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  • BDD Moderators: Keif’ Richards | negrogesic

Opioids Paracodein/Dihydrocodein 10mg with a film around the pills.

Hyperfocus_Flow_Oddball

Hyperfocus_Flow_Oddball

Greenlighter
Joined
Oct 14, 2024
Messages
14
Location
Antwerp Belgium EU
Hello,

I got my hands on this stuff, and last time I crushed 4 pills and got a mild high.
Now, since the pills have a film around them, I suppose they are extended release, but since I got high from crushing and insufflating I guess no antagonist is present.

I will do some more research, but I wanted to ask:

* the pills contain a.o. stuff colloidal, wtf is that and can it work antagonistic? Also umstereat, wtf is that?

* the pills of 10mg are equal to 6.7mg dihydrocodein, which would be 2x as strong as codein, is this corrrect?

* codein is a prodrug, is dihydrocidein also a prodrug? And do prodrugs act as prodrugs when crushed and insufflated? And if not, how come by insufflating the metabolisation to the Morfine alkaloids happens in minutes?

* How much product do I gain by insufflating ergo bypassing the liver that breaks down upto 90% of some products?

* Furthermore, what dose would you people recommend for a severe high, nodding and decent euphoria at the least I mean?

* Any additional information you can give me is more than welcome!

I thank you you all and wish you all a wonderfull day/night!

Grtz from An Atypical Alienated Hyperfocus Flow Oddball

GENIUSLY FLAWED

INSANE GENIUS LOST IN DARKNESS LOOKING UP BUT ALL THE STARS ARE NOT WANTED NOW

POOR AWAY THE OCEANS AND SWEEP UP THE WOOD
FOR NOTHING NOW CAN EVER COME
TO ANY GOOD....

SHE WAS MY MIDNIGHT

MY NOON

MY TALK

MY SONG

I THOUGHT LOVE WOULD LAST FOREVER

I WAS WRONG...
 
DHC is slightly stronger than codeine without being metabolized, meaning you likely felt a placebo effect, got residual metabolism from the drip, or have a ridiculously low tolerance. You should be crushing and eating them. Snorting dhc, codeine and all pro drugs for that matter is a waste of time, energy, and drugs because you'll get higher if you just let your liver do it's job. Codeine and it's relatives need to be converted in the liver (cyp2d6, specifically) into active metabolites, so, in short, you're not "bypassing" anything other than the metabolism that actually makes the drugs work.
 
daturetard said:
DHC is slightly stronger than codeine without being metabolized, meaning you likely felt a placebo effect, got residual metabolism from the drip, or have a ridiculously low tolerance. You should be crushing and eating them. Snorting dhc, codeine and all pro drugs for that matter is a waste of time, energy, and drugs because you'll get higher if you just let your liver do it's job. Codeine and it's relatives need to be converted in the liver (cyp2d6, specifically) into active metabolites, so, in short, you're not "bypassing" anything other than the metabolism that actually makes the drugs work.
Click to expand...
I hardly believe this to be true, can you show me sources to back up your claims? Cause all my research said insufflstion is the way to go, and I am talking trustable scientific sources and I use the scientific research method, meaning starting with a scientific encyclopedia and go from there. I can provide scientific sources like researchgate that back up insufflation as a primary recreational ROA.

Also your ad hominem that I would have had a placebo effect is total bs, since I am a polydrug abuser in extremis for over 20yrs now snd I always expect to feel nothing or very little and I figured these pilks to do nothing, also the day before I did what you said with 20 pills and swallowed and felt jack shit.

1 thing you have correct, it has bern +-7yrs since I did any opioids/opiates so yes, 0 tolerance.

Pls answer me ASAP and back yourself up with decent sources before I fucking waste this stuff!!!

I thank you for your time and effort.

Respect and peace.

Grtz.
 
Hyperfocus_Flow_Oddball said:
I hardly believe this to be true, can you show me sources to back up your claims? Cause all my research said insufflstion is the way to go, and I am talking trustable scientific sources and I use the scientific research method, meaning starting with a scientific encyclopedia and go from there. I can provide scientific sources like researchgate that back up insufflation as a primary recreational ROA.

Also your ad hominem that I would have had a placebo effect is total bs, since I am a polydrug abuser in extremis for over 20yrs now snd I always expect to feel nothing or very little and I figured these pilks to do nothing, also the day before I did what you said with 20 pills and swallowed and felt jack shit.

1 thing you have correct, it has bern +-7yrs since I did any opioids/opiates so yes, 0 tolerance.

