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Misc MXE (methoxetamine) + Seroquel (Quetiapine), atypical anti-psychotics

D

daveykronick

Bluelighter
Joined
Aug 3, 2009
Messages
119
Location
Pacific North Western, United States
Will Seroquel (quetiapine) diminish the effects of MXE? Could you use it to kill the intense moments of unpleasant dissociative trippyness and retain the sedating/anesthetic qualities? How about Zyprexa (olanzapine)? I bet it would kill most of the effects as it is a very strong atypical anti-psychotic and would likely just put one to bed (as long as you are intolerant to anti-psychotics). I ask this question because I will be using small amounts of methoxetamine in the 5-10mg range (estimated, just using a match head or two's worth) to potentiate buprenorphine and to help me lower my bupe dosage, as I have been struggling to do so for quite some time. I am currently on 4mg of bupe a day and would like to get down less than 1mg, but I am shooting for 1mg to be realistic. I have jumped from 4mg bupe to 1mg in the past without much trouble, but it is now substantially harder as my psychological addiction has grown. Is methoxetamine when taken orally more opiate-like in the sense it is less of a mind fuck due to how it is metabolized? That's what I have read but it is all anecdotal.

In any case, tomorrow morning I am taking the smallest amount methoxetamine possible, orally, with the hope of potentiating 1mg of sub-lingual buprenorphine. If things get out of hand I will use the Seroquel (quetiapine) to try and kill the effects, but I doubt there will be many un-pleasantries if I keep the dosage of the methoxetamine on the low end (5 -10mg max). If I don't experience opiate potentiation at a low dose of methoxetamine then I will increase it slowly to the 20-30mg range, orally, on different occasions for each dosage change. If I do so I can expect some of the weirder effects to come out so I will have the Seroquel (quetiapine) and Zyprexa (olanzapine) on hand to attempt to kill the unpleasant thoughts.

So, ladies and gentleman, this is a two-fold experiment. Will MXE potentiate bupe? Can an anti-psychotic kill a bad MXE trip? We will find out in the coming days/weeks as I report back with my findings.

So, what do you guys think?
 
Today is the second day of my experiment (less than 24hrs has passed) and I only got 4hrs of sleep due to insomnia last night. Yesterday I dosed 5-10mg (a match-head's worth) 3x, each time 45 minutes before a bupe dose and I did find that I could feel the bupe more and got itchy and got the glow and everything but it was very subtle. Also, the methoxetamine did at times overpower the bupe. Today I woke up up around 4:45am and took 20-30mg mxe and 1.0mg - 1.5mg dissolved in water (after brushing teeth and rinsing with alcoholic mouthwash). At first it was great because I was experiencing the strange effects of the mxe while being grounded by the bupe. Well, I eventually developed this toxic feeling in my heart and veins (bp) which I didn't check but I guarantee is minor because when I first got this stuff the same thing happened only 10x worse and I went to the ER and they did ECG and everything and nothing was abnormal so I am guessing it is safe and it is just a side-effect of the mxe.

Have you guys gotten a toxic/poisoned feeling from mxe before? I felt like my heart and bp were messed up but like I said they weren't and I was fine. Do you think this material is safe? It's from a highly reputable Spanish vendor and was said to be 98%. I wonder if maybe there was some kind of toxic byproduct or contamination. My friend (who went in on it with me) loved it at first, then claimed to have gotten a "toxic" feeling and reported having some kind of rash (which he sent a photo of). I don't think the rash is related as I have searched all over the internet and didn't find one case of anyone getting a rash from a bad batch of mxe.

I don't know what to do. I finally find something that helps tolerance and makes me feel the bupe more but it feels kinda toxic (at least at an estimated 20-30mg, eyeballed). I know I really should be weighing out doses but I've just been taking match-head amounts and this last time took 3 of those match-head amounts which I believe came out to a total of 20-30mg because it is quite dense. I definitely got some effects off it that where actually pretty euphoric and comfortable. On a positive note, the toxic feeling is fading, my heart feels basically back to normal now after taking 0.2mg clonidine. Still feel a little off with a headache but better than before.

Should I continue to use mxe to potentiate my bupe doses? Can I do this daily or every other day (for say a month) without too much damage? What kind of side-effects have you guys gotten from mxe and what are the dangers that you guys know of. I know its a fairly new chemical so knowledge is scarce but help me out. You guys think I got a bad-batch or is it just a normal side-effect from the mxe. I have to say that I wasn't feeling anxious or anything when the toxic heart/bp feeling came on but I became a bit on edge afterward, but now it has died down a little bit to a tolerable level.
 
daveykronick said:
Will Seroquel (q
So, ladies and gentleman, this is a two-fold experiment. Will MXE potentiate bupe? Can an anti-psychotic kill a bad MXE trip? We will find out in the coming days/weeks as I report back with my findings.

So, what do you guys think?
Click to expand...

Don't expect to get that high on anything when on antipsychotics
Weed is the ONLY drug that works on me anymore since i'm on Latuda.
I can't trip, speed, dope, or anything. Ive tried it all
 
It all depend on the dose of antipsychotic, I take Seroquel and Abilify and I still can trip on plenty of drugs including stimulants. I tried MXE too and it works.
 
QUARE said:
It all depend on the dose of antipsychotic, I take Seroquel and Abilify and I still can trip on plenty of drugs including stimulants. I tried MXE too and it works.
Click to expand...

You're right about that. The Seroquel (quetiapine) is an anti-hystamine at lower doses (25-100mg) and then works on other neurotransmitters from 150-400mg and finally at about the 500mg + mark it is a dopamine receptor agonist. I know Zyprexa (olanzapine) is a pretty dopamine receptor agonist so I keep some on hand. I am just concerned with the toxic feeling of the MXE, the feeling that my heart is under stress, it's hard to explain. Does anyone have a similar experience with MXE causing this side-effect? It only seemed to occur at the 20-30mg + up mark. It is very concerning so I am skipping my dosage tomorrow and giving it a few days and trying again. As for the potentiation, I feel like it does work, but it's a subtle boost. Still, it's something.
 
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