Trogdor
Bluelighter
Preface:
I posted this here because I figured I'd get a lot of answers in PD, but few of them would be relevant.
Now, mescaline extraction is not something I've done before, nor intend to do, as it's illegal. However, there's currently a lot of talk about it in PD which peaked my interest, and even though actually performing the extraction is illegal, thinking for myself is a chemical process which nobody can stop me from doing.
The main problem I have with every mescaline extraction tek I've read is that it requires the mescaline to be converted from freebase to salt to freebase to salt again. I don't know a lot about organic chemistry (in fact almost everything I know I learned thanks to bluelight), but that seems very inefficient to me, if nothing else, in terms of time and effort.
Which is why after perusing several teks and considering different elements of each, I've come up with a rudimentary procedure that I think would work to extract the alkaloids relatively purely without the need for rebasification and resalinization steps. Most of it is based off of assumptions which I will list at the end of this post. Please feel free to correct any assumptions and/or problems/inefficiencies with this procedure, as well as provide any relevant information I may not know. Thanks in advance.
Oh yeah, if this really does work, just think what I could do if I actually knew what I was talking about... 8)
Procedure:
1. Using the San Pedro Alkaloid Extraction For Dummies (an appropriate title), follow steps 1 and 2 using a volatile acid, such as HCl (or H2SO4, I'm told that it reacts exothermically with water though). This should produce a solution of HCl + water, cactus alkaloids in hcl salt form, and impurities (of a non-specified nature).
2. Using adequate ventilation, evaporate this liquid in the container you wish to use next.
3. Reconstitute with warm ethanol until your material is just dissolved. Allow to cool to room temperature.
4. Add a quantity of acetone to the ethanol solution. Mix well. Allow to sit.
5. Filter precipitated mescaline hcl.
6. If necessary, repeat steps 2-5 before proceeding to step 7.
7. If necessary, do this recrystalization procedure using a polar protic solvent (e.g. ethanol) instead of a non-polar solvent (it's from a dmt extraction tek). If necessary do it twice.
You *should* now be left with relatively pure mescaline hcl (and other related alkaloids).
Assumptions:
1. The defatting step in the other tek actually works, and without significant loss of alkaloids.
2. The only polar compounds in the solution that step 1 creates are the alkaloids in salt form.
3. If there are any unwanted polar compounds in said solution, step 7 will remove them.
4. Provided enough is added, the acetone added in step 4 will mix with the ethanol and effectively convert it into a non-polar solvent, thus causing any polar compound dissolved in it (i.e. alkaloid salts) to precipitate out.
5. Acetone should not be added to HCl, thus necessitating steps 2 and 3. This is just an unfounded hunch.
6. Ethanol is an appropriate solvent for step 3 and is preferred over other polar protic solvents.
I posted this here because I figured I'd get a lot of answers in PD, but few of them would be relevant.
Now, mescaline extraction is not something I've done before, nor intend to do, as it's illegal. However, there's currently a lot of talk about it in PD which peaked my interest, and even though actually performing the extraction is illegal, thinking for myself is a chemical process which nobody can stop me from doing.----------------------------------------
The main problem I have with every mescaline extraction tek I've read is that it requires the mescaline to be converted from freebase to salt to freebase to salt again. I don't know a lot about organic chemistry (in fact almost everything I know I learned thanks to bluelight), but that seems very inefficient to me, if nothing else, in terms of time and effort.
Which is why after perusing several teks and considering different elements of each, I've come up with a rudimentary procedure that I think would work to extract the alkaloids relatively purely without the need for rebasification and resalinization steps. Most of it is based off of assumptions which I will list at the end of this post. Please feel free to correct any assumptions and/or problems/inefficiencies with this procedure, as well as provide any relevant information I may not know. Thanks in advance.
Oh yeah, if this really does work, just think what I could do if I actually knew what I was talking about... 8)
----------------------------------------
Procedure:
1. Using the San Pedro Alkaloid Extraction For Dummies (an appropriate title), follow steps 1 and 2 using a volatile acid, such as HCl (or H2SO4, I'm told that it reacts exothermically with water though). This should produce a solution of HCl + water, cactus alkaloids in hcl salt form, and impurities (of a non-specified nature).
2. Using adequate ventilation, evaporate this liquid in the container you wish to use next.
3. Reconstitute with warm ethanol until your material is just dissolved. Allow to cool to room temperature.
4. Add a quantity of acetone to the ethanol solution. Mix well. Allow to sit.
5. Filter precipitated mescaline hcl.
6. If necessary, repeat steps 2-5 before proceeding to step 7.
7. If necessary, do this recrystalization procedure using a polar protic solvent (e.g. ethanol) instead of a non-polar solvent (it's from a dmt extraction tek). If necessary do it twice.
You *should* now be left with relatively pure mescaline hcl (and other related alkaloids).
----------------------------------------
Assumptions:
1. The defatting step in the other tek actually works, and without significant loss of alkaloids.
2. The only polar compounds in the solution that step 1 creates are the alkaloids in salt form.
3. If there are any unwanted polar compounds in said solution, step 7 will remove them.
4. Provided enough is added, the acetone added in step 4 will mix with the ethanol and effectively convert it into a non-polar solvent, thus causing any polar compound dissolved in it (i.e. alkaloid salts) to precipitate out.
5. Acetone should not be added to HCl, thus necessitating steps 2 and 3. This is just an unfounded hunch.
6. Ethanol is an appropriate solvent for step 3 and is preferred over other polar protic solvents.
Last edited:
