Heroin Perparing a shot for the morning?

[MikeySpikes]

This chick i know told me she whould perpare her morning shot the night before, i have always wondered if this was smart because of the possible bacteria build up or the liquid interacting with the heroin molicules and converting the substance to something less potent which i believe i read on this forum somewere it can change into morphine or something idk soinds crazy to me!? Thank you!

Edit: i am using china white in a cold mix. Using poland spring water and a clean rig!

 

[muvolution]

If it is only 6-8 hours and you keep the syringe in the fridge or prepare it with sterile bacteriostatic water, it will keep for a short amount of time. Nothing over 12 hours, though as heroin does break down into morphine in solution.

 

[Cane2theLeft]

It's true that diacetylmorphine (heroin) will hydrolyze into 6-monacetylmorphine and morphine however this takes a lot longer than the 8 hours or so that it would be left overnight...

Electron-capture gas-liquid chromatography was used to study the spontaneous hydrolysis of heroin in phosphate buffer (pH 6.4 and pH 7.4) at 23 degrees C. Aliquots of solution were taken over a 24-h period. After extraction at pH 8.9 into propan-2-ol (10%)-ethyl acetate, deacetylated products were made into hepafluorobutyrate derivatives which were analyzed quantitatively using nalorphine as the internal standard. Heroin decomposes to 06-monoacetylmorphine (06-MAM) under these conditions. Further decomposition to morphine was not observed. Spontaneous hydrolysis was faster at pH 7.4 (first-order rate constant, 9.6 x 10-5 min-1) than at pH 6.4 (first-order rate constant, 3.0 x 10-5 min-1). In 24 h, the decomposition to 06-MAM was 13 and 4%, respectively.

http://www.ncbi.nlm.nih.gov/pubmed/688091

The bigger concern was, as you mentioned, the bacterial growth. Unless you have sterile ampules of diamorphine and sterile gear, bacteria will rapidly grow in your shot increasing the harm. Bacteriostatic water would be beneficial as would utilizing other strategies to slow bacterial growth such as refrigeration, however you're still increasing the risk for little benefit by doing this.

EDIT:

Nice ninja, mu

 

[scottd420]

You are absolutely right, my friend. The two acetyl groups that are attached to morphine which makes heroin are able to snap off of the molecule while in solution. Some people say it takes 12-24 hours, but I've heard it has happened faster--all dependant on what's in your water (dissolved minerals, temperature, light etc...). So, in short, by morning you could have a syringe full of morphine; not for sure, but enough of a chance that I wouldn't bother. A shot only takes a sec to prepare, so I'd say just do up a quick one. Most people prefer the rush and high of heroin over morphine, so unless you're waking up brutally sick and just cannot wait, I'd say save it. If you do decide to try it, you will be able to tell by the pins and needles feeling from the histamine release during the morphine rush.
Good luck and have fun, Mikey.

-Scott

 

[muvolution]

I see you are quite ninja, Cane. I am a ninja, too.


If you are going to do this and are concerned about the Heroin breaking down, you could get Sodium Chloride sterile solution for injection instead of plain sterile water as the link Cane posted seems to indicate that a lower pH slows the process down.

 

[ActiqAnnie]

I hope this isn't too off-topic but I'm tired and rather than looking this up/figuring it out for myself, does anyone know if a pre-prepared solution of oxymorphone would degrade?

I also prep shots in advance because I shoot pills and not heroin. So the whole song and dance with the micron filter is easier to do in a batch preparation. I do use bacteriostatic water and refrigerate everything, but it seems to me that day old solution isn't nearly as potent as the fresh stuff.

 

[MikeySpikes]

Thank you guys, i enjoy the ritual of setting up the rig almost as much as i do getting high you know? Plus i whould be too tempted to do the shot now but again thank you guys very much!

Edit: i am using brooklyn china white. Cold mix.

 

[muvolution]

I hope this isn't too off-topic but I'm tired and rather than looking this up/figuring it out for myself, does anyone know if a pre-prepared solution of oxymorphone would degrade?

I also prep shots in advance because I shoot pills and not heroin. So the whole song and dance with the micron filter is easier to do in a batch preparation. I do use bacteriostatic water and refrigerate everything, but it seems to me that day old solution isn't nearly as potent as the fresh stuff.

OM is stable. They have vials of solution, which wouldn't exist if it degraded. Ever seen a vial of heroin? It's usually just powder and you snap off the top and add water.

If your shots feel weaker after setting around, try Sodium Chloride solution for injection (Hospira makes 30mL vials - the green label not the pink label that is on bac. water)

 

[Cane2theLeft]

Annie, I think Mikey's post here about the ritual may be relevant to your question - via classical conditioning, you may have paired the ritual and effects and by removing the ritual it might actually change the effect enough to where you perceive it to be a little less potent.

With heroin, the diamorphine ampoules actually come in a powder and they have to add water immediately prior to injection to avoid hydrolysis. Oxymorphone ampoules do not require reconstitution so I am skeptical that there would inherently be any type of degradation but I can't say for certain.

