Phenethylamines Mescaline and SSRIs

[EternalDreamer]

Just wondering if anyone here has any firsthand experience using mescaline (specifically from San Pedro cactus) while on an SSRI like Prozac? Is this safe to combine?

I'm on a low dose of Prozac, and I have safely combined with psilocybin, with full effects.

 

[MindlessBilly]

The literature says no, the fact mescaline is a phenethylamine is also a larger concern than taking psilocybin due to the stimulant effects of mescaline which can increase cardiovascular issues when combined with prozac.

Personally when I took SSRIs (lexapro) and took LSD the trip was far from enjoyable, bordering on a psychotic episode.

I can't tell you what to do, I can only share information and my own experience, all I can say is if you do decide to go down this path start with a low dose and have a trip sitter.