Here's some info:
Morphine hydrochloride:
Derivative Type: Trihydrate
Properties: White flakes or crystalline powder; bitter taste. Loses its water of crystn at about 100° and usually becomes yellowish. mp about 200° (dec). [a]D25 -113.5° (c = 2.2 in H2O, anhydr basis). One gram dissolves in 17.5 ml water, 0.5 ml boiling water, 52 ml alc, 6 ml alc at 60°; slowly sol in glycerol. Insol in chloroform, ether. pH about 5. Protect from light. LD50 in mice (mg/kg): 226-318 i.v. (Buchwald, Eadie).
Morphine sulfate:
Derivative Type: Pentahydrate
Properties: White, fine odorless crystals or powder, or cubical masses. Loses some H2O at ordinary temp; about 3H2O (7.1%) at 100°, the remainder at 130°. Discolors on exposure to light. mp ~250° with decompn when anhydr. [a]D25 -108.7° (c = 4 in H2O, anhydr basis). One gram dissolves in 15.5 ml water at 25°, 0.7 ml water at 80°, 565 ml alcohol, 240 ml alcohol at 60°. Insol in chloroform, ether. pH about 4.8. Keep well closed and protected from light. Even ampuled aq solns of morphine sulfate will turn brown on storage. No loss of analgesic potency and no increase in toxicity has ever been demonstrated for such discolored solns: J. Am. Med. Assoc. 155, 28 (1954); J. Pharm. Pharmacol. 2, 673 (1950).
There's no info on the anhydrous salts.
