• N&PD Moderators: Skorpio | thegreenhand

Ketamine salts solubility

I read somewhere, that Xanax costs 4 cents a piece to make them. Not sure the strenght.
I hate CVS. They tried to make me go there, and they don't carry my particular pain killer. So I had to find another pharmacy.
 
trying to avoid making another mega post so I’ll be quite briefe with this example.
P53 is most famous for causing apoptosis but this is only a Single function among a massive range of effects most of which are actually cytoprotective. P53 induced apoptosis is due to transcriptional upregulation of proapoptotic downstream proteins like PUMA, BAX and BAD. if these proteins are inhibited or knocked out, P53 accumulation will often make cells unusually resilient to environmental stresses via mechanisms like increased energy production, DNA repair, stopping the cell cycle/cell division, decreasing harmful levels of glycolysis and activating antioxidant enzymes on a large scale.
According to one study, I read the P 53 inhibitor, pifathrin Alpha and analogues offer unique benefits for neuro protection as well as protection against radiation and chemical toxicity because these inhibitors only target the proapoptotic Domain of P53 whilst leaving all of the beneficial functions intact.
 
1-(2,6-dimethyl-pyridine-4-yl)-2-aminopropane.png


DAFT_PUNK
1-(2,6-dimethyl-pyridine-4-yl)-2-aminopropane

The Molecule With Horns.
 
1-(3,4-dimethylphenyl)-2-methylaminopropane.png


ROUGH_RIDER
1-(3,4-dimethylphenyl)-2-methylaminopropane

Another horny molecule. Kin to the discontinued Xylopropamine.
 
I'm currently on slow realise Morphine - 40mg in the morning, 40mg at night. I take it for chronic pain - Crohn's, Ehlers-Danlos, slipped desk, osteoporosis etc.

Would I get better pain relief if I switched to Dihydrocodine with an agonist like promethazine?
My pain is due to muscular tension, but I find that promethazine is useless combined with any opiate. Not much experience with DHC but morphine is stronger.
 
I'll try to get the videos from my girlfriend, but there is a well known pain specialist who suggest things like duloxetine, gabapentin, I the NMDA antagonists like memantine (not saying that he suggest that drug, just that class similar to that drug) as medications that can help pain treatment.

Just want to throw out a little anecdote, my mother (and me and my brother of course, yay!) have Ehlers-Danlos. My mother does take duloxetine and gabapentin for her pain. The duloxetine might have worked a tiny bit early on, and the gabapentin seems to have a much more definitive effect on her pain, but there is tolerance with it. You're going to keep trying to escalate on the dose, but it's not actually going to make it much better after a certain point (research on gabapentin is out there that shows the ceiling dose on its therapeutic effects is way lower than the maximum daily dose). As long as you need constant pain management, rather than periodic help with pain, this is not going to cut it. I think this is especially true in this case since it seems they've got a lot more going on than just Ehlers-Danlos.

Maybe they could benefit from using these on top of the opiates, but not instead of them.
 
Hello guys please reply,
I want to extract dex fromy Vyvanse using trypsin enzyme method, I can't open blue light .ru , I tried vpn and onion browser didn't work , if u be kind tell me how it's done ,thanks
 
(2S,5R,6R)-2-carbomethoxy-6-(2-(3,4-dichlorophenyl)-1-methylethyl-amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane.png


SNIFFLESS
(2S,5R,6R)-2-carbomethoxy-6-(2-(3,4-dichlorophenyl)-1-methylethyl-amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane

An Antibiotic With Bite.
 
I'm just curious: how intentional are your designs? Sometimes I think to myself, Oh that might be interesting, and other times I think you're playing Lego with theoretical chemical moiety arrangements. Besides the obvious entertainment value, what are you aiming to do with this giant thread?
 
I read somewhere, that Xanax costs 4 cents a piece to make them. Not sure the strenght.
I hate CVS. They tried to make me go there, and they don't carry my particular pain killer. So I had to find another pharmacy.
0.04 cents to be exact per pill. This is for 1 , 2mg Clonazepam Teva. Than the pharmacy charges $46.84 for 60 tablets. They only pay 2.4 dollars for 60. This makes me sick.
 
Many Of These Drugs Have Been Made And Tested On Me. I Like Taking New Drugs, Especially Ones I Have Posted.

