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Opioids Morphine / Oxycodone, what is better for pain?

benzoman12345

Ex-Bluelighter
Joined
May 22, 2013
Messages
837
Location
UK
Morphine / Oxycodone, what is better for pain and why ?

I'm not familiar with Oxy really only ever had a 20mg norm one time

I can get OC40s ER but they are expensive

I know what Morphine 40mg would feel like, what would oxy 40mg be like

It can be made IR if neccessary
 
This is really a subjective topic. I personally prefer Morphine sulfate over Oxycodone hydrochloride. 40mg of OxyContin is equivalent to 60mg of MSContin. Since these are continuous release tablets, this amount would be delivered slowly over a 12 hour period. 40mg of OC will probably have your peak plasma levels sitting around what 15mg of immediate release would have you at.
 
An oxy 40 blows 40 mg of morphine away males it look like nothing. I needed 100 mg od morphone just to be well back in the day when a oxy 40 would do the trick.
 
Good news, cos I want to try an split them in half and see if I can get away with that because of the price, double digits for 1 pill

I get scripted DHC/Para 30/500 8 tabs per day but I don't like paracetemol man ,

I'd happily swap my script for something half the dosage with no paracetemol
 
It's hard to say, man, both oxy and morphine are subject to high inter-individual variability. Oxycodone is more potent per mg, but even that varies. Typically, it is 1.5x the strength, so that 40mg oxycodone is roughly equivalent to 60mg CHRONIC oral morphine, but, for some people it is double the strength. And for a small portion, oxy is only slightly more effective, and since morphine's BA is dose dependent, they can even be equi-potent at high doses. But in general, 40mg oxy will be more effective. You would likely need 60mg morphine to give the same effect. However I personally prefer morphine over oxy. I mean 60mg morphine would be roughly equal to 40mg oxy, however I find morphine to be MUCH better for analgesia, at equal doses of course. What I mean is, 40mg oxy would be about the same strength as 60mg oral morphine, however I find the 60mg morphine dose more effective as an analgesic. I mean morphine has a much higher binding affinity than oxycodone, and is just a stronger more reliable opioid. Morphine also provides longer lasting analgesia at high doses(despite oxy having a slightly longer half-life). But remember, chronic oral morphine is roughly twice as potent as acute oral morphine. This is because the BA of morphine increases with repeat dosing(also, M6G, morphine's potent and long lasting metabolite seems to play a role in this as well.) So if the morphine dose doesn't initially cut it, you can increase it slightly, but just be patient, as it will take a few days to reach full strength.

Anyway, it is an individual thing, really, but I would suggest starting with morphine. You should also be able to get oxy ir for breakthrough, so really you will have both. Which is a good thing, because other than methadone(or diamorphine, which you obviously can't get) morphine, with oxy as breath through is the most effective opioid regimen for chronic pain.(And this isn't just opinion, studies back this up, demonstrating that a combination of oxycodone and morphine is more effective, AND has less side effects than an equal dose of either drug alone)

So try to get morphine, with oxy for breakthrough. But whatever you do, DO NOT get the op's(the new OxyContin). They fucking suck, you cannot break the time release, which means even in a case of severe pain, you'll have to wait 3-4h for then to take effect, and literally everyone I know who has been prescribed them hated them so much they eventually switched meds(including people who don't even abuse they're medication) not to mention, they're is a chance you will shit gel, with no effects. MScontin does not have the same problem, and you can defeat time release by simply grinding them down into a powder.

Anyway, sorry for the long post, and good luck!!!
 
My goal is to wait it out until they try me on good old morphine

Oxy will never happen in a million years

In this county you've gotta buy half of your medicinal needs privately :)
 
But one more thing, if you are prescribed Dihydrocodiene, well I can't imagine any doctor that would immediately switch you from DHC to 40mg oxy, that is like going from Vicodin to fucking methadone(though I have seen that happen!) so just a warning, but it appears you have already set this up, so good for you.

For everyone else: I don't mention breaking the time release to abuse medication, but as a pain patient, pain varies from day to day, and sometimes you need an IR dose, especially since many doctors refuse to write rescue medication...
 
I may get tried on ER DHC in a few months time,
if I tell them that's no good
then in ANOTHER few months time they might try me on like 10mg MST ,
then ANOTHER 3-5 months , theyl up that

It took a relative about 3 years to finally get Oramorph , fuck that is my dream , that is the definition of a painkiller !!
 
Oh I get it, you are getting them on the black market. Yeah, I'd take morphine over Oxys anyway for pain, however, most people find oxy more recreational. But don't fuck with OP's(OxyContin) they suck, and are ridiculously overpriced. Morphine is harder to find, but is actually pretty cheap. But your doc shouldn't have much if a problem trying morphine, but you will likely get started on a ridiculously low dose(15mg mscontin twice per day, or 10mg ir 3-4x, or possibly even 5mg, 4, or if your damn Lucky, 5x a day.
 
Well I can't tell you on how to deal with doctors, but you need to find a good pain management doc, it shouldn't take that long. A friend was prescribed hydrocodone for a couple of years, at gradually increasing doses. Then his condition deterioratied rapidly, almost overnight his pain got exponentially worse, so within a few months he went from 90 Vicodin hp per month, to 120 percent 10's per month, to 60 roxi 30's, and eventually got 135 roxi 30's and 60 mscontin 15's on top of that. So he went from getting 30-40mg hydro per day, to over 100mg oxy and 30ng morphine, in a period of less than 6 months! So you just have to find the right doctor...
 
I'm in the pain clinic in my local hospital but I am UK so it is NHS

3-4-5 months between appointments just to get 1 tiny adjustment made you don't even get a proper converstation

They are all like that unless you have money for private then pain issues can be a bastard.
 
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