Pls answer me ASAP and back yourself up with decent sources before I fucking waste this stuff!!!

I thank you for your time and effort.

Respect and peace.

Grtz.
Click to expand...

Pharmacokinetics of dihydrocodeine and its active metabolite after single and multiple oral dosing - PMC

The pharmacokinetics of dihydrocodeine (DHC) and its active metabolite dihydromorphine (DHM) were assessed after a single oral dose of DHC and after increasing doses of DHC at steady-state. Twelve healthy male volunteers (18–45 years, CYP2D6 ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
 
The active metabolite is dihydromorphine.

pharmaceutical-journal.com

How codeine metabolism affects its clinical use

Codeine is an established, familiar and widely used analgesic. It is considered a weak opioid, with a potency around one tenth that of morphine (i.e. 60mg of codeine is equivalent to around 6mg of morphine)[1]. Codeine is administered in doses of 15–60mg up to four times per day (maximum of...
pharmaceutical-journal.com pharmaceutical-journal.com
Look at the definition of prodrug. Then look at the wiki page for dhc. It's a prodrug. Essentially useless without metabolism. You're getting a fat placebo.
 
Hyperfocus_Flow_Oddball said:
I hardly believe this to be true, can you show me sources to back up your claims? Cause all my research said insufflstion is the way to go, and I am talking trustable scientific sources and I use the scientific research method, meaning starting with a scientific encyclopedia and go from there. I can provide scientific sources like researchgate that back up insufflation as a primary recreational ROA.
.
Click to expand...
And I could site sources saying snorting tramadol gives a wicked high and absorbs 500x better, doesn't mean it's true (e: technically, it does absorb better, but doesn't metabolize). If you snort tramadol, you skip the very large majority of metabolism to ODSMT, aside from the drip, you won't feel shit but a fucked up nose and maybe a slight snri buzzyness.
 
daturetard said:
The active metabolite is dihydromorphine.

pharmaceutical-journal.com

How codeine metabolism affects its clinical use

Codeine is an established, familiar and widely used analgesic. It is considered a weak opioid, with a potency around one tenth that of morphine (i.e. 60mg of codeine is equivalent to around 6mg of morphine)[1]. Codeine is administered in doses of 15–60mg up to four times per day (maximum of...
pharmaceutical-journal.com pharmaceutical-journal.com
Look at the definition of prodrug. Then look at the wiki page for dhc. It's a prodrug. Essentially useless without metabolism. You're getting a fat placebo.
Click to expand...
And the reason this says codeine is 10% strength of morphine, it metabolizes into morphine at a rate ~10%. Same as dhc.
 
daturetard said:
DHC is slightly stronger than codeine without being metabolized, meaning you likely felt a placebo effect, got residual metabolism from the drip, or have a ridiculously low tolerance. You should be crushing and eating them. Snorting dhc, codeine and all pro drugs for that matter is a waste of time, energy, and drugs because you'll get higher if you just let your liver do it's job. Codeine and it's relatives need to be converted in the liver (cyp2d6, specifically) into active metabolites, so, in short, you're not "bypassing" anything other than the metabolism that actually makes the drugs work.
Click to expand...
For me Dhc is a way stronger than codeine...i feel it ok....and withdrawl from dhc is much harder...beleive me..as to metabolizing prodrugs like codeine it's not nessesery to take it p.o......ofcourse better do it,cause it's stupid to sniff or inject pills,but....but-enzymes that convert for example codeine in morphine are not only in guts,but in the liver also....early 90...here H was still unavailable,so all the druggies in capital...and that was a 100-200 people learn how to extract codeine liquid from pills containing aspirin,coffeine and phenobarbital.......and all....i mean all using the liquid i.v.....and it was hellish itching,but effect was present and clear....no one died,no one got edema or anaphilactic reaction.......and every book says-codeine should not be given intravenously.......all drug addicts at that time do codeine just in that way...cause was very hard to get pills from pharmacy who can pop peroraly....and these pills(polish) were otc,very cheap and acid\base extraction was not hard to do....what a strange,freaky...crazy times......and few years later start the flood with high grade H and people started to die like flies
 
