In Australia, a new entry class of “selective androgen receptor modulators” is to be created in S4 (prescription medicine) of the Australian SUSMP.
Ostarine is also to be specifically scheduled in S4 under the name of
enobosarm.
www.medsafe.govt.nz/consultations/MCC-Submission-PIEDs.doc
A quick search on
forma stanzol came up Lentaron (Formestane)
Formestane has poor oral bioavailability, therefore intramuscular administration is advised... IMO its an out of date aromatase inhibitor, there are better alternatives.. If you needed one..
Formestane. A review of its pharmacological properties and clinical efficacy in the treatment of postmenopausal breast cancer.
Wiseman LR, Goa KL.
Source
Adis International Limited, Auckland, New Zealand.
Abstract
Formestane (4-hydroxyandrostenedione) is an aromatase inhibitor which significantly reduces plasma levels of estrogen and has shown antitumour activity in postmenopausal women with breast cancer. Objective response rates in heavily pretreated patients with advanced breast cancer generally range between 20 and 30% during treatment with intramuscular formestone 250 or 500mg once every 2 weeks, and a further 20 to 30% of patients experience disease stabilisation. The median duration of response is between 8 and 14 months. Highest response rates are observed in soft tissue metastases, in patients with estrogen-responsive tumours and in those showing a response to previous endocrine therapy. Furthermore, there is some evidence to suggest that higher response rates are achieved with formestane 500 versus 250mg once every 2 weeks. In comparative studies, the clinical efficacy of intramuscular formestane 250mg did not differ significantly from that of oral megestrol when administered as second-line endocrine therapy to patients with advanced disease in whom previous tamoxifen therapy had failed. In addition, formestane produced a response rate, duration of response and overall survival rate that was not significantly different from that of oral tamoxifen when administered as first-line endocrine therapy to patients with advanced disease, but tamoxifen was superior in some measures. Further investigation of these 2 agents, including the higher dosage of formestane (500mg), is necessary to confirm their relative efficacies. Formestane is well tolerated by the majority of patients; adverse events rarely necessitate cessation of therapy. The most common adverse events are local reactions at the injection site and systemic events usually related to the effect of the drug on the hormonal milieu. The systemic tolerability of formestane is similar to that of tamoxifen but better than that of megestrol. Thus, formestane is effective and well tolerated as first-line endocrine therapy for advanced disease. However, at present, it is unlikely to challenge tamoxifen in this indication, based on recent findings from a large comparative study and the fact that
formestane requires intramuscular administration. Nonetheless, formestane, which appears to have a better tolerability profile than other currently available second-line agents (including megestrol and the aromatase inhibitor aminoglutethimide), is a valuable drug for the second-line treatment of postmenopausal women with advanced breast cancer.
http://www.ncbi.nlm.nih.gov/pubmed/8894526
Test Infusion, the Formula:....... Apart from zinc I don't think anything else has been shown to be effective.... Eat more seafood...!!! (although I think the jury might be still out on DAA)....
B6 (Pyridoxine) - speeds up chemical reactions that occur in the cells of the body. This makes processes run more efficiently so that energy is produced while using the least amount of resources possible. B6 also assists in the production of B3, so it is a necessary vitamin for managing cholesterol levels. It helps bone marrow manufacture healthy red blood cells. B6 also boosts the immune system and makes it function more efficiently. Other health benefits of B6 include improved metabolism, hormone control, skin conditions, cardiac function, and kidney function.
B5 (Pantothenic Acid) - helps the body convert carbohydrates into fuel (glucose) which in turn is used to produce energy. This vitamin also plays an important role in the production of red blood cells, as well as sex and stress-related hormones produced in the adrenal glands. B5 is important in maintaining a healthy digestive track.
Calcium - strengthens bones and ensures the shape of the body part. Calcium also helps in maintaining optimum body weight in males and females. Sufficient amounts of calcium can help cardiac muscle to contract and relax properly. High calcium intake may help to significantly reduce the risk of developing kidney stones. It may also be helpful in maintaining healthy teeth and gums.
