Oxycodone vs Heroin (opioid naivety)

[evo4ever]

Hello all.

I've always wondered what the differences are between these two opioids. Lets say I was totally opioid naive and I was given a dose of Oxycodone and then I was given the equivalent dose of Heroin the day after and I wasn't told what I opioids I was given would I be able to tell the difference in terms of effects? Or if I wasn't opioid naive and I wasn't told which was which would I be able to identifty them?

 

[daturetard]

Hypothetically? Thats totally based on the person and experience. Theres some people who wouldn't be able to tell due to the general dopiness of either; and naivety doesn't account for if a person knows a lot about drugs.
There will be a difference in the objective effects for certain, but whether or not that difference is noted by the subject is up to them.
For example a person might put down them cleaning their room one day to them being more motivated, when in reality it was the oxy. And likewise, if unaware of what drug they're given, on the heroin day, they may or may not be able to tell that the reason they're just content to lay in their bed is due to the heroin. another example is whether or not they know that the different drugs have different effects on shit such as histamine, ie; h will make you more itchy than Oxy.
Does this make any sense?

 

[evo4ever]

Hypothetically? Thats totally based on the person and experience. Theres some people who wouldn't be able to tell due to the general dopiness of either; and naivety doesn't account for if a person knows a lot about drugs.
There will be a difference in the objective effects for certain, but whether or not that difference is noted by the subject is up to them.
For example a person might put down them cleaning their room one day to them being more motivated, when in reality it was the oxy. And likewise, if unaware of what drug they're given, on the heroin day, they may or may not be able to tell that the reason they're just content to lay in their bed is due to the heroin.
Does this make any sense?

Yeah perfectly, thanks

 

[adamvlarke]

Heroin Christ. Go for it. Please.

 

[Them Witches]

Oxycodone is made from Thebaine (paramorphine) preferred for it's stimulating effects. Heroin is made from morphine. Heroin is like 3 morphines with a chemical (diacytle) to allow it to cross the blood brain barrier easier & faster. Which is why heroin provides a ultra rapid release but wears off faster. Oxycodone crosses the blood brain barrier 3 times faster than morphine but has less sedative effects than morphine and lasts longer than morphine or heroin in the system. Oxycodone is a 10 day detox and heroin and morphine are 3-4 day detox. A drug called MoxDuo almost made it to market that combines morphine & oxycodone in 2014.

Most people do not realize that "brand name Roxicodone HCl" vs "generic Oxycodone HCl" is different by strength. The law allows the generic to be up to 20% weaker than brand name. I always prefer the brand name.

 

[LSDiesel]

Oxy you pop a pill or sniff, rarely IV as it shines best when eaten and sniffed.

Heroin you don’t pop although I have wondered if the dose was high enough,
Generally you sniff or IV heroin.

Please don’t IV drugs if you haven’t before it’s not worth the burning memory it will leave weather you succeed or fail.

 

[to_oblivion]

Oxycodone, derived from thebaine, is speedy, stimulating and an uplifting high. Heroin, very similar to morphine but stronger, is way more sedating and brings with it a “pins and needles” rush with it that no other opioid can match. I believe that if both doses were IVd, I’d be able to know what the heroin was immediately due to the rush. Someone that isn’t as experienced probably won’t have as easy as a time differentiating.

 

[Them Witches]

Oxycodone, derived from thebaine, is speedy, stimulating and an uplifting high. Heroin, very similar to morphine but stronger, is way more sedating and brings with it a “pins and needles” rush with it that no other opioid can match. I believe that if both doses were IVd, I’d be able to know what the heroin was immediately due to the rush. Someone that isn’t as experienced probably won’t have as easy as a time differentiating.

Diacetylmorphine - Heroin
Diacetyl - an organic compound, natural by-product of fermentation and can be found in foods like butter, yogurt, and wine. Apparently this compound is what gives heroin it's perfect lipid solubility. "breaks down an object & creates an ultra explosive reaction"

Lipid solubility - dissolve in or move through the lipid (fat) portion of biological membranes, like those surrounding cells. Essentially, it describes how easily a molecule can pass through the oily barriers in the body, influencing how it's absorbed, distributed, and eliminated. This is how heroin crosses the blood brain barrier ultra fast & into all parts of the body.

Heroin tricks the body into thinking it has in infection, so histamine is released instantly. Also the high lipid soluble natural, allows it to stimulate & disconnect the CNS instantly creating the "rush" feeling or separation from one's nervous system. Haldol IV, Clonidine IV, and Hydromorphone IV feel similar. Hydromorphone IV is considered to have more of a "rush" than heroin lb per lb

By adding a steroid to an opioid, it creates a similar effect of diacetyl, making the opioid more lipid soluble & helps it to cross the blood brain barrier easier/faster.

In 2014, a drug called MoxDuo almost made it to market which combined Morphine & Oxycodone ( 14mg morphine & 8mg oxycodone). Since oxycodone crosses the blood brain barrier 3 times faster than morphine, this drug was most likely rejected for potential abuse & addicting aspects because it was basically a way to market heroin.