1-(3,4,5-trichlorophenyl)-2-methylaminopropane.png


SUPERFREAK OR IS IT JUST ANOTHER JIM?
1-(3,4,5-trichlorophenyl)-2-methylaminopropane
 
1-allyl-3-methoxy-4-hydroxybenzene.png


EUGENOL
1-allyl-3-methoxy-4-hydroxybenzene

excess HBr(g)

1-(3,4-dihydroxyphenyl)-2-bromopropane.png


1-(3,4-dihydroxyphenyl)-2-bromopropane

CH2Cl2, KOH

1-(3,4-methylenedioxyphenyl)-2-bromopropane.png


1-(3,4-methylenedioxyphenyl)-2-bromopropane

CH3NH2(g), THF

1-(3,4-methylenedioxyphenyl)-2-methylaminopropane.png


ECSTASY
1-(3,4-methylenedioxyphenyl)-2-methylaminopropane

3 Steps.
 
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1-(2,6-dimethoxypyridine-4-yl)-2-aminopropane.png


CARLITO
1-(2,6-dimethoxypyridine-4-yl)-2-aminopropane

from

4-aza-3,5-dimethoxybenzaldehyde.png


4-aza-3,5-dimethoxybenzaldehyde
 
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1-(pyridine-4-yl)-2-ethylaminopropane.png


DJ SAMMY "THAT GIRL'" AGUILERA
1-(pyridine-4-yl)-2-ethylaminopropane

1-(pyridine-4-yl)-2-methylaminopropane.png


MARK
1-(pyridine-4-yl)-2-methylaminopropane

1-(pyridine-4-yl)-2-aminopropane.png


JUNIOR
1-(pyridine-4-yl)-2-aminopropane

from the oxidation of

4-methylpyridine.png


4-methylpyridine, a natural product
 
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(2S)-1-methyl-2-(pyridine-4-yl)-pyrrolidine.png


LAFFY_TAFFY_TOBAKKY (isonicotine)
(2S)-1-methyl-2-(pyridine-4-yl)-pyrrolidine
 
The following 3 compounds were inspired by Nucenta.

N,N-dimethyl-1-amino-3-phenyl-2-(2S)-methylpropane.png


ANALGEAZYSIACKER
N,N-dimethyl-1-amino-3-phenyl-2-(2S)-methylpropane

possible pain killer

Hypothetical Synthetic Outline:

KCN + 1-phenyl-2-bromo-propane, then
reduce triple bond to the primary amine with NaBH4 in alcohol and N,N-dimethylate that product with 2 molar equivalents of formaldehyde and NaBH3CN in MeOH @ pH of 7.

N,N-diethyl-1-amino-3-phenyl-2-(2R)-methyl-3-oxopropane.png


SLACKER_CRACKER
N,N-diethyl-1-amino-3-phenyl-2-(2R)-methyl-3-oxopropane

From 1-phenyl-1-oxo-2-bromo-propane. That oxo would prolly need protecting then deprotecting with something like ethylene glycol. Substitution of 2 equivalents of formaldehyde with acetaldehyde yields this latter N,N-diethyl compound.

SLACKER_CRACKER is then the precursor for

N,N-diethyl-1-amino-3-carbomethoxy-3-phenyl-2-(2S)-methyl-propane.png


FANCY_NANCY
N,N-diethyl-1-amino-3-carbomethoxy-3-phenyl-2-(2S)-methyl-propane

using the Anderson benzylic-OH to carbomethoxy functional group named rxn.
 
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How long do I have before the nasal spray bottle gets to contaminated/risky to continue using and would wiping it off with alcohol wipes or something similar to cleanse any bacteria on it, be beneficial at all?


What would be better than water to use for cocaine and would I want to use a different "solvent" than what is considered preferred to use for Cocaine compared to Ketamine I'd guess would require a different "solvent" but I honestly got no idea lol?
I would use saline for those.
 
1-(2-phenyl-1-methylethyl)-2-(4-azabenzoyl)-hydrazine.png


GREAT_EXPECTATIONS
1-(2-phenyl-1-methylethyl)-2-(4-azabenzoyl)-hydrazine

Keywords: Amphetamine, isoniazid (INH), iproniazid, phenelzine.

This bad boy has everything going for it. It might help treat adhd, depression, and tuberculosis. Or it might make one drop dead. I doubt that, though.

INH + 1-phenyl-2-halo-propane --> Wallah (viola)! Something Like That. The halogen used could be chloro, bromo, or iodo.

You Have To Want To Believe To Believe.

Yours Truly,
Pip
 
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