross though...

Hmm, with all due respect Thou, maybe you didnt read his post carefully. Plus you seemed a little harsh in your answer..."You are abusing your meds, stop doing that"??? Dont 95% of the people on BL abuse meds??

They're not supposed to this isn't opiophile.



My recommendation still stands it's likely you should forget about this class of drugs for some time perhaps and maybe it's likely you're abusing these meds?

Are you using these for a legitimate purpose from a physician or illicitly and is it for a medical reason or a recreational one?

 

[cstm]

I took the Coricidin for the DMX tolerance stabilizing effect and Chlorpheniramine is an antihistamine and a potentiates opioids. Yes, I do know the bioavailability is higher for oxy taken orally, but I was trying to get back to WOW. Lastly, I am not constipated at all since I've been off the opioids for months. That was a good suggestion though and I appreciate your thoughts! Thanks

 

[Thou]

I didn't understand that you're trying to get analgesic or recreational effects doing this?

 

[cstm]

Both actually. I've been on 30mg morphine and 15mg oxy for years and this dosage just doesn't allow me to be active at all. I can take it as prescribed and stay in bed all day as that's the only thing that makes it tolerable, or I can take it at once to equal the dosage that is therapeutic for me and be active for about 8 hours. That said, after being off them for an extended period, I am feeling a buzz. Yes, it is enjoyable and yes I do like it. But fear not, it will go away some enough so put your mind at ease.

 

[Thou]

So you're saying that your prescribed dosages keep you bedbound but when you abuse it you're active?

You don't have pain issues when you misuse it like that, IE: running out of meds early?

I'm not a teetotaler I don't care if you get high or not I prefer when people are happy I 've only taken this stance because you didn't mention context with your post I said 'pain medicine' but you're acting as though you take them differently than prescribed. I understand that doctors are limited and the best of those limited are frightened dullards that are beyond help, but unless you tell me what you're trying to increase your tolerance for I won't be able to give you a definite answer.

IF your dose isn't working and you're plugging it, I'd say a short break could benefit you. Maybe use kratom for that period.

You mentioned dxm use that makes sense though coricidin is a shitty product for tolerance mitigation you should be using delsym or similar XR preperation of dxm (polistirex).

Also, maybe either telling your doctor to up the dose or change opioid medicines if you're still in pain. Those are small preperations you mentioned.

Then again if you're not in pain you shouldn't be fucking with them unless you need to.

 

[cstm]

I'm saying quite plainly, the dose I'm prescribed is not a therapeutic level to allow me to be up and around. Taken as directed, my back hurts too much to be active. I am trying to lessen my tolerance level to take advantage of the FOUR month break I just took. I don't run out of meds early and I don't have to miss days ever. That's why I'm trying to find ways to make the amount I'm given daily work. I didn't know that Coricidin was a bad product. Why is that?

You seem less interested in giving insight and more in TRYING to judge me. I am not interested in what you think of me or of how I manage my pain, but in learning ways that enable me to do so.

 

[Thou]

You want an extended release dxm for tolerance. Delsym brand is dxm polistirex which lasts for 12 hours, or memantine preferably but unless you buy it yourself it can be hard to get off-label from your doctor and your insurance may not cover it.

I'm not trying to judge you at all I just didn't understand the situation properly at first and came off abrasively my apologies. The break you mentioned threw me I couldn't conceive that anyone getting pain meds could go off of them for a while just to get tolerance back but I suppose you're desperate. That resolve is admirable.

If you're looking for pain coverage and your dose isn't helping you have you spoken with your doctor at all? Is that not a possibility in your situation? I don't know your age or condition but you are still at a low dosage compared to some of the more chronic cases I've seen. How long were you on this dose before you took that break?

Maybe supplementing with small doses of kratom could level it off a bit perhaps? I'd suggest a better analgesic if we lived in some greater universe where one existed.

 

[cstm]

My doctor lowered my dose to this level because with my time off and my tolerance lowered, he says this is all I need. He said he doesn't want to waste all that time off by setting the dose higher than I need. I have told him it's not working. but he is steadfast. Before my break I was at 30mg morphine three times daily and 15mg oxy four times. Big jump going from 150mg a day to 40mg. I asked if we could just do 30mg morphine AM and 15mg PM with 4 5mg oxy rather than 2. That way I could have at least 8 hours a day that the pain would be tolerable for me to get up and do things, go places, just get out of bed! He said not right now.

I don't know what kratom is, but I will look it up now. I spent most of that 4 months in bed, gained a bunch of weight and became pretty depressed. I don't want to be there anymore and I will do whatever I have to just to live life again.

Thank you for your suggestions. If there's anything else your can think of, please let me know.

 

[Thou]

I'm afraid I can't really offer much else not that I've offered much at all. Look into memantine and dxm on preventing tolerance with opiates it works well with other things opiates I don't know about though.

Good luck I hope you feel better and get more adaquate help than I can provide.

 

[Tommyboy]

I'm saying quite plainly, the dose I'm prescribed is not a therapeutic level to allow me to be up and around. Taken as directed, my back hurts too much to be active. I am trying to lessen my tolerance level to take advantage of the FOUR month break I just took. I don't run out of meds early and I don't have to miss days ever. That's why I'm trying to find ways to make the amount I'm given daily work. I didn't know that Coricidin was a bad product. Why is that?

You seem less interested in giving insight and more in TRYING to judge me. I am not interested in what you think of me or of how I manage my pain, but in learning ways that enable me to do so.

Sadly if you find a way to make this dose work it will probably lose its effectiveness once again after your tolerance catches up with you. Your best bet is to seek out alternative means of helping alleviate your pain. There are shots, exercises, weight loss, diet, physical therapy, and other means of helping control your pain along with the meds.