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RCs New Cath: No name, No cas - 2-amino-1-(1,3-benzodioxyl-5-yl)-3-methylbutan-1-ol

j1m1th1ng

Greenlighter
Joined
Jul 7, 2011
Messages
28
dCInBNS.jpg


Its being called m2 8)

Vendor is legit. Done alot of biz with him. I was just curious if anyone could ID this or know what it was or what it effcts are apt to be.
 
The image is cut off at the end so no one can answer your ?

The vendor doesn't even know the name of what he is selling, are you kidding me? This seems so beyond suspicious. If it doesn't even have a CAS number, then that means that it has never been mentioned in any scientific literature. I find that so goddamn sketchy. Stay away to stay safe.
 
Yeah, fuck those lame marketing names. It's no different than "spice" or "bath salts" IMO. At least wait until a few other unfortunate guinea pigs have tried it out.
 
The image is not cut off. The IUPAC name would be: 2-amino-1-(1,3-benzodioxyl-5-yl)-3-methylbutan-1-ol. Rolls off the tongue, dunnit?

It is not a cathinone or a beta ketone. It is a beta-hydroxy phenethylamine, like ephedrine. No successful beta-hydroxy RC's that I know of. Well, except for the BOx series by Shulgin, but those are psychedelics. This looks like it's trying to be an entactogen or stimulant. I say "trying" because, while most stims are fairly tolerant of lengthening the alpha chain, I can't think of any that have an isopropyl group or anything bulky like that.

Doesn't look too promising based on structure alone. Not all that has a methylenedioxy group is gold. But who knows? Could be the bomb. Predicting activity from structure is an art at best, blind guessing at worst.

There's a lot of hating on RC's on this and other forums, especially new, untested ones, and ESPECIALLY ones being marketed as "next-best-whatever". Don't forget: all synthetic drugs start off as RC's. Some, like ketamine and methamphetamine, go through extensive testing before mass production. Others (LSD, MDMA, 2C-X, mephedrone, mdpv) do not. Testing and FDA approval do not necessarily translate to absolute safety. Lots of compounds get the stamp of approval that are toxic or worse. Taking ANY drugs is risky. Granted the risk is easier to assess for well-worn compounds, harder when you are one of the first guinea pigs.
 
That drawing is a little misleading at first glance, here's a better one. Same structure, just re-arranged so it resembles traditional amphetamines/ketones/etc, otherwise it looks like beta-hydroxy-N-dimethyl-MDA:

bDR5Yvc.png


Also, it's not a cathinone/beta-ketone. If it was, it'd look like this instead:

EEzja3G.png


No successful beta-hydroxy RC's that I know of. Well, except for the BOx series by Shulgin, but those are psychedelics.

Just to avoid any confusion, it's only BOHD that Shulgin created that was a beta-hydroxy phen, the rest of the BOx series are beta-methoxy based phens. :)
 
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And BOHD was not reported to have psychedelic effects, at least from the one trial.

"QUALITATIVE COMMENTS: (with 50 mg) At about the two hour point, there was a precipitous drop of blood pressure (from 120/72 to 84/68) although the pulse stayed steady at 60. This trend had been apparent in earlier trials, and was being watched carefully. No further tests are planned. "
 
EEzja3G.png


I would expect this to be a straightforward NDRI.

bDR5Yvc.png


I would expect this to be a beta adrenergic agonist.
...
Both look like pieces of shit! :P

ebola
 
You never know though…From it’s structure it’s feasible that it could act as a serotonin and dopamine releasing agent, as well as having adrenergic agonist properties.

EEzja3G.png


I would expect this to be a straightforward NDRI.

bDR5Yvc.png


I would expect this to be a beta adrenergic agonist.
...
Both look like pieces of shit! :P

ebola
 
I would expect the B-keto compound to be eseentially an analogue of butylone. The B-hydroxy compound would be less potent still, but probably still active as a NDRI.

The "methylenedioxy-ephedrines" are typically more cardiac trouble than they are worth. They are first-line metabolites of some of the cathinones that have a higher propensity for side effects.
 
dCInBNS.jpg


Its being called m2 8)

Vendor is legit. Done alot of biz with him. I was just curious if anyone could ID this or know what it was or what it effcts are apt to be.

So, the beta-hydoxy is, as often stated, a totally useless substituent that only serves to make the compound act like ephedrine, which is to say, hypertensive and without any real chance of being fun. The OH acts as a hydrogen bond donor which radically modifies the pharmacology of the compound, so it acts on NET and adrenergic receptors with very little dopamine/serotonin action. The difference between cathine and amphetamine is almost entirely due to pharmacology and unrelated to BBB penetration as is sometimes believed:

http://www.ncbi.nlm.nih.gov/pubmed/1570407

It is however possible that the vendor depicted the molecule wrong. If you type the SMILES string CC(C)C(N)C(O)c1cc2OCOc2cc1 into a depictor, you get the depicted molecule. The ketone differs by only one character: CC(C)C(N)C(=O)c1cc2OCOc2cc1, and because hydrogens are not often included in SMILES strings one could certainly mistype the former when meaning the latter. Especially if the compound is classified as a cathinone; it would be new even for a vendor to be so dumb as to sell ephedrine.

What I don't get is why they went with the beta-oxo derivative at all, the simple methylenedioxy-"alpha-isopropyl"-phenethylamine MDiP is not, to my knowledge, a known compound.
 
well he has always been a fairly good guy and seems to actually behind the production of this stuff not juste a sales rep. I will run some of what you guys said past himself and see what his response is. Also sorry about the cut off image was not intentional. This does seem to be something new and I might pick up a small bit just to see if it has any worth while to it I will notice be calling it m2 can any of you suggest a proper name for it?
 
Ordered some reagent tests. Appearance is noting special. Allergy test proved fine. Proceeded to 25mg...a touch of something here for sure. Will report back with reagent.
 
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