Zinc (as Gluconate Dihydrate) - has been shown to increase testosterone production, as well as increase male fertility, sperm motility, and overall sex drive. Zinc also plays a role in maintaining and improving prostate health. It may help prevent some forms of acne that are actually caused by a Zinc deficiency. It may improve immune system function, may encourage hair growth, and it may slow down or prevent balding. Zinc has also been found to improve the antioxidant capabilities of the liver. It helps produce thyroid-releasing hormones which are important to keep healthy testosterone levels. Zinc Gluconate consistently contains the lowest cadmium levels; this is important because cadmium exposure in high levels over a long period of time can lead to kidney failure. Always make sure products you take with Zinc are in Gluconate form.
D-Aspartic Acid Calcium Chelate - serves as a neurotransmitter in areas of the nervous system that specialize in hormone production. Studies have shown DAA to stimulate the release of LH and GH. They have also shown it to have a direct effect on the testes in testosterone production. A recent study showed that males supplementing with 3.12g of DAA for 12 days experienced, on average, a 40% increase in free testosterone. DAA Calcium Chelate is the most soluble form of DAA available. Other forms of DAA are not very soluble, making it very hard for your body to break down and gain the benefits from DAA.
Tribulus Alatus Extract – for a long time, it has been well known in the body building community for its natural androgen stimulation. Tribulus Alatus has had more recent studies showing its promise in increasing libido and increased serum testosterone levels. Tribulus Alatus is more effective than other forms of Tribulus because it contains six unique steroidal saponins that greatly increase testosterone production.
Tongkat Ali Root (Eurycoma Longifolia) - is recognized as an ergogenic aid that enhances the body’s adaptive response to exercise. Studies have shown that supplementation of Tongkat Ali with a weight training program caused an increase in lean body mass and a loss of fat tissue. Tongkat Ali is thought to achieve this effect by causing an increase in the body’s levels of testosterone. With increased testosterone levels, Tongkat Ali may also be beneficial as a libido-enhancer or general sexual aid.
Bulbine Natalensis - is yet another herb added to our formula that has amazing testosterone boosting effects. Bulbine Natalensis is one of the latest testosterone boosters, and while you may not have heard of it yet, you are sure to in the future, as the results it provides have proven to be very effective. Bulbine Natalensis has been shown to be effective as an estrogen reducer. Its ability to increase testosterone and reduce prolactin and estrogen makes it ideal for PCT.
Basella Alba - in recent studies has been shown to enhance testosterone production in the testes and produce testosterone in the presence of LH. This close relative of spinach has promising research on finally giving body builders the Popeye characteristics they have been dreaming about.
N-Acetyl-L-Cysteine (NAC) – is popular now for its role as an antidote to liver failure from acetaminophen overdose. It is a very powerful antioxidant that promotes rapid liver detoxification and has been shown to improve immune system function. These benefits make it an ideal ingredient in PCT.
Milk Thistle - has long been recognized as a powerful antioxidant that helps to detoxify and repair the liver. There are hundreds of studies confirming the ability of Milk Thistle to protect the liver. This is a must-have ingredient in PCT.
Hawthorne Berry - is another antioxidant that is especially useful to protect against heart disease and help control high blood pressure. In recent studies, Hawthorne Berry has been shown to increase coronary artery blood flow, improve circulation, and lower blood pressure.
Celery Seed Extract - studies have suggested that Celery Seed Extract may help lower blood pressure and cholesterol as well as protect the liver from damaging substances. It is an all-around good ingredient for PCT.
Grape Seed Extract - is a powerful antioxidant used to treat a wide range of health problems and free radical damage including heart disease. Additionally, the antioxidants in Grape Seed Extract have a protective effect on blood vessels which may help prevent high blood pressure.
Pygeum Africanum Bark - effectively helps in relieving symptoms associated with BPH or prostate swelling. Theoretically, Pygeum Africanum Bark may also help in improving sexual health in men.