EDIT:

FFS mu, you're making me look bad

 

[scottd420]

Cane, from my experiences I would agree with you. I've only seen photos of diamorphine in sealed vials containing lipophilized powder sometimes with a pre-loaded syringe of bacteriostatic water for reconstitution, just like the medication for diabetics that makes the liver produce insulin incase of emergency in the situation of total pancreas failure, as it is not stable.
Personally I'm a hydromorph guy and I know that molecule does not degrade in solution since there are generic vials and brand name Dilaudid vials of pre-mixed drug available. Going with the idea of strikingly similar molecules should give strikingly similar physical properties, the oxymorphone should be stable in solution under the same environmental conditions as well.

 

[MikeySpikes]

I hope this isn't too off-topic but I'm tired and rather than looking this up/figuring it out for myself, does anyone know if a pre-prepared solution of oxymorphone would degrade?

I also prep shots in advance because I shoot pills and not heroin. So the whole song and dance with the micron filter is easier to do in a batch preparation. I do use bacteriostatic water and refrigerate everything, but it seems to me that day old solution isn't nearly as potent as the fresh stuff.

I whould think if you decided to "mass produce" your solution. You may get diffrent quality per shot. I know that when i try to do that the bottem of solution is more concentraded due to the particals slighly settling to the bottem of the spoon or cap. Maybe these guys are right and it may be a placibo effect?

 

[ActiqAnnie]

I think that personally, the issue is really that I'm dosing too often. There may be a ritualistic component, but the fact is that I've always shot pre-prepared solution. The best hit of the day is the first in the morning. Best rush, most discernible effects. Then I'm just probably shooting WAY too much and redosing far far too often to properly enjoy. I find myself sometimes redosing in less than an hour, and I've gone from enjoying 10mg greatly to quantities near 40mg (and constant redosing) not doing much. I'm not good at controlling my quantity and I've pushed my tolerance up a lot recently.

Thanks for the insights!

 

[Cane2theLeft]

^ yeah, that probably is the explanation. I've always found redosing of opioids to be far less effective and I've seen the same sentiment echoed around here constantly.

 

[MikeySpikes]

I think that personally, the issue is really that I'm dosing too often. There may be a ritualistic component, but the fact is that I've always shot pre-prepared solution. The best hit of the day is the first in the morning. Best rush, most discernible effects. Then I'm just probably shooting WAY too much and redosing far far too often to properly enjoy. I find myself sometimes redosing in less than an hour, and I've gone from enjoying 10mg greatly to quantities near 40mg (and constant redosing) not doing much. I'm not good at controlling my quantity and I've pushed my tolerance up a lot recently.

Thanks for the insights!

I just shot up and i feel just beacuse i talked about it and like phened my self out lol the shot was that more enjoyable. I did the same thing as you. I whould shoot and redose before i could come down. Yes i whoild stay high, but how can you judge how high you are because u never come down. Eversince one time I ran out an got sick cause i couldnt get to my connect my car was in the shop. Now i alaways kind of toture my self so to speak and try to come down a little before redosing so i appreciate the shot. I feel amazing

 

[Secobarbital]

I whould think if you decided to "mass produce" your solution. You may get diffrent quality per shot. I know that when i try to do that the bottem of solution is more concentraded due to the particals slighly settling to the bottem of the spoon or cap. Maybe these guys are right and it may be a placibo effect?

There are many people around here who do it, with HM, morphine, and oxycodone too. The dissolved chemicals do not "settle" in water. They are evenly distributed in the water until no more can be dissolved. This is called "saturation".

 

[Cane2theLeft]

Opioids are VERY water soluble - whatever particles are floating around or settling, are cuts impurities or inactive ingredients that you don't want in your shot and it's shit that you do NOT want in your veins. This is precisely why you need to filter better.

 

[MikeySpikes]

There are many people around here who do it, with HM, morphine, and oxycodone too. The dissolved chemicals do not "settle" in water. They are evenly distributed in the water until no more can be dissolved. This is called "saturation".

I see what your saying, but in my experience with iving roxis, the shots i whould take varied. It has been a while since then. It was probley due to my own human error. The heroin i get mixes better than tang or ne " just add water and stir".

 

[Secobarbital]

Yea, the thing is, water will hold a ton of heroin. A cc of water will hold only 60mg of morphine though, or 100mg of oxycodone. These chemicals become saturated. I have known of quite a few people over the years who did not put enough water in oxycodone. I watched a girl put 1 cc of water in 3 80's, and not go back for a 2nd rinse. She just left 140mg of OC in the spoon. I casually told her I was going to make a shot in the same spoon, and just added like 20mg or so, and proceeded to make sure I washed out the other 140mg. If you are drawing better shots off the "bottom" or they are varying, you may be saturating your water with oc, and the variations would be where you are pulling bits of solid oxycodone into the rig.

 

[Cane2theLeft]

^ thank you for adding that, it's a great point that I failed to consider when I posted above.

 

[muvolution]

she was asking about oxymorphone, no?

OM, I believe, has a solubility of like 200+mg/mL. Given that it is so potent, I doubt you will ever fully saturate a solution.