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Misc Other Alternatives to Benzos for Acute Symptomatic Relief of General Anxiety Disorder

Rybee

Bluelighter
Joined
May 29, 2013
Messages
1,305
Hi All,

Diagnosed with GAD ~3 years ago. Given up with SSRIs/SNRIs/Tricyclics/Pregabalin/Gabapentin etc... and want to try alternatives to Benzodiazepines as I think they've largely lost their efficacy now. I'm px'd Diazepam which I do use when needed, and will be seeing my Psych for review in 2 weeks time but want to research some alternatives before I see him. He's quite open to new suggestions and medications used 'off label'. I would like to avoid daily medication, and would prefer to use medications pro re nata - such as how Benzodiazepines should really be used.

I don't know much about Barbituates, as they seem to have largely been replaced with Benzo's which are seen as a little bit safer. I've actually had a fair level of success with Beta-blockers (Propranolol & Atenolol), but they only control the physiological symptoms of anxiety such as trembling, sweating, reduced pulse etc... but they do little to actually help relax me.

As said, he's always open to new suggestions so I'd like to be as prepared as possible before we next meet to discuss alternatives, that either he or I suggest. My sleep is fine at the moment so that's good. I doubt it'd make much difference but for the sake of possible drug interactions, I currently take 3x10mg Oxycodone throughout the day for 2x herniated spinal discs - of which he's aware of.

Any suggestions would really help - I also think I'm going to give CBT another go.
 
Clonidine works for many. I actually like the stuff but decided against taking a blood pressure medication every day for fear of rebound hypertension.

You might explore lamotrigine, many report a relief of anxiety from it and it doesn't come with as high of a price as the other AEDs like depakote and lithium. Oxcarbazepine is another aed that is low in side effects.

Barbiturates are a bad idea, they really shouldn't be used at all anymore except maybe phenobarbital for tapering purposes. They are just as, if not more addictive than benzos and they carry a strong risk of respiratory failure.

There aren't many effective agents for anxiety that don't work on GABA directly or indirectly unfortunately.
 
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