Nas47 said:
For me Dhc is a way stronger than codeine...i feel it ok....and withdrawl from dhc is much harder...beleive me..as to metabolizing prodrugs like codeine it's not nessesery to take it p.o......ofcourse better do it,cause it's stupid to sniff or inject pills,but....but-enzymes that convert for example codeine in morphine are not only in guts,but in the liver also....early 90...here H was still unavailable,so all the druggies in capital...and that was a 100-200 people learn how to extract codeine liquid from pills containing aspirin,coffeine and phenobarbital.......and all....i mean all using the liquid i.v.....and it was hellish itching,but effect was present and clear....no one died,no one got edema or anaphilactic reaction.......and every book says-codeine should not be given intravenously.......all drug addicts at that time do codeine just in that way...cause was very hard to get pills from pharmacy who can pop peroraly....and these pills(polish) were otc,very cheap and acid\base extraction was not hard to do....what a strange,freaky...crazy times......and few years later start the flood with high grade H and people started to die like flies
Click to expand...
Yeah they're in your liver but your liver gets the shit inside it from your stomach and very little of your blood is actually filtered through it, meaning that you would still need to eat the shit to metabolize it significantly. You're not gonna significantly convert it by snorting, but I believe you that it's (dhc) stronger.

Also, you'll get a weak rush from injecting distilled water.
 
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.I guess u don't know what i am talkin' about......This was not distilled water man....this was pure cod.phosph.-without any addulterants....High was goodd....every junkie in the capital do that shit in that time.....also-u got tramadol ampules,in some places injectable oxycodone and so on-they are as so strong using parenteral method----enzymes are in ur blood also....so this things about eating stuff to metabolize it are true,but only partially.....and rush from i.v. codeine was more potent than just take it orally...why u think these oldschool dopeheads do that shit?....most of them were graduated chemists...people enough good educated.....hey man-all this is personal experience...i am no talkin'shit here....listen what i say..as to snorting-idk never tried codeine or dhc in that method.....so maybe snorting don't work......don't know also about plugging or smoking this stuff...never got to tried and don't wanna do it.....and to extract codeine was purely because at that time here was absolute dry as to painkillers......and it works like poorman's morphine forreal....poverty and need learns u a lot of things u know...this stimulate creativity in some manner
 
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Nas47 said:
....poverty and need learns u a lot of things u know...this stimulate creativity in some manner
Click to expand...
Sounds a bit like Limpet_Chicken [RIP] he had prescription s.
For everything, and still, as UK-er, did a CWE on OTC Codeine.

Once in a while, to put too use his chemistry talent,
and making Propionyl-Morphine/ Heroine from it.
 
Nas47 said:
.I guess u don't know what i am talkin' about......This was not distilled water man....this was pure cod.phosph.-without any addulterants....High was goodd....every junkie in the capital do that shit in that time.....also-u got tramadol ampules,in some places injectable oxycodone and so on-they are as so strong using parenteral method----enzymes are in ur blood also....so this things about eating stuff to metabolize it are true,but only partially.....and rush from i.v. codeine was more potent than just take it orally...why u think these oldschool dopeheads do that shit?....most of them were graduated chemists...people enough good educated.....hey man-all this is personal experience...i am no talkin'shit here....listen what i say..as to snorting-idk never tried codeine or dhc in that method.....so maybe snorting don't work......don't know also about plugging or smoking this stuff...never got to tried and don't wanna do it.....and to extract codeine was purely because at that time here was absolute dry as to painkillers......and it works like poorman's morphine forreal....poverty and need learns u a lot of things u know...this stimulate creativity in some manner
Click to expand...
There's a miniscule expression of cyp2d6 in the blood and brain, much much less than the liver. Closer to 2 percent than 10 percent would get converted to morphine, just in a much quicker manner, providing you with whatever rush you experienced. I'm also not trying to talk shit, but placebo can have a crazy strong effect. If you're an opioid addict, it'll keep you from withdrawals by slowing down your system/stomach, so of course people take it when they're dry of painkillers. As for "graduated chemists" injecting themselves with codeine phosphate, I just don't believe you. Perhaps graduated junkies. But if you're a chemist? You can make something potent from it.
Edit: as a matter of fact, all the scholarly articles I can find on the matter say it's expressed in the brain, but don't mention blood.
 
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emkee_reinvented said:
Sounds a bit like Limpet_Chicken [RIP] he had prescription s.
For everything, and still, as UK-er, did a CWE on OTC Codeine.

Once in a while, to put too use his chemistry talent,
and making Propionyl-Morphine/ Heroine from it.
Click to expand...
not a chemist at all....this method came from the chemists and we all copy procedure....and even if i was i wouldn't have any intention to cook anything.....no longer addict and to cook something here without to be part of org.crimes group means death or long long years in jail......just takin' my 10mg prescribed diazepam and two three pills tram when i am in big pain and that's all.no weed,no drugs....for these fuckin' shit now pay the price with various health problems after all these years
 
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